Implant delivery system and methods thereof for treating ocular disorders

• US 7,879,079 B2
• Filed: 06/19/2006
• Issued: 02/01/2011
• Est. Priority Date: 08/28/2001
• Status: Active Grant

• Current Assignee: Glaukos Corporation
• Original Assignee: Glaukos Corporation
• Inventors: Niksch, Barbara A., Smedley, Gregory T., Haffner, David S., Tu, Hosheng, Gharib, Morteza
• Primary Examiner(s): Robert; Eduardo C
• Assistant Examiner(s): Mendoza; Michael G
• Application Number:
  US11/455,391
• Publication Number:
  US 20070010827A1
• Time in Patent Office: 1,688 Days
• Field of Search: 606/108, 623/1.11
• US Class Current: 623/1.11
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2002/9505 having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
• CPC Class Codes: A61F 2002/9511 the retaining means being filaments or wires
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: A61M 27/002 Implant devices for drainage of body fluids from one part of the body to another intraocular A61F9/00781; middle ear A61F11/202

Abstract

Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.

Claims

1. A method of implanting a stent in an eye, comprising:

advancing a piercing member along an axis to create an opening at trabecular meshwork of the eye;

delivering the stent by moving the stent along a side of the piercing member and through the opening such that a distal section of the stent resides in Schlemm'"'"'s canal, with a surface of the distal section abutting a surface of Schlemm'"'"'s canal and extending generally perpendicular to said axis laterally within Schlemm'"'"'s canal to stabilize the implanted stent.

2. The method of claim 1, wherein a proximal-most end of the stent is disposed in an anterior chamber of the eye.

3. The method of claim 1, wherein the piercing member extends through a lumen in the stent, said delivery comprising using the piercing member to guide the stent into the opening.

4. A method of implanting a stent in an eye, comprising:

advancing a piercing member along an axis to create an opening at the trabecular meshwork of the eye;

delivering the stent by moving the stent along a side of the piercing member and through the opening such that a distal section of the stent resides in Schlemm'"'"'s canal, and a long axis of the stent extends from a proximal section of the stent to the distal section, with a surface of the distal section abutting a surface of Schlemm'"'"'s canal and extending generally perpendicular to said axis, along which the piercing member is advanced, laterally within Schlemm'"'"'s canal to stabilize the implanted stent, said surface of the distal section extending laterally away from said long axis.

5. The method of claim 4, wherein said proximal section is positioned in an anterior chamber of the eye.

6. A method of positioning an implant in an eye such that the implant conducts fluid from an anterior chamber of the eye to Schlemm'"'"'s canal of the eye, said method comprising:

introducing the implant into the anterior chamber of the eye;

using a piercing member to form an opening in eye tissue by advancing the piercing member along an axis;

moving the implant into the opening by advancing the implant along a length of the piercing member;

positioning the implant such that a distal section is in Schlemm'"'"'s canal and a proximal section is in the anterior chamber with a long axis of the implant extending between the proximal and distal sections of the implant, said positioning comprising abutting a ledge of the distal section, which is generally perpendicular to the long axis of the implant, against a surface of Schlemm'"'"'s canal, such that the ledge extends generally perpendicular to said axis, along which the piercing member is advanced, laterally within Schlemm'"'"'s canal to stabilize the implanted implant.

7. The method of claim 6, wherein said positioning additionally comprises abutting a surface of the proximal section against a surface of the trabecular meshwork.

8. The method of claim 6, wherein said ledge extends in a direction that is substantially parallel to said surface of Schlemm'"'"'s canal.