Method for continuous baroreflex sensitivity measurement
First Claim
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1. A method for calculating a continuous baroreflex sensitivity (BRS) value, comprising:
- detecting respiration cycles of a patient;
measuring heart rate of the patient over a first set of respiration cycles;
measuring a pressure metric of the patient over a second set of respiration cycles; and
calculating a BRS value based on the heart rate and pressure measurements, wherein the calculating the BRS value is based on heart rate and pressure measurements taken over different respiration cycles.
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Abstract
A medical device and method for determining baroreflex sensitivity (BRS) based on one or more respiration cycles. The BRS determination may be performed continuously based on measurements of heart rate, blood pressure, and respiration cycles.
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Citations
22 Claims
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1. A method for calculating a continuous baroreflex sensitivity (BRS) value, comprising:
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detecting respiration cycles of a patient; measuring heart rate of the patient over a first set of respiration cycles; measuring a pressure metric of the patient over a second set of respiration cycles; and calculating a BRS value based on the heart rate and pressure measurements, wherein the calculating the BRS value is based on heart rate and pressure measurements taken over different respiration cycles. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. An implantable medical device, comprising:
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one or more sensors for sensing patient heart rate, blood pressure, and respiration cycles; and a housing supporting a processor and adapted for implantation in a patient, the processor coupled to the one or more sensors, the processor for calculating continuous baroreflex sensitivity (BRS) for each detected respiration cycle based on the sensed heart rate, blood pressure and respiration cycles, wherein; the processor compares the BRS calculation against a zone of predetermined BRS thresholds, and the processor changes at least one zone threshold if the BRS calculation intermittently produces values outside the zone. - View Dependent Claims (9, 10, 11, 12)
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13. A computer-readable medium programmed with instructions for baroreflex sensitivity (BRS) measurement, the medium comprising instructions for causing a programmable processor to:
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detect respiration cycles of a patient; measure heart rate of the patient over a first set of respiration cycles; measure a pressure metric of the patient over a second set of respiration cycles; and calculate a BRS value based on the heart rate and pressure measurements, wherein the calculating the BRS value is based on heart rate and pressure measurements taken over different respiration cycles. - View Dependent Claims (14, 15, 16, 17)
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18. A computer-readable medium programmed with instructions for baroreflex sensitivity (BRS) measurement, the medium comprising instructions for causing a programmable processor to:
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determine patient heart rate, blood pressure, and respiration cycles from one or more sensors and calculate continuous baroreflex sensitivity (BRS) for each detected respiration cycle based on the sensed heart rate, blood pressure and respiration cycles; compare the BRS calculation against a zone of predetermined BRS thresholds, and change at least one zone threshold if the BRS calculation intermittently produces values outside the zone. - View Dependent Claims (19, 20, 21, 22)
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Specification