Sensor for edema

• US 7,860,567 B2
• Filed: 08/31/2006
• Issued: 12/28/2010
• Est. Priority Date: 08/31/2006
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Belalcazar, Andres, Stahmann, Jeffrey E.
• Primary Examiner(s): Getzow; Scott M
• Assistant Examiner(s): Dietrich; Joseph M
• Application Number:
  US11/469,018
• Publication Number:
  US 20080058885A1
• Time in Patent Office: 1,580 Days
• Field of Search: 600/508, 600/510, 600/542, 607/17, 607/18, 607/20, 607/42, 607/34, 607/35
• US Class Current: 607/17
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control
• CPC Class Codes: A61N 1/37288 Communication to several implantable medical devices within one patient
• CPC Class Codes: A61N 1/378 Electrical supply

Abstract

A sensor is located within the body of a subject, such as for capturing pacing pulses transmitted as part of cardiac therapy from an implanted cardiac function management device. Counted pulses may be used to derive the onset of pulmonary edema within the body through pulse characteristics such as frequency and amplitude. The sensor may be anchored within mediastinal pleura or the airway of the body with the ability to communicate wirelessly to one or more other medical devices, such as an implanted cardiac function management device. It may also adjust transmission of the communication to discriminate among multiple sensors. Methods of use are also described.

Claims

1. A system comprising:

a first device including a first electrode and a second electrode, at least a portion of which is adapted to reside in a body of a subject, wherein the first device is configured to measure a physiological first parameter, the first device including an energy collection unit coupled to the first and second electrodes; and

an implantable second device physically separate from and unattached to the first device, the second device configured to issue cardiac pacing pulses, wherein the energy collection unit of the first device is configured to aggregate energy collected from the cardiac pacing pulses by the first and second electrodes over two or more cardiac cycles, wherein the measurement of the physiological first parameter is a function of a quantity of the energy aggregated over the cardiac cycles.

2. The system of claim 1, in which the second device includes a cardiac function management device.

3. The system of claim 1, wherein the first device includes a communication module configured to transmit information about the first parameter via the first and second electrodes.

4. The system of claim 3, in which the communication module of the first device is configured to transmit information wirelessly, and comprises one or more of an ultrasonic transmitter, an inductive transmitter, and a body conductive transmitter.

5. The system of claim 4, in which the communication module is configured to transmit information synchronous to a pacing pulse delivered by the second device.

6. The system of claim 5, in which the communication module is configured to adjust transmission of information to permit communication from at least a third device separate from and unattached to the first device.

7. The system of claim 1, wherein the first device is sized and shaped to be fixated within the airway of a subject.

8. The system of claim 1, wherein the first device is sized and shaped to be fixated within the mediastinal pleura region of a subject.

9. The system of claim 1, wherein the first and second electrodes are configured to fixate at least a portion of the first device within the airway of a subject.

10. The system of claim 1, wherein the first and second electrodes are configured to fixate at least a portion of the first device within the mediastinal pleura region of a subject.

11. The system of claim 1, wherein the second device includes a lead, and wherein the first device is located approximately 2 cm from the lead of the second device.

12. The system of claim 1, wherein the first device is configured to capacitively store the energy collected from the cardiac pacing pulses.

13. The system of claim 1, wherein the first device is configured to measure a tissue fluid accumulation.

14. The system of claim 1, wherein the first device is configured to measure a tissue fluid accumulation as a function of the quantity of the energy aggregated over the cardiac cycles.

15. A method comprising:

collecting energy using first and second electrodes of a first device, the energy collected from cardiac pacing pulses issued from an implantable second device, the first device being at least partially implanted at a first location within a body of a subject, the first location being different from a location of the second device, wherein the second device is physically separate from and unattached to the first device;

aggregating the energy collected from the cardiac pacing pulses over two or more cardiac cycles using an energy collection unit of the first device, the energy collection unit coupled to the first and second electrodes; and

measuring a physiological first parameter as a function of a quantity of the energy aggregated over the cardiac cycles.

16. The method of claim 15, in which the collecting energy includes collecting energy from the cardiac pacing pulses issued from a cardiac function management device of the second device.

17. The method of claim 15, in which the collecting energy includes collecting energy using the first device located approximately 2 cm from a lead of the second device.

18. The method of claim 15, in which the measuring of the physiological first parameter includes measuring a tissue fluid accumulation.

19. The method of claim 15, in which the collecting energy includes capacitively storing the energy.

20. The method of claim 15, comprising counting cardiac pacing pulses delivered by the second device.

21. The method of claim 15, comprising wirelessly communicating with the second device.

22. The method of claim 21, in which the wirelessly communicating includes one or more of acoustic communication, inductive communication, and communication using the body as an electrical signal conductor.

23. A system comprising:

means for collecting energy using a first device, the energy collected from cardiac pacing pulses issued from an implantable second device, the first device being at least partially implanted at a first location within a body of a subject, the first location being different from a location of the second device, wherein the second device is physically separate from and unattached to the first device;

means for aggregating the energy collected from the cardiac pacing pulses over two or more cardiac cycles; and

means for measuring a physiological first parameter as a function of a quantity of the energy aggregated over the cardiac cycles.

24. The system of claim 23, wherein the second device includes a cardiac function management device.

25. The system of claim 23, wherein the first device is located approximately 2 cm from a lead of the second device.

26. The system of claim 23, wherein the means for measuring the physiological first parameter is configured to measure a tissue fluid accumulation.

27. The system of claim 23, wherein the means for collecting energy includes means for capacitively storing energy.

28. The system of claim 23, comprising means for counting cardiac pacing pulses delivered by the second device.

29. The system of claim 23, comprising means for wirelessly communicating with the second device.

30. The system of claim 29, wherein the means for wirelessly communicating is configured to use one or more of acoustic communication, inductive communication, and communication using the body as an electrical signal conductor.