Respiratory assistance apparatus and method

• US 7,861,710 B2
• Filed: 07/02/2007
• Issued: 01/04/2011
• Est. Priority Date: 06/30/2006
• Status: Active Grant

• Current Assignee: Pulmonx Corp.
• Original Assignee: Aeris Therapeutics, Inc.
• Inventors: Ingenito, Edward P.
• Primary Examiner(s): Douglas; Steven O
• Application Number:
  US11/824,942
• Publication Number:
  US 20080115787A1
• Time in Patent Office: 1,282 Days
• Field of Search: 128/200.24, 128/204.18, 128/204.21, 128/204.22, 128/205.13, 128/205.14
• US Class Current: 128/200.24
• CPC Class Codes: A61M 11/00 Sprayers or atomisers specially adapted for therapeutic purposes in general B05B; aerosol containers B65D83/14
• CPC Class Codes: A61M 11/008 by squeezing, e.g. using a flexible bottle or a bulb
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 16/0078 Breathing bags
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 16/107 in the inspiratory path
• CPC Class Codes: A61M 16/12 by mixing different gases
• CPC Class Codes: A61M 16/125 Diluting primary gas with ambient air
• CPC Class Codes: A61M 16/208 Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
• CPC Class Codes: A61M 16/209 Relief valves
• CPC Class Codes: A61M 2016/0027 pressure meter

Abstract

A hand-held apparatus that delivers pressurized breathing gas to the airway of a patient, thereby creating positive end expiratory pressure (PEEP) and reducing respiratory muscle fatigue. The apparatus includes a deformable reservoir, a breathing interface, and a pressure relief valve. The apparatus may include a means for creating fluid communication between the deformable reservoir and a source of pressurized breathing gas. The apparatus may also include an adjuster that allows a user to vary the pressure of the breathing gas contained in the deformable reservoir.

Claims

1. A handheld breathing assistance device to reduce respiratory muscle fatigue in a user with obstructive lung disease, the device comprising:

a deformable reservoir adaptable for containing pressurized breathing gas, at least a portion of the deformable reservoir being constructed and arranged to change shape to vary the volume of the pressurized breathing gas contained within the deformable reservoir;

a breathing interface for delivering pressurized breathing gas from said deformable reservoir to the airway of the user, the breathing interface being adaptable for fluid communication with the airway of the user, the breathing interface being further adaptable for fluid communication with the deformable reservoir;

at least one pressure relief valve to control the pressure of the gas contained in the deformable reservoir, the at least one pressure relief valve having an inlet and an outlet, the inlet being adaptable to be in fluid communication with the deformable reservoir, the outlet being adaptable to be in fluid communication with the atmosphere.

2. The device of claim 1 further comprising a means for creating fluid communication between the deformable reservoir and a source of the pressurized breathing gas.

3. The device of claim 2, wherein the means for creating fluid communication includes a threaded tube connector.

4. The device of claim 2, wherein the means for creating fluid communication includes a barbed tube connector.

5. The device of claim 2 further comprising a source of pressurized breathing gas.

6. The device of claim 5, wherein the source of pressurized breathing gas is a pressurized gas bottle.

7. The device of claim 5, wherein the source of pressurized breathing gas is a pump that increases the gas pressure within the deformable reservoir by drawing air from the atmosphere into the deformable reservoir.

8. The device of claim 7, wherein the pump is hand-operated.

9. The device of claim 1, wherein the deformable reservoir is expandable to a total volume between 10 to 750 ml greater than the total volume of said deformable reservoir under atmospheric pressure.

10. The device of claim 1, wherein the deformable reservoir includes a balloon.

11. The device of claim 1, wherein the deformable reservoir includes a diaphragm.

12. The device of claim 1 further comprising a means for adjusting the maximum expanded volume of the deformable reservoir.

13. The device of claim 1, wherein the breathing interface includes a mouthpiece couplable to the mouth of the user.

14. The device of claim 1, wherein the breathing interface includes a mask that fits over the nose and mouth of the user.

15. The device of claim 1, wherein the at least one pressure relief valve includes a one-way valve, said one-way valve preventing pressurized breathing gas from venting to the atmosphere when the pressurized breathing gas contained within the deformable reservoir is below a target venting pressure and venting the pressurized breathing gas to the atmosphere when the pressurized breathing gas contained within the deformable reservoir is equal to or above said target venting pressure.

16. The device of claim 1, further comprising an adjuster for varying the pressure of the gas contained in the deformable reservoir.

17. The device of claim 16, wherein said adjuster includes a spring and wherein the tension of the spring is varied to change the venting pressure of the gas contained in the deformable reservoir.

18. The device of claim 1, wherein the at least one pressure relief valve is positioned downstream of the breathing interface to facilitate venting expired air from the deformable reservoir.

19. The device of claim 1 further comprising a secondary orifice, the secondary orifice being adaptable to fluid communication with an external apparatus and further adaptable to fluid communication with the deformable reservoir.

20. The device of claim 19, wherein the external apparatus is a nebulizer.

21. The device of claim 19, wherein the external apparatus is a metered dose inhaler.

22. The device of claim 1 further comprising a multi-conduit mixing volume, the multi-conduit mixing volume including one conduit adaptable for connection to the deformable reservoir, a second conduit adaptable for connection the breathing interface, a third conduit adaptable for fluid communication with the source of pressurized gas, and a mixing volume adaptable to be in fluid communication with each conduit.

23. The device of claim 22, wherein the multi-conduit mixing volume includes a T-connector, the centerlines of the first and second conduits being axially aligned and the centerline of the third conduit being perpendicular to the axis of the centerlines of the first and second conduits.

24. The device of claim 22, wherein the multi-conduit mixing volume further includes a fourth conduit adaptable for detachably connecting a nebulizer, wherein the fourth conduit is adaptable to be in fluid communication with the mixing volume.

25. A method of reducing respiratory muscle fatigue comprising:

coupling the airway of a user in fluid communication with a breathing interface;

accepting pressurized gas into a deformable reservoir that is in fluid communication with the breathing interface;

allowing the deformable reservoir to expand to contain a desired volume of pressurized gas;

delivering the pressurized gas to the airway of the user through the breathing interface; and

venting the gas from the deformable reservoir when the pressure in the deformable reservoir exceeds a predetermined threshold.

26. The method of claim 25, wherein the source of pressurized gas is oxygen.

27. The method of claim 25, wherein the source of pressurized gas is a mixture of oxygen and at least one inert gas.

28. The method of claim 25 further comprising accepting expired gas from the user through the breathing interface.

29. The method of claim 25 further comprising coupling an external apparatus to a secondary opening, the secondary opening being adaptable to fluid communication with the deformable reservoir and further adaptable to fluid communication with the breathing interface.

30. The method of claim 29 wherein the external apparatus is a nebulizer.

31. The method of claim 29 wherein the external apparatus is a metered dose inhaler.

32. The method of claim 29 further comprising delivering the contents of the external apparatus to the user through the breathing interface.

33. The method of claim 25 further comprising varying the venting pressure of the gas stored in the deformable reservoir.

34. The method of claim 25 further comprising varying the maximum expanded volume of the deformable reservoir.