×

Electrochemical biosensors, applications and methods of making biosensors

  • US 7,892,414 B1
  • Filed: 11/15/2005
  • Issued: 02/22/2011
  • Est. Priority Date: 11/19/2004
  • Status: Expired due to Fees
First Claim
Patent Images

1. A biosensor comprising:

  • a) an electrode;

    b) a non-conductive polymer deposited on the electrode to form a matrix material having a plurality of pores therethrough;

    c) a capture biomolecule immobilized on the matrix material capable of binding a target analyte in a sample to be analyzed;

    wherein the binding of the target analyte to the capture biomolecule effectively blocks a sufficient number of pores in the matrix material to produce a measurable decrease in the rate of a redox reaction occurring at the electrode;

    d) a current source, wherein the current source provides a flow of electrons to drive a redox reaction at the electrode between the electrode and a redox species in contact with the electrode; and

    e) a detector element coupled to the electrode to detect the measureable decrease a change in the rate of a redox reaction occurring at the electrode due to the number of pores in the matrix material blocked by the binding of the target analyte.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×