Implantable pump with adjustable flow rate

• US 7,867,203 B2
• Filed: 03/04/2008
• Issued: 01/11/2011
• Est. Priority Date: 09/05/2003
• Status: Expired due to Fees

• Current Assignee: Codman & Shurtleff Incorporated (Johnson & Johnson)
• Original Assignee: Codman & Shurtleff Incorporated (Johnson & Johnson)
• Inventors: MacBride, Douglas, Rosenberg, Meir
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): Price; Nathan R
• Application Number:
  US12/042,037
• Publication Number:
  US 20080154215A1
• Time in Patent Office: 1,043 Days
• Field of Search: 604/247, 604/250, 6048901-8921, 417/44.9, 417/132, 137/625.12, 137/863, 251/5
• US Class Current: 604/246
• CPC Class Codes: A61M 2205/3507 with implanted devices, e.g. external control
• CPC Class Codes: A61M 39/227 Valves actuated by a secondary fluid, e.g. hydraulically or pneumatically actuated valves
• CPC Class Codes: A61M 5/141 with capillaries for restricting fluid flow
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16813 by controlling the degree of opening of the flow line
• CPC Class Codes: F16K 7/17 the diaphragm being actuated by fluid pressure

Abstract

A valve that is adapted to control the flow rate of fluid flow from an implantable pump or other fluid delivery device is provided. In general, the valve includes a multi-lumen member that is adapted to receive fluid-flow therethrough, and a restrictor member that is coupled to the multi-lumen member such that the restrictor member is effective to selectively restrict at least a portion of one or more lumens in the multi-lumen member to thereby adjust the flow rate of fluid flowing through the multi-lumen member. The valve can be built into an implantable drug pump to control fluid flow exiting the pump, or alternatively the valve can disposed within a catheter or otherwise coupled to an outlet port in an implantable drug pump to control the flow rate of fluid exiting the drug pump.

Claims

1. A valve adapted to control the flow rate of fluid flow from an implantable pump, comprising:

a multi-lumen member disposed within a housing and adapted to receive fluid-flow therethrough between a first end coupled to an inlet and a second end coupled to an outlet; and

a restrictor member that prevents fluid that is flowing from the inlet to the outlet from flowing through the restrictor member without blocking the inlet, the restrictor member extending across the housing and sealed around a perimeter of the housing, and the restrictor member being coupled to the multi-lumen member such that the restrictor member is effective to selectively restrict at least a portion of one or more lumens in the multi-lumen member to thereby adjust the flow rate of fluid flowing through the multi-lumen member.

2. The valve of claim 1, wherein the multi-lumen member comprises a multi-lumen capillary tube.

3. The valve of claim 2, wherein the inlet coupled to the first end of the multi-lumen member comprises an inlet port for receiving fluid flow from an implantable pump, and the outlet coupled to the second end of the multi-lumen member comprises an outlet port for delivering fluid to a fluid-delivery catheter.

4. The valve of claim 3, wherein the restrictor member comprises a flexible membrane disposed adjacent to one of the first end or the second end of the capillary tube, the flexible membrane being effective to selectively restrict at least a portion of one or more lumens in the capillary tube.

5. The valve of claim 4, further comprising an actuator mechanism for applying pressure to the flexible membrane to selectively restrict at least a portion of one or more lumens in the capillary tube.

6. The valve of claim 5, wherein the actuator mechanism comprises a mechanical or electromechanical member.

7. The valve of claim 4, wherein the flexible membrane is expandable to selectively restrict at least a portion of one or more lumens in the capillary tube.

8. The valve of claim 4, wherein the flexible membrane is coupled to the housing to form a balloon-like structure such that the flexible membrane is inflatable to selectively restrict at least a portion of one or more lumens in the capillary tube.

9. The valve of claim 8, further comprising a hydraulic pump coupled to the flexible membrane and effective to at least one of inflate or deflate the flexible membrane.

10. The valve of claim 9, further comprising an actuator mechanism coupled to the hydraulic pump for selectively actuating the hydraulic pump, the actuator mechanism being operable by telemetry.

11. The valve of claim 1, wherein the multi-lumen member includes two or more lumens that each extend from the first end to the second end.

12. The valve of claim 1, wherein the first end and the second end of the multi-lumen member are opposed.

13. A method for controlling the flow rate of fluid being delivered to a patient from an implantable pump, comprising:

providing a valve in fluid communication with a reservoir formed in an implantable pump, the valve including a multi-lumen member disposed within a valve housing and coupled to a restrictor member extending across the valve housing and sealed around a perimeter of the housing, the restrictor member preventing fluid flowing from an inlet to an outlet from flowing through the restrictor member without blocking the inlet, and selectively restricting at least a portion of one or more lumens in the multi-lumen member to thereby adjust the flow rate of fluid flowing from the reservoir between a first end of the multi-lumen member coupled to the inlet and a second end of the multi-lumen member coupled to the outlet; and

actuating the restrictor member to selectively restrict at least a portion of one or more lumens to thereby adjust the flow rate of fluid flowing from the reservoir.

14. The method of claim 13, wherein the inlet coupled to the first end of the multi-lumen member comprises an inlet port for receiving fluid flow from an implantable pump, and the outlet coupled to the second end of the multi-lumen member comprises an outlet port for delivering fluid to a fluid-delivery catheter.

15. The method of claim 13, wherein the restrictor member comprises a flexible membrane disposed adjacent to one of the first end or the second end of the multi-lumen member, the flexible membrane being effective to selectively restrict at least a portion of one or more lumens in the multi-lumen member.

16. The method of claim 15, further comprising an actuator mechanism for applying pressure to the flexible membrane to selectively restrict at least a portion of one or more lumens in the multi-lumen member.

17. The method of claim 16, wherein the actuator mechanism comprises a mechanical or electromechanical member.

18. The method of claim 15, wherein the flexible membrane is expandable to selectively restrict at least a portion of one or more lumens in the multi-lumen member.

19. The method of claim 15, wherein the flexible membrane is coupled to the valve housing to form a balloon-like structure such that the flexible membrane is inflatable to selectively restrict at least a portion of one or more lumens in the multi-lumen member.

20. The method of claim 19, further comprising a hydraulic pump coupled to the flexible membrane and effective to at least one of inflate or deflate the flexible membrane.

21. The method of claim 20, further comprising an actuator mechanism coupled to the hydraulic pump for selectively actuating the hydraulic pump, wherein the actuator mechanism is operable by telemetry.