Method and system for detecting an occlusion in a tube

• US 7,875,004 B2
• Filed: 06/06/2007
• Issued: 01/25/2011
• Est. Priority Date: 06/08/2006
• Status: Active Grant

• Current Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Original Assignee: Medingo Ltd. (Roche Holding AG)
• Inventors: Iddan, Gavriel, Senesh, Gil, Yodfat, Ofer
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): LANDRY II, GERALD ERNEST
• Application Number:
  US11/810,854
• Publication Number:
  US 20080021395A1
• Time in Patent Office: 1,329 Days
• Field of Search: 604/131, 604/151, 604/890.1
• US Class Current: 604/151
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/16854 by monitoring line pressure

Abstract

Systems and methods for detecting an occlusion in a fluid delivery device are disclosed. The system includes a fluid delivery tube, an occlusion detection sensor configured to be coupled to the fluid delivery tube and further configured to detect occlusion within the fluid delivery tube. The fluid delivery tube includes an occlusion detection portion. The occlusion detection sensor is further configured to detect alteration of a shape of the occlusion detection portion when at least one condition occurs within the fluid delivery tube.

Claims

1. A fluid delivery device for delivering therapeutic fluid to a patient comprising:

a disposable part comprising a fluid delivery tube, said fluid delivery tube is substantially accommodated within a housing of said disposable part;

a reusable part comprising at least a first portion of an occlusion detection sensor configured to detect occlusion within a fluid passageway including at least said fluid delivery tube;

wherein;

said fluid delivery tube includes a protrusion extending from said fluid delivery tube, said protrusion is configured to change its orientation with respect to said fluid delivery tube when fluid pressure within said fluid delivery tube increases;

said occlusion detection sensor is configured to detect said change in the orientation of said protrusion; and

said occlusion detection sensor is operative upon coupling said reusable part and said disposable part.

2. The fluid delivery device according to claim 1, wherein:

the disposable part further comprises a reservoir coupled to said fluid delivery tube, from which therapeutic fluid is delivered to the patient via said fluid delivery tube; and

the reusable part further comprises at least a portion of a pump for pumping the therapeutic fluid from said reservoir.

3. The fluid delivery device according to claim 2, wherein said pump comprises a peristaltic pump which includes:

a stator plate located in the disposable part; and

a rotary wheel with rollers located in the reusable part,

wherein;

said stator plate and said rollers are configured to squeeze said fluid delivery tube upon coupling the reusable part to the disposable part; and

said peristaltic pump is configured to pump fluid from said reservoir via an inlet portion of said fluid delivery tube to an outlet portion of said fluid delivery tube upon squeezing said fluid delivery tube.

4. The fluid delivery device according to claim 1, wherein said occlusion detection sensor is configured to detect states of occlusion within said fluid passageway selected from a group consisting of:

no occlusion, partial occlusion, and total occlusion.

5. The fluid delivery device according to claim 1, further comprising an alarm configured to alert the patient when said occlusion detection sensor detects at least partial occlusion within said fluid passageway.

6. The fluid delivery device according to claim 1, wherein said occlusion detection sensor is further configured to detect normal delivery of therapeutic fluid to the patient based on a predetermined pressure value of the fluid within said fluid delivery tube, the predetermined pressure value being associated with said normal delivery.

7. The fluid delivery device according to claim 6, wherein said normal delivery is a pulsating delivery.

8. The fluid delivery device according to claim 1, wherein said occlusion detection sensor is further configured to detect leakage of therapeutic fluid from said fluid passageway based on a pressure of the fluid within said fluid delivery tube dropping below a threshold pressure value.

9. The fluid delivery device according to claim 1, wherein said occlusion detection sensor is further configured to detect presence of air within said fluid passageway.

10. The fluid delivery device according to claim 1, further comprising a control valve, wherein said control valve is configured to control delivery of the therapeutic fluid in said fluid delivery tube for variation of fluid pressure within said fluid delivery tube.

