Method and apparatus for non-invasively measuring hemodynamic parameters using parametrics
First Claim
1. Apparatus adapted to measure the blood pressure of a living subject, comprising:
- a pressure sensor adapted to generate a signal relating to the pressure applied to a blood vessel of said subject, said applied pressure being applied at least in part by tissue interposed between said sensor and a blood vessel of said subject;
a bias element disposed proximate to said pressure sensor and adapted to mitigate the effects of said tissue on said applied pressure; and
a digital processor configured to scale said signal using a scaling factor, said scaling factor comprising said subject'"'"'s weight divided by said subject'"'"'s height squared.
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Abstract
An improved method and apparatus for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. In one aspect, the invention comprises a method of measuring a hemodynamic parameter (e.g., arterial blood pressure) by applanating or compressing portions of tissue proximate to the blood vessel of concern until a desired condition is achieved, and then measuring the hemodynamic parameter. Such applanation effectively mitigates transfer and other losses created by the tissue proximate to the blood vessel, thereby facilitating accurate and robust tonometric measurement. An algorithm adapted to maintain optimal levels of applanation is also described. Methods and apparatus for scaling such hemodynamic parameter measurements based on subject physiology, and providing treatment to the subject based on the measured parameters, are also disclosed.
113 Citations
25 Claims
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1. Apparatus adapted to measure the blood pressure of a living subject, comprising:
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a pressure sensor adapted to generate a signal relating to the pressure applied to a blood vessel of said subject, said applied pressure being applied at least in part by tissue interposed between said sensor and a blood vessel of said subject; a bias element disposed proximate to said pressure sensor and adapted to mitigate the effects of said tissue on said applied pressure; and a digital processor configured to scale said signal using a scaling factor, said scaling factor comprising said subject'"'"'s weight divided by said subject'"'"'s height squared. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method of measuring the blood pressure of a living subject, comprising:
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utilizing a pressure sensor to applanate a blood vessel of said living subject; utilizing said pressure sensor to measure a plurality of pressure values of said applanated blood vessel; determining a first physiological parameter of said living subject; determining a BMI of said living subject; deriving a scaling factor based at least in part on said first physiological parameter and said BMI; scaling said plurality of pressure values using said scaling factor, said act of scaling comprising using at least one algorithm run on a processor associated with said pressure sensor; and utilizing said scaled pressure values to generate a blood pressure value for presentation to a user. - View Dependent Claims (8, 9, 10, 11)
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12. Apparatus for measuring the blood pressure of a living subject, comprising:
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a first means for generating a signal relating to the pressure in a blood vessel of said subject, said signal being affected at least in part by tissue interposed between said first means and a blood vessel of said subject; a second means for mitigating the effects of said tissue on said signal, said first and second means being disposed proximate to one another; and a third means for scaling said signal using a scaling factor, said scaling factor comprising a weight (w) of said subject divided by a height (h) of said subject squared (w/h2). - View Dependent Claims (13, 14, 15, 16, 17)
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18. A method of measuring the blood pressure of a living subject, comprising:
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utilizing a pressure sensor to applanate a blood vessel of said living subject; utilizing said pressure sensor to obtain a plurality of pressure values associated with said applanated blood vessel; determining a body mass index (BMI) of said living subject; deriving a scaling factor based at least in part on said BMI; scaling said plurality of pressure values using said scaling factor, said act of scaling comprising using at least one algorithm run on a processor associated with said pressure sensor; and utilizing said scaled pressure values to generate a blood pressure value for presentation to a user. - View Dependent Claims (19, 20, 21)
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22. A method of measuring the blood pressure of a living subject, comprising:
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applanating a blood vessel of said living subject and using a pressure sensor to obtain a plurality of pressure values associated with said applanated blood vessel; determining a body mass index (BMI) of said living subject; deriving a scaling factor based at least in part on said BMI; scaling said plurality of pressure values using said scaling factor, said act of scaling comprising using at least one algorithm run on a processor associated with said pressure sensor; and utilizing said scaled pressure values to generate a blood pressure value for presentation to a user. - View Dependent Claims (23, 24, 25)
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Specification