Block copolymers of acrylates and methacrylates with fluoroalkenes
First Claim
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1. An implantable device which is a drug-eluting stent, comprising a coating that comprises a bioactive agent and a block copolymer, the block copolymer comprising a fluorinated block and at least one non-fluorinated block, wherein the fluorinated block is a poly(fluoroalkene) having repeating units of the following structure:
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Abstract
A block copolymer comprising a fluorinated block and a non-fluorinated block and method of making the block copolymer are provided. Also provided herein are a coating on an implantable device comprising the block copolymer and method of using the implantable device.
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16 Claims
- 1. An implantable device which is a drug-eluting stent, comprising a coating that comprises a bioactive agent and a block copolymer, the block copolymer comprising a fluorinated block and at least one non-fluorinated block, wherein the fluorinated block is a poly(fluoroalkene) having repeating units of the following structure:
- 15. A method of treating restenosis or vulnerable plaque, comprising implanting in a human being in need thereof an implantable device comprising a coating which comprises a block copolymer, the block copolymer comprising a fluorinated block and at least one non-fluorinated block, wherein the fluorinated block is a poly(fluoroalkene) having repeating units of the following structure:
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