11. The fluid delivery device according to claim 10, wherein said control valve is configured such that when said control valve is closed, the fluid pressure within said fluid delivery tube increases, and when said control valve is open, the fluid pressure within said fluid delivery tube decreases.

12. The fluid delivery device according to claim 11, wherein during a normal operation of the fluid delivery device, the increase and decrease of said fluid pressure within said fluid delivery tube are periodic.

13. The fluid delivery device according to claim 1, wherein said reusable part further includes electronic components configured to at least one of collect data, process data and perform data analysis.

14. The fluid delivery device according to claim 1, wherein:

said disposable part further comprises at least a second portion of said occlusion detection sensor, and

said first portion of said occlusion detection sensor is operatively coupled to said second portion of said occlusion detection sensor upon coupling said reusable part and said disposable part.

15. A fluid delivery device for delivering therapeutic fluid to a patient comprising:

a disposable part comprising a fluid delivery tube, said fluid delivery tube is substantially accommodated within a housing of said disposable part; and

a reusable part comprising at least a first portion of an occlusion detection sensor configured to detect occlusion within a fluid passageway including at least said fluid delivery tube,

wherein;

said fluid delivery tube includes an occlusion detection portion,

said occlusion detection sensor comprises a light emitting source configured to emit light toward said occlusion detection portion, and a light collecting array configured to collect said light, wherein said occlusion detection portion is configured to reflect said light toward said light collecting array at a reflection angle,

said occlusion detection sensor is configured to detect occlusion within said fluid passageway based on a change in said reflection angle, said change corresponding to an alteration of a property of said occlusion detection portion when at least one condition occurs within said fluid delivery tube, and

said occlusion detection sensor is operative upon coupling said reusable part and said disposable part.

16. The fluid delivery device according to claim 15, wherein said at least one condition is a change in fluid pressure within said fluid delivery tube.

17. The fluid delivery device according to claim 16, wherein said occlusion detection portion is configured to expand when said fluid pressure within said fluid delivery tube increases.

18. The fluid delivery device according to claim 15, wherein:

the disposable part further comprises a reservoir coupled to said fluid delivery tube, from which therapeutic fluid is delivered to the patient via said fluid delivery tube, and

the reusable part further comprises at least a portion of a pump for pumping the therapeutic fluid from said reservoir.

19. The fluid delivery device according to claim 15, further comprising an alarm configured to alert the patient when said occlusion detection sensor detects at least partial occlusion within said fluid passageway.

20. The fluid delivery device according to claim 15, wherein said reusable part further includes electronic components configured to at least one of collect data, process data and perform data analysis.

21. The fluid delivery device according to claim 15, wherein said property of said occlusion detection portion is selected from a group consisting of:

shape, size, diameter, dimension, configuration, and orientation of said occlusion detection portion.

22. The fluid delivery device according to claim 15, wherein:

said disposable part further comprises at least a second portion of said occlusion detection sensor, and

said first portion of said occlusion detection sensor is operatively coupled to said second portion of said occlusion detection sensor upon coupling said reusable part and said disposable part.

23. A fluid delivery device for delivering therapeutic fluid to a patient comprising:

a disposable part comprising a fluid delivery tube, said fluid delivery tube being substantially accommodated within a housing of said disposable part; and

a reusable part comprising at least a first portion of an occlusion detection sensor configured to detect occlusion within a fluid passageway including at least said fluid delivery tube;

wherein;

said fluid delivery tube includes an occlusion detection portion;

said occlusion detection sensor comprises a light emitting source configured to emit light toward said occlusion detection portion, and a light collecting array configured to collect said light, wherein said occlusion detection portion is configured to block at least a portion of said light;

said occlusion detection sensor is configured to detect occlusion within said fluid passageway based on at least one of an amount of light collected by said light collecting array and an amount of light blocked by said occlusion detection portion, wherein said at least one of the amount of light collected by said light collecting array and the amount of light blocked by said occlusion detection portion corresponds to an alteration of a property of said occlusion detection portion when at least one condition occurs within said fluid delivery tube; and

said occlusion detection sensor is operative upon coupling said reusable part and said disposable part.

