Particle dispersion device for nasal delivery

• US 7,866,316 B2
• Filed: 09/14/2006
• Issued: 01/11/2011
• Est. Priority Date: 09/28/2001
• Status: Active Grant

• Current Assignee: Savine Therapeutics Pty
• Original Assignee: Kurve Technology, Inc.
• Inventors: Giroux, Mark
• Primary Examiner(s): Douglas; Steven O
• Application Number:
  US11/522,495
• Publication Number:
  US 20070068514A1
• Time in Patent Office: 1,580 Days
• Field of Search: 128/200.14, 128/200.18, 128/203.15, 128/207.18
• US Class Current: 128/203.15
• CPC Class Codes: A61M 11/00 Sprayers or atomisers specially adapted for therapeutic purposes in general B05B; aerosol containers B65D83/14
• CPC Class Codes: A61M 11/001 Particle size control
• CPC Class Codes: A61M 15/0008 rotating by airflow
• CPC Class Codes: A61M 15/0028 using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
• CPC Class Codes: A61M 15/0086 Inhalation chambers
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 2206/16 Rotating swirling helical flow, e.g. by tangential inflows
• CPC Class Codes: A61M 2210/0618 Nose

Abstract

A nebulizer and a method of breathing using the nebulizer is described. The nebulizer and breathing techniques are capable of delivering medicament into the sinus cavity of a user.

Claims

1. A particle dispersion chamber comprising:

a housing having an external surface, a particle entry end, an output opening, and an internal channel between the particle input end and the output opening, the channel generally defining an axis and a forward direction toward the output opening; and

a plurality of directional fluid outputs within and communicating with the internal channel, directing output at an acute forward angle with respect to the channel axis and output opening, wherein the fluid outputs, when fluid flows therefrom, are operative to impart a vortical flow the aerosolized particles exiting the output opening, and wherein the internal channel has a substantially continuous cross-sectional area from the particle input end of the housing and including a location of a fluid output within the internal channel to, and including, the output opening.

2. The particle dispersal chamber of claim 1, wherein the fluid outputs are positioned randomly along the internal channel.

3. The particle dispersion chamber of claim 1, wherein the fluid outputs are positioned in a symmetrical array along the internal channel.

4. The particle dispersion chamber of claim 1, wherein the fluid outputs are jets.

5. The particle dispersion chamber of claim 1, further comprising a dispersion blade located within the internal channel.

6. The particle dispersion chamber of claim 5, wherein the dispersion blade is solid.

7. The particle dispersion chamber of claim 5, wherein the dispersion blade is netting.

8. The particle dispersion chamber of claim 1, further comprising a baffle located within the internal channel.

9. The particle dispersion chamber of claim 8, wherein the baffle is helical shape.

10. The particle dispersion chamber of claim 1, further comprising an inhaler having a mouthpiece, the mouthpiece associated with the particle dispersion chamber.

11. The particle dispersion chamber of claim 1, further comprising a nasal spray inhaler having an actuator, the actuator associated with the particle dispersion chamber.

12. The particle dispersion chamber of claim 1, further comprising a dry powder inhaler having an mouthpiece, the mouthpiece associated with the particle dispersion chamber.

13. The particle dispersion chamber of claim 1, wherein the fluid outputs are outputs for a fluid selected from the group consisting of air, compressed air, gas, compressed gas and combinations thereof.

14. The particle dispersion chamber of claim 1, comprising:

a housing having an external surface, a particle entry end, an output opening, and an internal channel between the particle input end and the output opening, the channel generally defining an axis and a forward direction toward the output opening; and

a plurality of directional fluid outputs within and communicating with the internal channel, directing output at an acute forward angle with respect to the channel axis and output opening, wherein the fluid outputs, when fluid flows therefrom, are operative to impart a vortical flow the aerosolized particles exiting the output opening, and wherein the internal channel has a substantially constant cross-sectional area from the particle input end of the housing and including a location of a fluid output within the internal channel to, and including, the output opening.