Endoluminal device with extracellular matrix material and methods

• US 7,887,576 B2
• Filed: 05/19/2009
• Issued: 02/15/2011
• Est. Priority Date: 08/20/2002
• Status: Expired due to Term

• Current Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Original Assignee: Cook Biotech Incorporated (Cook Group Incorporated), Cook Incorporated (Cook Group Incorporated), MED Institute, Inc. (Cook Group Incorporated)
• Inventors: Sun, Jichao, Bahler, Clinton D., Leewood, Alan R., Ninan, Lal, Mead, Jason A., DeBruyne, Michael P., Osborne, Thomas A., Fearnot, Neal E.
• Primary Examiner(s): GHERBI, SUZETTE JAIME J
• Application Number:
  US12/468,383
• Publication Number:
  US 20090248144A1
• Time in Patent Office: 637 Days
• Field of Search: 623 115- 148, 424/423
• US Class Current: 623/1.13
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2002/8486 provided on at least one of the ends
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2250/0065 telescopic

Abstract

An endoluminal device comprises a stent and a tubular graft supported by the stent. The graft has a proximal and a distal opening and comprises a synthetic material and a bioremodelable material. The bioremodelable material is disposed on an exterior surface in at least one band adjacent at least one of the proximal and distal openings.

Claims

1. An endoluminal device comprising:

a stent;

a first tubular graft supported by the stent, the first tubular graft comprising a proximal opening, a distal opening, and a synthetic material; and

a tubular bioremodelable material having two open ends, wherein the tubular bioremodelable material extends the length of the first tubular graft beyond at least one of the proximal and distal openings of the first tubular graft.

2. The endoluminal device of claim 1, wherein the tubular bioremodelable material comprises one of an extracellular matrix material and a synthetic matrix material.

3. The endoluminal device of claim 2, wherein the extracellular matrix material comprises purified small intestine submucosa.

4. The endoluminal device of claim 1, wherein one of the open ends of the tubular bioremodelable material is affixed to the one of the proximal or distal openings of the first tubular graft.

5. The endoluminal device of claim 4, wherein the tubular bioremodelable material is affixed by suturing, stitching, gluing, or stapling.

6. The endoluminal device of claim 4, further comprising a second tubular graft supported by another stent and having an open end, the second tubular graft comprising a synthetic material, wherein the open end of the second tubular graft is affixed to the other open end of the tubular bioremodelable graft material so that the tubular bioremodelable material connects the first tubular graft with the second tubular graft.

7. The endoluminal device of claim 6, wherein the second tubular graft is affixed by suturing, stitching, gluing, or stapling.

8. The endoluminal device of claim 2, wherein the stent is at least partially coated with the extracellular matrix material.

9. An endoluminal device comprising:

a first prosthetic module having an opening at one end;

a second prosthetic module having an opening at one end; and

a tubular bioremodelable module having two open ends, wherein the tubular bioremodelable material connects the opening of the first prosthetic module with the opening of the second prosthetic module.

10. The endoluminal device of claim 9, wherein the tubular bioremodelable material comprises one of an extracellular matrix material and a synthetic matrix material.

11. The endoluminal device of claim 9, wherein the extracellular matrix material comprises purified small intestine submucosa.

12. An endoluminal device comprising:

a stent;

a tubular graft supported by the stent, the tubular graft comprising

a proximal opening,

a distal opening,

at least one other opening disposed in the tubular graft between the proximal and the distal openings, and

a synthetic material; and

a bioremodelable material associated with an exterior surface of the tubular graft in at least one band adjacent the other opening disposed in the tubular graft.

13. The endoluminal device of claim 12, wherein the bioremodelable material comprises one of an extracellular matrix material and a synthetic matrix material.

14. The endoluminal device of claim 12, wherein the extracellular matrix material comprises purified small intestine submucosa.

15. The endoluminal device of claim 13, wherein the extracellular matrix material comprises at least one filament of purified small intestine submucosa.

16. The endoluminal device of claim 15, wherein the at least one filament of purified small intestine submucosa is associated with the graft by one of weaving, knitting, and sewing.

17. The endoluminal device of claim 13, wherein the extracellular matrix material comprises a purified small intestine submucosa particulate associated with the graft by a process selected from a group consisting of impregnating in the synthetic material and coating on the synthetic material.

18. The endovascular device of claim 13, wherein the extracellular matrix material comprises at least one sheet of purified small intestine submucosa that is affixed to the exterior surface of the tubular graft.

19. The endovascular device of claim 18, wherein the at least one sheet of purified small intestine submucosa is associated with the graft by affixing with one of adhesive, staples, and sutures.

20. The endovascular device of claim 13, wherein the extracellular matrix material is impregnated into the synthetic material with the assistance of a partial vacuum.