24. The fluid delivery device according to claim 23, wherein said at least one condition comprises a change in fluid pressure within said fluid delivery tube.

25. The fluid delivery device according to claim 24, wherein said occlusion detection portion is configured to expand when said fluid pressure within said fluid delivery tube increases.

26. The fluid delivery device according to claim 23, wherein:

the disposable part further comprises a reservoir coupled to said fluid delivery tube, from which therapeutic fluid is delivered to the patient via said fluid delivery tube, and

the reusable part further comprises at least a portion of a pump for pumping the therapeutic fluid from said reservoir.

27. The fluid delivery device according to claim 23, further comprising an alarm configured to alert the patient when said occlusion detection sensor detects at least partial occlusion within said fluid passageway.

28. The fluid delivery device according to claim 23, wherein said reusable part further includes electronic components configured to at least one of collect data, process data and perform data analysis.

29. The fluid delivery device according to claim 23, wherein said property of said occlusion detection portion is selected from a group consisting of:

shape, size, diameter, dimension, configuration, and orientation of said occlusion detection portion.

30. The fluid delivery device according to claim 23, wherein:

said disposable part further comprises at least a second portion of said occlusion detection sensor, and

said first portion of said occlusion detection sensor is operatively coupled to said second portion of said occlusion detection sensor upon coupling said reusable part and said disposable part.

31. A fluid delivery device for delivering therapeutic fluid to a patient comprising:

a disposable part comprising a fluid delivery tube, said fluid delivery tube is substantially accommodated within a housing of said disposable part;

a reusable part comprising at least a first portion of an occlusion detection sensor configured to detect occlusion within a fluid passageway including at least said fluid delivery tube;

wherein;

said fluid delivery tube includes an occlusion detection portion;

said occlusion detection sensor comprises a light emitting source configured to emit light and a light collecting array configured to collect said light, wherein said light emitting source and said light collecting array are configured to be located on the same side of said occlusion detection portion;

said occlusion detection sensor is configured to detect alteration of a property of said occlusion detection portion when at least one condition occurs within said fluid delivery tube; and

said occlusion detection sensor is operative upon coupling said reusable part and said disposable part.

32. The fluid delivery device according to claim 31, wherein said at least one condition comprises a change in fluid pressure within said fluid delivery tube.

33. The fluid delivery device according to claim 32, wherein said occlusion detection portion is configured to expand when said fluid pressure within said fluid delivery tube increases.

34. The fluid delivery device according to claim 31, wherein:

the disposable part further comprises a reservoir coupled to said fluid delivery tube, from which therapeutic fluid is delivered to the patient via said fluid delivery tube; and

the reusable part further comprises at least a portion of a pump for pumping the therapeutic fluid from said reservoir.

35. The fluid delivery device according to claim 34, wherein said pump comprises a peristaltic pump, said peristaltic pump including:

a stator plate located in the disposable part; and

a rotary wheel with rollers located in the reusable part,

wherein

said stator plate and said rollers are configured to squeeze said fluid delivery tube upon coupling the reusable part to the disposable part; and

said peristaltic pump is configured to pump fluid from said reservoir via an inlet portion of said fluid delivery tube to an outlet portion of said fluid delivery tube upon squeezing said fluid delivery tube.

36. The fluid delivery device according to claim 31, wherein said occlusion detection sensor is further configured to detect normal delivery of therapeutic fluid to the patient based on a predetermined pressure value of the fluid within said fluid delivery tube, the predetermined pressure value being associated with said normal delivery.

37. The fluid delivery device according to claim 31, wherein said normal delivery is a pulsating delivery.

38. The fluid delivery device according to claim 31, wherein said occlusion detection sensor is further configured to detect leakage of therapeutic fluid from said fluid passageway based on a pressure of the fluid within said fluid delivery tube dropping below a threshold pressure value.

39. The fluid delivery device according to claim 31, wherein said occlusion detection sensor is further configured to detect presence of air within said fluid passageway.

