×

Mesoscale polynucleotide amplification devices

  • US 7,892,819 B2
  • Filed: 08/11/2003
  • Issued: 02/22/2011
  • Est. Priority Date: 05/01/1992
  • Status: Expired due to Fees
First Claim
Patent Images

1. A device for amplifying a polynucleotide in a sample by conducting a polynucleotide amplification reaction, the device comprising a solid substrate microfabricated to define:

  • a sample inlet port;

    a mesoscale flow system comprising;

    a sample flow channel extending from said inlet port; and

    a polynucleotide amplification region of the device, in fluid communication with said flow channel, said region having at least one cross-sectional dimension of width or depth of about 0.1 to 1000 microns, at least said polynucleotide amplification region being permanently sealed with a cover; and

    an appliance for use in combination with said substrate, said appliance including a nesting site for receiving said substrate and a conduit in fluid communication with the inlet port of said substrate.

View all claims
  • 0 Assignments
Timeline View
Assignment View
    ×
    ×