Fiber based embolism protection device

• US 7,879,067 B2
• Filed: 10/02/2007
• Issued: 02/01/2011
• Est. Priority Date: 07/22/2003
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Lumen Biomedical, Inc.
• Inventors: Hinnenkamp, Thomas F., Pokorney, Jim, Galdonik, Jason A., Ogle, Matthew F.
• Primary Examiner(s): Nguyen; Anhtuan T
• Assistant Examiner(s): Houston; Elizabeth
• Application Number:
  US11/865,891
• Publication Number:
  US 20080109088A1
• Time in Patent Office: 1,218 Days
• Field of Search: 606/200, 606/113, 606/114, 606/108, 606/127, 606/159, 606191-199, 604104-107
• US Class Current: 606/200
• CPC Class Codes: A61F 2/01 Filters implantable into blood vessels
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61M 2025/09175 having specific characteristics at the distal tip
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: B33Y 80/00 Products made by additive manufacturing

Abstract

Improved embolism protection devices comprises fibers that can have one configuration for delivery of the device and a second configuration in which the device is deployed for filtering of flow within a vessel. In some embodiments, the fibers can be connected to a fiber support, which is connected to an actuating element. The actuating element controls the transition from the delivery configuration to the deployed configuration. The embolism protection device can comprise a guidewire. The fibers can be attached at one end to a fiber support structure and at another end to the guidewire. A hypotube can be attached to the proximal end of the fibers while the guidewire is attached at the distal end of the fibers with the guidewire extending within a central channel of the hypotube. The hypotube can be used to guide the delivery of treatment structures, such as a balloon and/or a stent.

Claims

1. An embolism protection device comprising

a. at least about 50 biocompatible surface capillary polymer fibers, wherein the surface capillary fibers comprises surface capillaries that run substantially along the length of the fibers;

b. a wire;

c. a hypotube having a distal end and a proximal end; and

d. a distal coil,

wherein the fibers are distally bound and proximally bound with relative movement of the wire and the hypotube changing the distance between the distally bound end and the proximally bound end of the fibers,

wherein the wire extends through a lumen of the hypotube,

wherein the distal coil covers the wire at its distal end,

wherein the fibers have a first configuration in which the fibers are confined within a narrow profile configuration and a second configuration in which ends of the fibers are constrained while the remaining portion of the fibers are unconstrained with respect to the narrow profile,

wherein all the fibers are substantially aligned in the first configuration and the second configuration has the unconstrained portion of the fibers projecting outward to form a porous filtration matrix that conforms to a geometry of a surrounding vessel wherein the fibers in the second configuration define a plurality of pores that are sized to trap emboli within the matrix with sizes from about 50 microns to about 200 microns, and

wherein relative movement of the wire and the hypotube transitions the fibers from the narrow profile configuration to the second configuration.

2. The embolism protection device of claim 1 further comprising a coil attached to the distal end of the hypotube.

3. The embolism protection device of claim 1 wherein the surface capillary fibers comprise polyester.

4. The embolism protection device of claim 1 wherein the fibers are heat bonded to connect the fibers to the wire at the distal end.

5. The embolism protection device of claim 1 further comprising a band that encircles the fibers near the fiber ends to secure the fibers.

6. The embolism protection device of claim 1 wherein the fibers have a size from about 0.5 denier to about 25 denier.

7. The embolism protection device of claim 1 wherein the fibers have a diameter from about 150 microns to about 1 millimeter.

8. The embolism protection device of claim 1 wherein the fibers have a specific capillary volume of at least about 0.5 cc/g.

9. The embolism protection device of claim 1 wherein the fiber has a specific surface capillary volume of at least about 500 cm²/g.

10. The embolism protection device of claim 1 wherein the fiber has a length from about 0.5 mm to about 25 mm.

11. The embolism protection device of claim 1 wherein the hypotube has an outer diameter of about 0.014 inches.

12. The embolism protection device of claim 1 wherein the fibers are twisted in a substantially parallel configuration.