40. The fluid delivery device according to claim 31, further comprising a control valve, wherein said control valve is configured to control delivery of the therapeutic fluid in said fluid delivery tube for variation of fluid pressure within said fluid delivery tube.

41. The fluid delivery device according to claim 31, further comprising an alarm configured to alert the patient when said occlusion detection sensor detects at least partial occlusion within said fluid passageway.

42. The fluid delivery device according to claim 31, wherein said reusable part further includes electronic components configured to at least one of collect data, process data and perform data analysis.

43. The fluid delivery device according to claim 31, wherein said property of said occlusion detection portion is selected from a group consisting of:

shape, size, diameter, dimension, configuration, and orientation of said occlusion detection portion.

44. The fluid delivery device according to claim 31, wherein:

said disposable part further comprises at least a second portion of said occlusion detection sensor, and

said first portion of said occlusion detection sensor is operatively coupled to said second portion of said occlusion detection sensor upon coupling said reusable part and said disposable part.

45. A fluid delivery device for delivering therapeutic fluid to a patient comprising:

a disposable part comprising a fluid delivery tube, said fluid delivery tube is substantially accommodated within a housing of said disposable part;

a reusable part comprising at least a first portion of an occlusion detection sensor configured to detect occlusion within a fluid passageway including at least said fluid delivery tube;

wherein;

said fluid delivery tube includes an occlusion detection portion;

said occlusion detection sensor comprises a light emitting source configured to emit light and a light collecting array configured to collect said light, wherein said light emitting source and said light collecting array are configured to be located on opposite sides of said occlusion detection portion;

said occlusion detection sensor is configured to detect alteration of a property of said occlusion detection portion when at least one condition occurs within said fluid delivery tube; and

said occlusion detection sensor is operative upon coupling said reusable part and said disposable part.

46. The fluid delivery device according to claim 45, wherein said at least one condition is a change in fluid pressure within said fluid delivery tube.

47. The fluid delivery device according to claim 46, wherein said occlusion detection portion is configured to expand when said fluid pressure within said fluid delivery tube increases.

48. The fluid delivery device according to claim 45, wherein:

the disposable part further comprises a reservoir coupled to said fluid delivery tube, from which therapeutic fluid is delivered to the patient via said fluid delivery tube; and

the reusable part further comprises at least a portion of a pump for pumping the therapeutic fluid from said reservoir.

49. The fluid delivery device according to claim 48, wherein said pump comprises a peristaltic pump, said peristaltic pump including:

a stator plate located in the disposable part; and

a rotary wheel with rollers located in the reusable part,

wherein;

said stator plate and said rollers are configured to squeeze said fluid delivery tube upon coupling the reusable part to the disposable part, and

said peristaltic pump is configured to pump fluid from said reservoir via an inlet portion of said fluid delivery tube to an outlet portion of said fluid delivery tube upon squeezing said fluid delivery tube.

50. The fluid delivery device according to claim 45, wherein said occlusion detection sensor is further configured to detect normal delivery of therapeutic fluid to the patient based on a predetermined pressure value of the fluid within said fluid delivery tube, the predetermined pressure value being associated with said normal delivery.

51. The fluid delivery device according to claim 45, wherein said normal delivery is a pulsating delivery.

52. The fluid delivery device according to claim 45, wherein said occlusion detection sensor is further configured to detect leakage of therapeutic fluid from said fluid passageway based on a pressure of the fluid within said fluid delivery tube dropping below a threshold pressure value.

53. The fluid delivery device according to claim 45, wherein said occlusion detection sensor is further configured to detect presence of air within said fluid passageway.

54. The fluid delivery device according to claim 45, further comprising a control valve, wherein said control valve is configured to control delivery of the therapeutic fluid in said fluid delivery tube for variation of fluid pressure within said fluid delivery tube.

55. The fluid delivery device according to claim 45, further comprising an alarm configured to alert the patient when said occlusion detection sensor detects at least partial occlusion within said fluid passageway.

56. The fluid delivery device according to claim 45, wherein said reusable part further includes electronic components configured to at least one of collect data, process data and perform data analysis.

