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Ultrasound energy driven intraventricular catheter to treat ischemia

  • US 7,901,359 B2
  • Filed: 12/06/2005
  • Issued: 03/08/2011
  • Est. Priority Date: 01/30/2001
  • Status: Expired due to Fees
First Claim
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1. An apparatus for stimulating angiogenesis in a biological tissue, comprising:

  • a catheter including a distal portion configured to be inserted into a body lumen of a patient;

    a tissue stimulating element at the distal portion of the catheter, the tissue stimulating element configured to radiate ultrasonic energy at a power that causes cellular damage to biological tissue and subsequent production of an angiogenesis stimulating substance;

    a power source that provides electrical energy to the tissue stimulating element; and

    a controller configured to control the temperature of the tissue stimulating element to a temperature at or below about 80 deg. C.,wherein the tissue stimulating element is configured to radiate the ultrasonic energy through a surface of the biological tissue to a region below the surface of the biological tissue at which the ultrasonic energy causes the cellular damage without causing substantial damage to the surface directly above the cellular damage.

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