Inhalation device

• US 7,866,317 B2
• Filed: 03/03/2006
• Issued: 01/11/2011
• Est. Priority Date: 03/08/2005
• Status: Active Grant

• Current Assignee: Vectura GmbH (Vectura Group Ltd.)
• Original Assignee: Activaero GmbH
• Inventors: Wenker, Andreas, Scheuch, Gerhard, Muellinger, Bernhard, Koerber, Dorothee
• Primary Examiner(s): Douglas; Steven O
• Application Number:
  US11/367,618
• Publication Number:
  US 20060201499A1
• Time in Patent Office: 1,775 Days
• Field of Search: 128/204.18, 128/204.21, 128/204.23
• US Class Current: 128/204.18
• CPC Class Codes: A61M 11/06 of the injector type
• CPC Class Codes: A61M 16/0063 Compressors
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/107 in the inspiratory path
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2205/42 Reducing noise
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/60 with identification means
• CPC Class Codes: A61M 2205/707 Testing of filters for clogging

Abstract

An inhalation device may include a control and an air pump that is connected to the control. The air pump is controlled by the control such that the air pump supplies an inhalation flow, or inhalation volume or both according to a predetermined time course to a nebulizer connected to the air pump. The inhalation flow, inhalation volume or both is controlled by controlling the air pump, rather than by using valves.

Claims

1. An inhalation device comprising

a control;

an air pump; and

a downstream nebulizer, the air pump connected to the downstream nebulizer and connected to the control, wherein the control controls the air pump by voltage, or pulse-width modulation or both, such that it supplies an inhalation flow, or an inhalation volume or both, according to a predetermined time course to the nebulizer.

2. The inhalation device according to claim 1 further comprising a mouthpiece associated with the nebulizer.

3. The inhalation device according to claim 1 wherein the control of the air pump is carried out via the control depending on patient-individual lung function parameters.

4. The inhalation device according to claim 3 wherein the patient-individual lung function parameters are inhalation flow, or inhalation volume or both.

5. The inhalation device according to claim 3 wherein the control evaluates, on the basis of the patient-individual lung function parameters, the control voltage for the air pump which is necessary for obtaining a constant inhalation flow Q_target individually determined for the patient.

6. The inhalation device according to claim 1 wherein the control performs a correction of the control voltage, or the pulse-width modulation or both when a measured actual inhalation flow Q_measurement differs from a predetermined inhalation flow Q_target.

7. The inhalation device according to claim 6 wherein a flow-voltage characteristic is used dependent on the predetermined inhalation flow Q_target and the measured actual inhalation flow Q_measurement for a correction of the control voltage of the air pump.

8. The inhalation device according to claim 7 wherein the flow-voltage characteristic is further dependent on a cycle number of the specific air pump.

9. The inhalation device according to claim 1 wherein the control considers a counter-pressure generated by the patient.

10. The inhalation device according to claim 8 wherein the flow-voltage characteristic of the air pump is at first individually measured and afterwards approximated mathematically.

11. The inhalation device according to claim 1 wherein the control comprises a control for the drive of the air pump, a processing unit and a memory.

12. The inhalation device according to claim 11 wherein data representing patient-individual lung function parameters is stored in the memory.

13. The inhalation device according to claim 1 further comprising a reader to read external data carriers.

14. The inhalation device according to claim 13 wherein the reader is a SmartCard device reader and the external data carrier is a SmartCard device on which data are stored representing the patient-individual lung function parameters.

15. The inhalation device according to claim 1 further comprising a display unit and an input unit.

16. The inhalation device according to claim 1 further comprising a safety valve arranged downstream from the air pump.

17. The inhalation device according to claim 1 further comprising a pressure sensor arranged downstream from the air pump.

18. The inhalation device, according to claim 1 comprising an air pump and a pressure sensor for recognising the start of an inhalation process, wherein any or all of a pharmaceutical to be inhaled, an inhalation flow, or an inhalation volume can be individually set by the user, and wherein upon recognition of a first inhalation process by the pressure sensor, the individual parameters are set and the air pump is activated.

19. The inhalation device according to claim 18 wherein after the first inhalation or an inhalation stop, the user may optionally continue with the previous parameters or perform a reset of the parameters.

20. The inhalation device according to claim 1 wherein the air pump is a compressor or turbine.

21. The inhalation device according to claim 1 wherein an inhalation flow, or an inhalation volume or both, are kept basically constant during the predetermined time course.

22. The inhalation device according to claim 1 wherein an inhalation flow, or an inhalation volume or both, assume different levels during the predetermined time course.

23. The inhalation device according to claim 22 wherein the inhalation flow or the inhalation volume or both are kept basically constant.

24. A method for regulating an inhalation flow provided by an inhalation device according to claim 1 to a basically constant value by controlling the control voltage of the air pump of the inhalation device.

25. The method according to claim 24 wherein the control of the air pump takes place depending on patient-individual lung function parameters.

26. The method according to claim 25 wherein the patient-individual lung function parameters are inhalation flow, or inhalation volume or both.

27. The method according to claim 25 wherein on a basis of the patient-individual lung function parameters the control voltage for the air pump is determined to obtain a constant inhalation flow Q_target individually predetermined for the patient.

28. The method according to claim 27 wherein a correction of the control voltage is performed when a measured actual inhalation flow Q_measurement differs from the predetermined inhalation flow Q_target.

29. The method according to claim 28 wherein a flow-voltage characteristic depending on the predetermined inhalation flow Q_target and the measured actual inhalation flow Q_measurement is used to correct the control voltage of the air pump.

30. The method according to claim 29 wherein the flow-voltage characteristic of the air pump is at first individually determined by measurements and afterwards approximated mathematically.