57. The fluid delivery device according to claim 45, wherein said property of said occlusion detection portion is selected from a group consisting of:

shape, size, diameter, dimension, configuration, and orientation of said occlusion detection portion.

58. The fluid delivery device according to claim 45, wherein:

said disposable part further comprises at least a second portion of said occlusion detection sensor, and

said first portion of said occlusion detection sensor is operatively coupled to said second portion of said occlusion detection sensor upon coupling said reusable part and said disposable part.

59. A fluid delivery device for delivering therapeutic fluid to a patient comprising:

a disposable part comprising a fluid delivery tube, said fluid delivery tube is substantially accommodated within a housing of said disposable part; and

a reusable part comprising at least a first portion of an occlusion detection sensor configured to detect occlusion within a fluid passageway including at least said fluid delivery tube;

wherein;

said fluid delivery tube includes an occlusion detection portion;

said occlusion detection sensor comprises movable capacitance plates;

said occlusion detection portion is configured to change a distance between said movable capacitance plates upon change of fluid pressure within said fluid delivery tube;

said occlusion detection sensor is configured to detect occlusion within said fluid passageway based on a change in said distance between said movable capacitance plates, said change in said distance corresponding to an alteration of a property of said occlusion detection portion when said change in fluid pressure within said fluid delivery tube occurs; and

said occlusion detection sensor is operative upon coupling said reusable part and said disposable part.

60. The fluid delivery device according to claim 59, wherein said occlusion detection portion is configured to expand when said fluid pressure within said fluid delivery tube increases.

61. The fluid delivery device according to claim 59, wherein:

the disposable part further comprises a reservoir coupled to said fluid delivery tube, from which therapeutic fluid is delivered to the patient via said fluid delivery tube; and

the reusable part further comprises at least a portion of a pump for pumping the therapeutic fluid from said reservoir.

62. The fluid delivery device according to claim 60, wherein said pump comprises a peristaltic pump, said peristaltic pump including:

a stator plate located in the disposable part; and

a rotary wheel with rollers located in the reusable part,

wherein

said stator plate and said rollers are configured to squeeze said fluid delivery tube upon coupling the reusable part to the disposable part, and

said peristaltic pump is configured to pump fluid from said reservoir via an inlet portion of said fluid delivery tube to an outlet portion of said fluid delivery tube upon squeezing said fluid delivery tube.

63. The fluid delivery device according to claim 59, wherein said occlusion detection sensor is further configured to detect normal delivery of therapeutic fluid to the patient based on a predetermined pressure value of the fluid within said fluid delivery tube, the predetermined pressure value being associated with said normal delivery.

64. The fluid delivery device according to claim 59, wherein said normal delivery is a pulsating delivery.

65. The fluid delivery device according to claim 59, wherein said occlusion detection sensor is further configured to detect leakage of therapeutic fluid from said fluid passageway based on a pressure of the fluid within said fluid delivery tube dropping below a threshold pressure value.

66. The fluid delivery device according to claim 59, further comprising a control valve, wherein said control valve is configured to control delivery of the therapeutic fluid in said fluid delivery tube for variation of fluid pressure within said fluid delivery tube.

67. The fluid delivery device according to claim 59, further comprising an alarm device configured to alert the patient when said occlusion detection sensor detects at least partial occlusion within said fluid passageway.

68. The fluid delivery device according to claim 59, wherein said reusable part further includes electronic components configured to at least one of collect data, process data and perform data analysis.

69. The fluid delivery device according to claim 59, wherein said property of said occlusion detection portion is selected from a group consisting of:

shape, size, diameter, dimension, configuration, orientation and other property of said occlusion detection portion.

70. The fluid delivery device according to claim 59, wherein said occlusion detection sensor is configured to be coupled to said occlusion detection portion of said fluid delivery tube.

71. The fluid delivery device according to claim 59, wherein:

said disposable part further comprises at least a second portion of said occlusion detection sensor, and

said first portion of said occlusion detection sensor is operatively coupled to said second portion of said occlusion detection sensor upon coupling said reusable part and said disposable part.