Apparatus and methods for delivering a stent into an ostium

• US 7,862,601 B2
• Filed: 05/23/2005
• Issued: 01/04/2011
• Est. Priority Date: 05/23/2005
• Status: Active Grant

• Current Assignee: Incept LLC
• Original Assignee: Incept LLC
• Inventors: Khosravi, Fred, Krolik, Jeff, Kim, Elliot, Sanati, Arashmidos
• Primary Examiner(s): Robert; Eduardo C
• Assistant Examiner(s): COLELLO, ERIN L
• Application Number:
  US11/136,266
• Publication Number:
  US 20060265041A1
• Time in Patent Office: 2,052 Days
• Field of Search: 623/1.11, 623/1.3, 623/1.31, 623/1.15, 623/1.12, 623/1.35, 604/103.05, 604/103.06, 604/103.07, 604/103.08, 60410101-10105
• US Class Current: 623/1.11
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/821 Ostial stents
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters

Abstract

Apparatus and methods are provided for delivering a stent into an ostium. The apparatus includes a catheter including a proximal end, a distal end, and proximal and distal balloons disposed adjacent one another on the distal end. The balloons are expandable independently of one another, and a stent is provided surrounding the balloons. During use, the distal end of the catheter is introduced into a main lumen, and the proximal balloon is inflated to flare a proximal portion of the stent. The distal end is then advanced into the ostium until the flared proximal portion contacts a wall of the main lumen surrounding the ostium. The distal balloon is inflated to expand a distal portion of the stent, e.g., to dilate a lesion within the branch and/or ostium. Thereafter, the balloons are collapsed, and the apparatus is withdrawn, leaving the stent within the ostium.

Claims

1. A method for implanting a prosthesis within an ostium extending from a main lumen into a branch lumen using an elongate member comprising first and second expandable members on a distal end of the elongate member, the prosthesis comprising first and second portions surrounding the first and second expandable members, respectively, the first portion having a length greater than the second portion and comprising material that requires greater force to expand than the second portion, the method comprising:

directing the distal end of the elongate member into the main lumen with the first and second portions in a contracted condition;

expanding the second expandable member to cause the second portion of the prosthesis to flare radially outwardly from the first portion within the main lumen while the first portion of the prosthesis remains in the contracted condition;

after expanding the second expandable member, directing the distal end into the branch lumen until the flared second portion contacts a wall of the main lumen surrounding the ostium and the first portion is disposed within the branch lumen;

after directing the distal end into the ostium, expanding the first expandable member to expand the first portion of the prosthesis to contact a wall of the branch lumen;

collapsing the first and second expandable members; and

withdrawing the elongate member from the branch and main lumens, leaving the prosthesis with the first portion expanded within the branch lumen and the second portion contacting the wall of the main lumen surrounding the ostium.

2. The method of claim 1, wherein the first portion is expanded to dilate the branch lumen.

3. The method of claim 1, wherein the first portion is constrained while the second expandable member is expanded, and wherein the constraint is removed before expanding the first expandable member.

4. The method of claim 1, wherein the second portion is deformed as the second expandable member is expanded such that an acute angle is defined between the first and second portions.

5. The method of claim 1, wherein the second portion is deformed as the second expandable member is expanded such that an obtuse angle is defined between the first and second portions.

6. The method of claim 1, wherein the second portion is at least partially deformed as the distal end of the elongate member is directed into the branch lumen such that the second portion conforms at least partially to a shape of the wall of the main lumen surrounding the ostium.

7. The method of claim 1, wherein an internal pressure necessary to expand the second expandable member is less than an internal pressure necessary to expand the first expandable member.

8. The method of claim 1, wherein an internal pressure necessary to expand the first expandable member is less than an internal pressure necessary to expand the second expandable member.

9. The method of claim 1, further comprising expanding the second expandable member further after expanding the first expandable member.

10. The method of claim 9, wherein expanding the second expandable member further causes the second portion of the prosthesis to conform to the contour of the ostium.

11. The method of claim 9, wherein expanding the second expandable member further causes the prosthesis to dilate the ostium.

12. A method for implanting a prosthesis within an ostium extending from a main lumen into a branch lumen using an elongate member comprising first and second expandable members on a distal end of the elongate member, the prosthesis comprising first and second portions surrounding the first and second expandable members, respectively, the first portion having a length greater than the second portion and comprising material that requires greater force to expand than the second portion, the method comprising:

directing the distal end of the elongate member into the main lumen with the first and second portions in a contracted condition;

expanding the second expandable member to cause the second portion of the prosthesis to flare radially outwardly from the first portion within the main lumen while the first portion of the prosthesis remains in the contracted condition;

after expanding the second expandable member, directing the distal end into the ostium with sufficient force to cause the expanded second portion to engage a wall of the main lumen surrounding the ostium with the first portion disposed within the branch lumen;

after directing the distal end into the ostium, expanding the first expandable member to expand the first portion of the prosthesis to contact a wall of the branch lumen;

after expanding the first expandable member to expand the first portion of the prosthesis, expanding the second expandable member further to expand the second portion of the prosthesis further; and

collapsing the first and second expandable members.

13. The method of claim 12, wherein the expanded second portion of the prosthesis is deformed to at least partially conform with the ostium when the distal end is directed into the ostium.

14. The method of claim 12, further comprising releasing at least a portion of the prosthesis such that the prosthesis at least partially expands resiliently before expanding at least one of the first and second expandable members to further expand the prosthesis.

15. The method of claim 12, wherein expanding the second expandable member further causes the second portion of the prosthesis to conform to the contour of the ostium.

16. The method of claim 12, wherein expanding the second expandable member further causes the prosthesis to dilate the ostium.