Active suture for the delivery of therapeutic fluids

• US 7,875,055 B2
• Filed: 08/02/2004
• Issued: 01/25/2011
• Est. Priority Date: 12/04/2003
• Status: Active Grant

• Current Assignee: Ethicon Incorporated (Johnson & Johnson)
• Original Assignee: Ethicon Incorporated (Johnson & Johnson)
• Inventors: Cichocki, Frank R. Jr.
• Primary Examiner(s): Jackson; Gary
• Assistant Examiner(s): NGUYEN, TUAN VAN
• Application Number:
  US10/909,717
• Publication Number:
  US 20050125035A1
• Time in Patent Office: 2,367 Days
• Field of Search: 606222-232, 606/139, 604/93.01, 604/164.08, 604/164.09, 604/523, 604/524, 604/525, 604/526, 604/527
• US Class Current: 606/228
• CPC Class Codes: A61B 17/0469 Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 2017/0404 Buttons
• CPC Class Codes: A61B 2017/0458 Longitudinal through hole, e.g. suture blocked by a distal suture knot
• CPC Class Codes: A61B 2017/0464 for soft tissue
• CPC Class Codes: A61B 2017/0475 using sutures having a slip knot
• CPC Class Codes: A61B 2017/06185 hollow or tubular hollow suture needles A61B2017/061
• CPC Class Codes: A61M 37/00 Other apparatus for introducing media into the body for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30; Percutany, i.e. introducing medicines into the body by diffusion through the skin salt baths A61H33/04

Abstract

An active suture that can be used for the delivery of therapeutic fluids to the tissue surrounding a wound is disclosed. The active suture may include a connector designed to join a fluid source, such as a syringe, conventional IV delivery system, or infusion pump to an internal passageway that is embedded within a braided suture. The internal passageway may be comprised of a fine polymeric tube and is capable of conducting and emitting a fluid into at least a portion of the braided suture and surrounding tissue. The invention enables delivery of an efficacious volume of drug bearing solution on the order of milliliters per day, provides a high level of fluid delivery rate control enabling the physician to start or stop drug administration at his/her discretion, and offers a means of providing more than one type of medication that may be selected post-surgically in accord with unexpected patient symptoms that may arise.

Claims

1. An active suture/needle assembly for delivering a fluid supplied under pressure, comprising

an active suture comprising

a braided suture having proximal and distal ends and an outer diameter, said braided suture having a plurality of interstices along at least a portion of its length;

and

a tube having proximal and distal ends and internally coaxial with at least a portion of the braided suture, said tube having one or more openings therein along at least a portion of its length, said tube having an internal passageway ranging from about 75 μ

m to 135 μ

m in diameter for conducting the fluid supplied under pressure via the one or more openings to the plurality of interstices of said braided suture;

a surgical needle attached to the distal end of the braided suture; and

a connector attached to the proximal end of the tube.

2. An active suture/needle/fluid source assembly for delivering a fluid, said active suture/needle/fluid source assembly comprising

an active suture comprising

a braided suture having proximal and distal ends and an outer diameter, said braided suture having a plurality of interstices along at least a portion of its length;

and

a tube having proximal and distal ends and internally coaxial with at least a portion of the braided suture, said tube having an internal passageway and one or more openings along at least a portion of its length for conducting the fluid to the plurality of interstices of said braided suture;

a surgical needle attached to the distal end of the braided suture;

a connector attached to the proximal end of the tube; and

an external fluid source for supplying fluid under pressure, said external fluid source in fluid communication with said connector, wherein the fluid is supplied to said assembly at a pressure exceeding that which can evolve within said assembly due to capillary or diffusional phenomena.

3. The assembly of claim 2, wherein said distal end of said tube includes an opening and said distal end of said tube is disposed between said proximal and distal ends of said braided suture.

4. The assembly of claim 3, wherein said tube includes a plurality of openings.