Non-invasive tissue glucose level monitoring
First Claim
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1. A method of assessing a change in the structural matrix, cellular, or mitochondrial components of living tissue comprising:
- using a radiation source to expose living tissue to monochromatic radiation at about a first wavelength;
using the radiation source to expose living tissue to monochromatic radiation at about a second wavelength different from the first wavelength;
using a radiation detector to detect fluorescence emitted by the exposed living tissue in response to the radiation at about the first wavelength;
using the radiation detector to detect fluorescence emitted by the exposed living tissue in response to the radiation at about the second wavelength;
using a processing circuit to derive an indication representative of the change in the structural matrix of the living tissue based on the fluorescence detected;
using the radiation source to expose living tissue to broadband radiation;
using a scattering detector to detect scattering re-emitted from the exposed living tissue in response to the broadband radiation; and
using the processing circuit to derive the indication representative of the change in the structural matrix of the living tissue based also on the scattering detected.
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Abstract
Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.
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Citations
3 Claims
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1. A method of assessing a change in the structural matrix, cellular, or mitochondrial components of living tissue comprising:
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using a radiation source to expose living tissue to monochromatic radiation at about a first wavelength; using the radiation source to expose living tissue to monochromatic radiation at about a second wavelength different from the first wavelength; using a radiation detector to detect fluorescence emitted by the exposed living tissue in response to the radiation at about the first wavelength; using the radiation detector to detect fluorescence emitted by the exposed living tissue in response to the radiation at about the second wavelength; using a processing circuit to derive an indication representative of the change in the structural matrix of the living tissue based on the fluorescence detected; using the radiation source to expose living tissue to broadband radiation; using a scattering detector to detect scattering re-emitted from the exposed living tissue in response to the broadband radiation; and using the processing circuit to derive the indication representative of the change in the structural matrix of the living tissue based also on the scattering detected. - View Dependent Claims (2, 3)
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Specification