Apparatus for magnetically deployable catheter with MOSFET sensor and method for mapping and ablation

• US 7,869,854 B2
• Filed: 02/23/2006
• Issued: 01/11/2011
• Est. Priority Date: 02/23/2006
• Status: Expired due to Fees

• Current Assignee: Neuro-Kinesis Corporation
• Original Assignee: Magnetecs Incorporated
• Inventors: Gang, Eli, Shachar, Yehoshua, Farkas, Laszlo
• Primary Examiner(s): Manuel; George
• Application Number:
  US11/362,542
• Publication Number:
  US 20070197891A1
• Time in Patent Office: 1,783 Days
• Field of Search: 606/34, 606/32, 600/393, 600/374, 600/508, 600/509
• US Class Current: 600/374
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00026 Conductivity or impedance, e.g. of tissue
• CPC Class Codes: A61B 2017/0011 piezoelectric
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2018/1467 using more than two electrodes on a single probe
• CPC Class Codes: A61B 2018/183 characterised by the type of antenna
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2034/301 for introducing or steering flexible instruments inserted into the body, e.g. catheters or endoscopes
• CPC Class Codes: A61B 2034/742 Joysticks
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 34/73 Manipulators for magnetic surgery
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/33 specially adapted for cooperation with other devices
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence
• CPC Class Codes: A61B 6/541 involving acquisition triggered by a physiological signal
• CPC Class Codes: A61B 8/543 involving acquisition triggered by a physiological signal

Abstract

A mapping and ablation catheter is described. In one embodiment, the catheter includes a MOSFET sensor array that provides better fidelity of the signal measurements as well as data collection and reduces the error generated by spatial distribution of the isotropic and anisotropic wavefronts. In one embodiment, the system maps the change in potential in the vicinity of an activation wavefront. In one embodiment, the mapping system tracks the spread of excitation in the heart, with properties such as propagation velocity changes. In one embodiment, during measurement, the manifold carrying the sensor array expands from a closed position state to a deployable open state. Spatial variation of the electrical potential is captured by the system'"'"'s ability to occupy the same three-dimensional coordinate set for repeated measurements of the desired site. In one embodiment, an interpolation algorithm tracks the electrogram data points to produce a map relative to the electrocardiogram data.

Claims

1. A system for mapping endocardial tissue, said system, comprising:

a catheter having a catheter distal end for insertion into a patient;

a plurality of sensors associated with said distal end, wherein said plurality of sensors are configured to obtain measurements of electrical potential of endocardial tissue in contact with said sensors such that current flow in each sensor is proportional to said electrical potential of said endocardial tissue, wherein each of the plurality of sensors comprise;

a housing in contact with said tissue;

a transistor with a first P-N junction between a first gate junction and a source terminal and between said gate junction and a drain terminal, wherein said source terminal and drain terminal are connected to said housing in contact with said endocardial tissue such that said gate junction assumes said potential of said endocardial tissue;

a computer accessible memory that stores said measurements of said electrical potential of said endocardial tissue obtained by said plurality of sensors over a time duration; and

one or more computer processors that correlate said measurements of said electrical potential of said endocardial tissue with a location of said distal end of said catheter to create an endocardial map of said tissue.

2. The system of claim 1, said distal end of said catheter further comprising a magnet.

3. The system of claim 2, further comprising a deployment mechanism proximate to said catheter distal end and configured to increase a separation between a distal end of a first deployable member and a distal end of a second deployable member.

4. The system of claim 2, wherein said deployment mechanism further comprises a coil that is configured to increase said separation between said distal end of said first deployable member and said distal end of said second deployable member when current is provided to said coil.

5. The system of claim 1, wherein said said PN junction is further in communication with a second gate.

6. The system of claim 1, wherein P material of said first PN junction is electrically closer to said tissue than N material and said second electrical contact comprises a second PN junction oriented such that N material of said second PN junction is electrically closer to said tissue than P material.

7. The system of claim 1, further comprising a second PN junction, wherein an said first and second PN junctions are configured with opposite polarity.

8. The system of claim 1, further comprising an antenna in communication with at least one of said plurality of sensors.

9. The system of claim 1, wherein said catheter comprises a lumen.

10. The system of claim 1, further comprising an operator interface unit.

11. The system of claim 1, further comprising:

a magnetic field source for generating a magnetic field, said magnetic field source comprising a first coil corresponding to a first magnetic pole and a second coil corresponding to a second magnetic pole, wherein said first magnetic pole is moveable with respect to said second magnetic pole; and

a system controller for controlling said magnetic field source to control a movement of said catheter distal end, said distal end responsive to said magnetic field, said controller configured to control a current in said first coil, a current in said second coil, and a position of said first pole with respect to said second pole.

12. The system of claim 11, said system controller comprises a closed-loop feedback servo system.

13. The system of claim 11, wherein one or more magnetic field sensors are used to measure said magnetic field.

14. The system of claim 11, said distal end comprising one or more magnetic field sensors.

15. The system of claim 11, said distal end comprising one or more magnetic field sensors for providing sensor data to said system controller.

16. The system of claim 11, wherein said servo system comprises a correction factor that compensates for a dynamic position of an organ, thereby offsetting a response of said distal end of said catheter to said magnetic field such that said distal end moves in substantial unison with said organ.

17. The system of claim 16, wherein said correction factor is generated from an auxiliary device that provides correction data concerning said dynamic position of said organ, and wherein when said correction data are combined with measurement data derived from said plurality of sensors to offset a response of said servo system so that said distal end moves substantially in unison with said organ.

18. The system of claim 11, wherein said auxiliary device is at least one of an X-ray device, an ultrasound device, and a radar device.

19. The system of claim 11, wherein said system controller includes a Virtual Tip control device to allow user control inputs.

20. The system of claim 11, wherein said first magnetic pole is extended and retracted by a hydraulic piston.

21. The system of claim 11, further comprising:

first controller to control said first coil; and

a second controller to control said second coil.

22. The system of claim 21, wherein said first controller receives feedback from a magnetic field sensor.

23. The system of claim 22, wherein said magnetic field sensor comprises a Hall effect sensor.

24. The system of claim 11, wherein said system controller coordinates flow of current through said first and second coils according to inputs from a Virtual tip.

25. The system of claim 24, wherein said Virtual Tip provides tactile feedback to an operator.

26. The system of claim 24, wherein said Virtual Tip provides tactile feedback to an operator according to a position error between an actual position of said distal end and a desired position of said distal end.

27. The system of claim 24, wherein said system controller causes said distal end to follow movements of said Virtual Tip.

28. The system of claim 24, further comprising:

an operator control to allow a user to control force or torque applied to the catheter distal end.

29. The system of claim 11, further comprising:

a controllable magnetic field source having a first cluster of poles and a second cluster of poles;

wherein at least one pole in said first cluster of poles is extendable;

a radar system configured to produce a radar image of organs of said body; and

one or more magnetic sensors to sense a magnetic field.

30. The system of claim 29, said distal end comprising one or more magnetic field sensors.

31. The system of claim 29, said distal end comprising one or more magnetic field sensors for providing sensor data to a system controller.

32. The system of claim 29, further comprising an operator interface unit.

33. The system of claim 29, wherein said first cluster of poles is coupled to said second cluster of poles by a magnetic material.