Ultrasound apparatus and methods for mixing liquids and coating stents

• US 7,896,539 B2
• Filed: 08/16/2005
• Issued: 03/01/2011
• Est. Priority Date: 08/16/2005
• Status: Expired due to Fees

• Current Assignee: Bacoustics LLC
• Original Assignee: Bacoustics LLC
• Inventors: Babaev, Eilaz P.
• Primary Examiner(s): SOOHOO, TONY GLEN
• Application Number:
  US11/204,872
• Publication Number:
  US 20070051307A1
• Time in Patent Office: 2,023 Days
• Field of Search: 366108-128, 238/201.1
• US Class Current: 366/108
• CPC Class Codes: B05B 17/0623 coupled with a vibrating horn
• CPC Class Codes: B05B 17/063 having an internal channel for supplying the liquid or other fluent material

Abstract

Ultrasound methods and apparatus for mixing two or more different liquids are disclosed. The ultrasound methods and apparatus may mix varied components including drugs, polymers, and coatings for application to a variety of medical apparatus surfaces. The apparatus and technique can generate a proper mixture which is uninterruptedly/continuously delivered to the surface of the medical apparatus. The apparatus may include specific ultrasound transducer/tip configurations which may allow for the mixing of different liquids in a mixing camera located inside of the vibrating tip. The apparatus and methods of the present invention may mix different drugs, applying them to stent surface using different effects like ultrasound cavitation and radiation forces. Furthermore, the disclosed methods and apparatus may generate a mixture and may deliver a targeted, gentle, highly controllable dispensation of continuous liquid spray which can reduce the loss of expensive pharmaceuticals.

Claims

1. An apparatus for mixing comprising:

a. an ultrasound transducer having an ultrasonic horn;

b. the ultrasonic horn having a central axis and a distal end;

c. the ultrasonic horn also having a mixing chamber inside the ultrasonic horn having

i. a proximal wall,

ii. a distal wall,

iii. at least one radial wall and

iv. a rounded ultrasonic lens within the distal wall of the chamber;

d. at least one tube to deliver a fluid to the mixing chamber; and

e. the ultrasonic horn having an orifice at the distal end for discharging the fluid.

2. The apparatus of claim 1 in which the orifice for discharging the fluid has at least one thread.

3. The apparatus of claim 1 in which the tube is attached to the ultrasound horn approximately on a node point.

4. The apparatus of claim 1 in which the distal end of the horn has a geometric confirmation selected from the group consisting of convex, concave, tapered or flat.

5. The apparatus of claim 1 in which the proximal wall is flat.

6. The apparatus of claim 1 in which the proximal wall is convex.

7. The apparatus of claim 1 in which the distal wall is convex.

8. The apparatus of claim 1 in which the proximal wall is concave.

9. The apparatus of claim 1 in which the distal wall is concave.

10. The apparatus of claim 1 further comprising a gas supply in communication with the tube to deliver fluid into the chamber.

11. The apparatus of claim 1 further comprising a supply of heated fluid in communication with the tube to deliver fluid into the chamber.