Hepatic electrical stimulation
First Claim
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1. A method of electrical stimulation of an afferent vagal nerve of a subject having a liver parenchyma, said method comprising:
- positioning one or more stimulatory electrodes in or on the liver parenchyma of the subject; and
providing electrical stimulation to the liver parenchyma of the subject;
wherein electrical stimulation to the liver parenchyma stimulates the afferent vagal nerve.
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Abstract
A method of providing electrical stimulation to a liver of a subject includes providing one or more stimulatory electrodes to the liver of the subject and providing electrical stimulation to the liver of the subject. The method further relates to methods of reducing risk factors of metabolic syndrome, treating diabetes, treating a subject having eating disorders and reducing glucose levels of a subject.
48 Citations
15 Claims
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1. A method of electrical stimulation of an afferent vagal nerve of a subject having a liver parenchyma, said method comprising:
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positioning one or more stimulatory electrodes in or on the liver parenchyma of the subject; and providing electrical stimulation to the liver parenchyma of the subject;
wherein electrical stimulation to the liver parenchyma stimulates the afferent vagal nerve. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method of placing a vagal nerve stimulatory device on a surface of the liver parenchyma or into the liver parenchyma of a subject, wherein the placement occurs from the exterior of the subject, said method comprising:
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inserting an end of a needle with an interior bore from the exterior of the subject to the surface of or into the liver parenchyma of the subject; inserting the device through the interior bore of the needle until the device engages at least the surface of the liver parenchyma; removing the needle, wherein the device is placed on the surface of or into the liver parenchyma of the subject;
wherein the device is an electrode.
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Specification