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Immunoglobulin fusion proteins

  • US 7,867,491 B2
  • Filed: 05/30/2008
  • Issued: 01/11/2011
  • Est. Priority Date: 05/30/2007
  • Status: Active Grant
First Claim
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1. A polypeptide represented by the following formula:


  • N′



    (Z1)p

    Y—

    Z2—

    Z3—

    Z4—

    C′

    wherein N′

    is the N-terminus and C′

    is the C-terminus of the polypeptide,Z1 is an amino acid sequence consisting of the amino acid residues at positions 90 to 98 of SEQ ID NO;

    14;

    Y is an amino acid sequence consisting of 5 or more consecutive amino acid residues from the C-terminus at positions 99 to 162 of SEQ ID NO;

    14;

    Z2 is an amino acid sequence consisting of the amino acid residues at positions 163 to 170 of SEQ ID NO;

    14;

    Z3 is an amino acid sequence consisting of the amino acid residues at positions 121 to 220 of SEQ ID NO;

    13;

    Z4 is an amino acid sequence consisting of the amino acid residues at positions 221 to 327 of SEQ ID NO;

    13; and

    p is an integer of 0 or 1.

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