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Methods of diagnosing Alzheimer's disease

  • US 7,897,361 B2
  • Filed: 09/29/2005
  • Issued: 03/01/2011
  • Est. Priority Date: 09/29/2004
  • Status: Active Grant
First Claim
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1. A method of diagnosing Alzheimer'"'"'s disease in a subject, the method comprising detecting a differentially expressed protein, said protein being clusterin precursor protein (Swiss-PROT Accession number (SPN) P10909), in a sample of blood or plasma from said subject, wherein a decrease in the expression of said clusterin precursor protein compared to the expression of said protein in a control subject is indicative of Alzheimer'"'"'s disease in the subject undergoing diagnosis.

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