Spinal fusion implant and related methods

• US 7,867,277 B1
• Filed: 07/17/2006
• Issued: 01/11/2011
• Est. Priority Date: 07/15/2005
• Status: Active Grant

• Current Assignee: Nuvasive Incorporated
• Original Assignee: Nuvasive Incorporated
• Inventors: Tohmeh, Antoine G.
• Primary Examiner(s): Robert; Eduardo C
• Assistant Examiner(s): HOFFMAN, MARY C
• Application Number:
  US11/488,744
• Time in Patent Office: 1,639 Days
• Field of Search: 606/61, 623 1711- 1716
• US Class Current: 623/17.11
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2/4455 for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages intervertebral discs A61F2/442
• CPC Class Codes: A61F 2/46 Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
• CPC Class Codes: A61F 2002/2817 Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
• CPC Class Codes: A61F 2002/2835 Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
• CPC Class Codes: A61F 2002/3008 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2002/30593 hollow
• CPC Class Codes: A61F 2002/30616 Sets comprising a plurality of prosthetic parts of different sizes or orientations
• CPC Class Codes: A61F 2002/30785 parallel
• CPC Class Codes: A61F 2002/30841 Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
• CPC Class Codes: A61F 2002/30892 parallel
• CPC Class Codes: A61F 2002/448 comprising multiple adjacent spinal implants within the same intervertebral space or within the same vertebra, e.g. comprising two adjacent spinal implants
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2310/00179 Ceramics or ceramic-like structures

Abstract

A spinal fusion implant of non-bone construction to be introduced into any variety of spinal target sites. The spinal fusion implant of the present invention includes a top surface, a bottom surface, first and second lateral sides, a proximal (posterior) end and a distal (anterior) end. The spinal fusion implant of the present invention may be used to provide temporary or permanent fixation within an orthopedic target site. To do so, the spinal fusion implant may be introduced into a disc space while locked to a surgical insertion instrument and thereafter employed in the proper orientation and released. Once deposited in the disc space, the spinal fusion implant of the present invention effects spinal fusion over time as the natural healing process integrates and binds the implant.

Claims

1. A method of fusing adjacent first and second vertebral bodies separated by an intervertebral space, each vertebral body having a cancellous bone interior bounded by a cortical bone exterior wall, and a generously curved anterior portion and a slightly curved posterior portion, said posterior portion adjacent to a spinal canal, and a midline extending through said anterior and posterior portions, said method comprising:

inserting a spinal fusion implant into the intervertebral space, the spinal fusion implant having opposing first and second engagement surfaces, and opposing first and second lateral surfaces extending along a longitudinal axis, said first and second engagement surfaces situated at generally right angles to said first and second lateral surfaces, a proximal surface extending between said first and second lateral surfaces and said first and second engagement surfaces, said first lateral surface being longer than said second lateral surface such that said proximal surface is non-perpendicular to said longitudinal axis, and at least one radiographic marker situated between said first and second engagement surfaces, and wherein said spinal fusion implant is inserted such that said proximal surface is positioned on a first side of said midline and a distal surface is positioned on a second side of said midline such that said longitudinal axis is non-parallel to said midline and said proximal surface is generally perpendicular to said midline, said first and second engagement surfaces immediately adjacent said distal surface being in contact with an anterior portion of said cortical bone wall, said first and second engagement surfaces immediately adjacent said proximal surface being in contact with a posterior portion of said cortical bone wall without said proximal surface encroaching into said spinal canal,

wherein said step of inserting said spinal fusion implant includes the step of inserting said spinal fusion implant into the intervertebral space such that said first and second lateral surfaces are facing said first and second vertebral bodies, and thereafter rotating said spinal fusion implant ninety degrees such that said first and second engagement surfaces engage said first and second vertebral bodies.

2. The method of claim 1, wherein said distal surface of said implant is adapted to extend between said cortical walls of said anterior portions of said first and second vertebral bodies.

3. The method of claim 1, wherein said at least one radiographic marker is located approximate at least one of said proximal surface and distal surface.

4. The method of claim 1, wherein a plurality of radiographic markers are provided approximate said proximal surface.

5. The method of claim 4, wherein a first of said radiographic markers is positioned approximate the intersection of said proximal surface and said lateral surface.

6. The method of claim 5, wherein a second of said radiographic markers is positioned approximate the intersection of said proximal surface and said second lateral surface.

7. The method of claim 3, wherein said radiographic marker comprises radiopaque material.

8. The method of claim 7, wherein said radiopaque material comprises at least one of a metal, ceramic, and polymer.

9. The method of claim 1, wherein at least one of said first and second engagement surfaces is generally tapered from said distal surface toward said proximal surface.

10. The method of claim 9, wherein said anti-migration feature comprises a plurality of ridges.

11. The method of claim 1, wherein at least one of said first and second engagement surfaces is generally tapered from said distal surface toward said proximal surface.

12. The method of claim 11, wherein said at least one of said first and second engagement surfaces is tapered at a measured angle ranging between 6 and 10 degrees.

13. The method of claim 1, wherein said first and second engagement surfaces are at least one of generally planar, generally convex, and generally concave.

14. The method of claim 1, said implant further comprising a central aperture extending through said implant between said first and second engagement surfaces.

15. The method of claim 1, said implant further comprising at least one lateral aperture extending through said implant between said first and second lateral surfaces.

16. The method of claim 1, wherein said implant comprises a first tapered surface extending between said distal surface and said first lateral surface and second tapered surface extending between said distal surface and said second lateral surface.

17. The method of claim 16, wherein said implant comprises a third tapered surface extending between said distal surface and said second engagement surface.

18. The method of claim 1, wherein said implant is made of at least one of poly-ether-ether-ketone, poly-ether-ketone-ketone, ceramic, and metal.

19. A method of fusing adjacent first and second vertebral bodies, each vertebral body having a cancellous bone interior bounded by a cortical bone exterior wall, and a generously curved anterior portion and a slightly curved posterior portion, said posterior portion adjacent to a spinal canal, and a midline extending through said anterior and posterior portions, said method comprising:

inserting a spinal fusion implant into an intervertebral space between said first and second vertebral bodies, said implant having opposing first and second engagement surfaces and opposing first and second lateral surfaces extending along a longitudinal axis, said first and second engagement surfaces situated at generally right angles to said first and second lateral surfaces, a proximal surface extending between said first and second lateral surfaces and said first and second engagement surfaces, said first lateral surface being longer than said second lateral surface such that said proximal surface is non-perpendicular to said longitudinal axis, said spinal fusion implant further including a first radiographic marker situated between said first and second engagement surfaces and positioned such that it is centrally located near a distal surface, a second radiographic marker situated between said first and second engagement surfaces and positioned near a first proximal corner, and a third radiographic marker situated between said first and second engagement surfaces and positioned near a second proximal corner, said first proximal corner being defined by the intersecting of said first lateral surface and said proximal surface so that when viewed laterally to said longitudinal axis said second and third radiographic markers are not aligned, said spinal fusion implant being inserted into the intervertebral space such that said proximal surface is positioned on a first side of said midline and said distal surface is positioned on a second side of said midline such that said longitudinal axis is non-parallel to said midline; and

viewing said spinal fusion implant radiographically from a lateral direction relative to said midline to determine if correct placement of spinal fusion implant has been achieved by observing said radiographic markers, wherein correct placement of said spinal fusion implant is accomplished when said second and third radiographic markers are aligned.