Controllable valve and inhalation device

• US 7,891,358 B2
• Filed: 06/29/2006
• Issued: 02/22/2011
• Est. Priority Date: 07/06/2005
• Status: Expired due to Fees

• Current Assignee: Vectura GmbH (Vectura Group Ltd.)
• Original Assignee: Activaero GmbH (Philip Morris Limited)
• Inventors: Kolb, Tobias, Roeder, Sascha
• Primary Examiner(s): Douglas; Steven O
• Application Number:
  US11/427,567
• Publication Number:
  US 20070006883A1
• Time in Patent Office: 1,699 Days
• Field of Search: 128/205.24, 137/175, 138/45, 138/46
• US Class Current: 128/205.24
• CPC Class Codes: A61M 11/00 Sprayers or atomisers specially adapted for therapeutic purposes in general B05B; aerosol containers B65D83/14
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 15/0016 located downstream of the dispenser, i.e. traversed by the product
• CPC Class Codes: A61M 15/002 with air flow regulating means
• CPC Class Codes: A61M 15/0091 mechanically breath-triggered
• CPC Class Codes: A61M 16/20 Valves specially adapted to medical respiratory devices
• CPC Class Codes: A61M 16/201 Controlled valves
• CPC Class Codes: A61M 2205/3379 Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 39/22 Valves or arrangement of valves A61M39/02, A61M39/0247, A61M39/16 take precedence; regulating valves in infusion systems A61M5/16881; in devices worn by the patient for the reception of urine, faeces, catamenial or other discharge, or in colostomy devices A61F5/4405

Abstract

The present invention relates to an improved controllable valve, in particular for an inhalation device, which, e.g., comprises a container for a predetermined aerosol volume, a means for disbursing an aerosol from an aerosol dispenser into the container and a control means that keeps the inhalation flow essentially constant during the entire inhalation. The control means comprises an either continuously or gradually controllable valve so as to limit the flow rate.

Claims

1. An inhalation device comprising a control means having a flow channel therethrough, the control means keeping the inhalation flow essentially constant during an entire aerosol inhalation by reducing a cross-section of the flow channel, wherein the control means comprises a controllable valve including

a housing,

a closure element,

a membrane forming a wall of the flow channel, the membrane arching into the flow channel, thereby reducing the cross-section of the flow channel, in response to a lowered pressure within the housing,

a pressure plate,

a set piston and

an adjusting screw secured to the set piston and axially adjustable relative to the housing in order to adjust the flow rate through the controllable valve.

2. The inhalation device according to claim 1, wherein the controllable valve is a continuously variable flow limiter.

3. The inhalation device according to claim 1, wherein the controllable valve is a flow limiter that is adjustable in several steps.

4. The inhalation device according to claim 1, wherein the housing is essentially tubular and comprises a plurality of radially arranged webs, one web being longer than the others.

5. The inhalation device according to claim 4, wherein on the one side of the webs the housing is designed so as to adjustably receive the set piston and on the opposite side so as to receive the membrane, the pressure plate and the closure element.

6. The inhalation device according to claim 4, wherein the membrane is forced against the webs of the housing by the pressure plate and the closure element so that a space is formed between the membrane and the set piston.

7. The inhalation device according to claim 1, wherein the membrane is disk-shaped and provided with a collar at its edge.

8. The inhalation device according to claim 4, wherein the set piston comprises a plurality of radially arranged recesses corresponding to the webs of the housing at its front end facing the membrane, one recess being longer than the others.

9. The inhalation device according to claim 1, wherein the set piston is sealingly received in the housing.

10. The inhalation device according to claim 1, wherein the adjusting screw is axially fixable to the set piston and the set piston is axially adjustable with respect to the housing via the adjusting screw.

11. The inhalation device according to claim 8, wherein the adjusting screw comprises at least one opening in an area between two adjoining recesses of the plurality of radially arranged recesses.

12. The inhalation device according to claim 11 further comprising at least one pair of adjoining recesses and between each pair of which two openings are provided which are situated on a common circumferential line and are spaced apart from each other by approx. 45°

.

13. The inhalation device according to claim 4, wherein at least portions of the housing, the membrane, the pressure plate, the closure element and the set piston are provided with a central flow channel.

14. The inhalation device according to claim 1, wherein the adjusting screw is screwed into the housing.

15. The inhalation device according to claim 1, wherein the adjusting screw is connected to the housing via a sliding block guide so as to axially guide the set piston.

16. A controllable valve having a flow channel therethrough for use in an inhalation device, comprising:

a housing,

a membrane,

a pressure plate,

a closure element, a set piston and

an adjusting screw for adjusting a flow rate through the controllable valve,

wherein the housing is essentially tubular and comprises a plurality of radially arranged webs, one web being longer than the others, wherein on one side of the webs the housing is designed so as to adjustably receive the set piston in order to adjust the flow rate through the controllable valve and on the opposite side so as to receive the membrane, the optional pressure plate and the closure element, and

wherein the membrane forms part of the flow channel and arches into the flow channel in response to a lowered pressure within the housing.

17. The controllable valve according to claim 16, wherein the membrane is forced against the webs of the housing by means of the pressure plate of the closure element so that a space is formed between the membrane and the set piston.

18. The controllable valve according to claim 16, wherein the membrane is disk-shaped and is provided with a collar at its edge.

19. The controllable valve according to claim 16, wherein at its front end facing the membrane the set piston comprises a plurality of radially arranged recesses corresponding to the webs of the housing, one recess being longer than the others.

20. The controllable valve according to claim 16, wherein the set piston is sealingly received within the housing.

21. The controllable valve according to claim 16, wherein the adjusting screw is axially fixable to the set piston and the set piston is axially adjustable with respect to the housing by means of the adjusting screw.

22. The controllable valve according to claim 16, wherein in an area between adjoining recesses the adjusting screw is provided with at least one opening.

23. The controllable valve according to claim 22, wherein each pair of adjoining recesses is provided with two openings which are situated on a common circumferential line and are spaced apart from each other by approx. 45°

.

24. The controllable valve according to claim 16, wherein at least portions of the housing, the membrane, the pressure plate, the closure and the set piston are provided with a central flow channel.

25. A controllable valve according to claim 16, wherein the adjusting screw is screwed into the housing.

26. The controllable valve according to claim 16, wherein the adjusting screw is connected to the housing by means of a sliding block guide so as to axially guide the set piston.

27. The controllable valve according to claim 16 in the form of a continuously variable flow limiter.

28. The controllable valve according to claim 16 in the form of a flow limiter that is adjustable in several steps.

29. The controllable valve according to claim 16, wherein the valve is used in an inhalation device to keep the inhalation flow rate essentially constant during an entire aerosol inhalation cycle.