Apparatus and method for assessing cardiac therapy
First Claim
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1. A method of assessing effectiveness of cardiac therapy, comprising:
- delivering cardiac resynchronization pacing pulses to left and right ventricles of a patient'"'"'s heart to control synchronization of contractions of the left and right ventricles;
collecting an evoked response from an intracardiac electrogram (IEGM) of the left and right ventricles in response to the delivered pacing pulses;
extracting one or more parameters from the collected evoked response;
collecting data associated with activity of the patient; and
cross correlating the one or more parameters extracted from the evoked response and the collected activity data to generate an indication of effectiveness of the cardiac resynchronization pulses delivered to the left and right ventricles.
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Abstract
A patient'"'"'s response to therapy such as CRT is assessed by cross correlation of a patient'"'"'s evoked response and physical activity surrogates. Based on the cross correlation, a determination may be made as to whether or how much the therapy is helping the patient'"'"'s physical activity. For example, the degree of cross correlation index between IEGM parameters and activity threshold parameters may be used to assess whether the patient'"'"'s heart condition improves the patient'"'"'s physical activity. The therapy may then be modified as necessary in the event the patient is not sufficiently responding to the therapy.
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Citations
20 Claims
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1. A method of assessing effectiveness of cardiac therapy, comprising:
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delivering cardiac resynchronization pacing pulses to left and right ventricles of a patient'"'"'s heart to control synchronization of contractions of the left and right ventricles; collecting an evoked response from an intracardiac electrogram (IEGM) of the left and right ventricles in response to the delivered pacing pulses; extracting one or more parameters from the collected evoked response; collecting data associated with activity of the patient; and cross correlating the one or more parameters extracted from the evoked response and the collected activity data to generate an indication of effectiveness of the cardiac resynchronization pulses delivered to the left and right ventricles. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. An apparatus adapted to assess effectiveness of cardiac therapy, comprising:
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a pulse generator adapted to deliver cardiac resynchronization pacing pulses to left and right ventricles of a patient'"'"'s heart to control synchronization of contractions of the left and right ventricles; an evoked response circuit adapted to obtain data associated with an evoked response from an intracardiac electrogram of a patient in response to the delivered cardiac resynchronization pacing pulses and to extract one or more parameters from the evoked response data; an activity level circuit adapted to obtain data associated with activity of the patient; and a cross correlator adapted to cross correlate the one or more extracted parameters and the activity data to generate an indication of effectiveness of the delivered cardiac resynchronization pacing pulses. - View Dependent Claims (18, 19)
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20. An implantable system comprising:
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means for delivering cardiac resynchronization pacing pulses to left and right ventricles of a patient'"'"'s heart to control synchronization of contractions of the left and right ventricles; means for collecting data associated with an evoked response of a patient from an intracardiac electrogram in response to the delivered cardiac resynchronization pacing pulses; means for extracting one or more parameters from the collected evoked response data; means for collecting data associated with activity of the patient; and means for cross correlating the one or more parameters and the collected activity data to generate an indication of effectiveness of the delivered cardiac resynchronization pacing pulses.
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Specification