Implantable sensor for measuring physiologic information

• US 7,901,360 B1
• Filed: 05/17/2007
• Issued: 03/08/2011
• Est. Priority Date: 05/17/2007
• Status: Expired due to Fees

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Yang, Michael, Hou, Wenbo
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Stice; Paula J
• Application Number:
  US11/750,226
• Time in Patent Office: 1,391 Days
• Field of Search: 600/508
• US Class Current: 600/508
• CPC Class Codes: A61B 2562/0261 Strain gauges
• CPC Class Codes: A61B 5/0295 using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
• CPC Class Codes: A61B 5/1107 Measuring contraction of parts of the body, e.g. organ, muscle apparatus for measuring work or force in general G01L
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/6869 Heart
• CPC Class Codes: A61B 5/688 using adhesives

Abstract

An implantable sensor is provided that includes a piezopolymer sensor element including a body having a plurality of layers of a piezopolymer, and an attachment device configured to hold the piezopolymer sensor element in direct contact with at least one of a bodily fluid and bodily tissue such that the piezopolymer sensor element is configured to bend in response to motion of the at least one of bodily fluid and bodily tissue. A pair of electrodes are attached to the piezopolymer sensor element and the electrodes are configured to collect an electrical charge that is generated within the piezopolymer sensor element due to the bending of the piezopolymer sensor element.

Claims

1. An implantable sensor comprising:

a piezopolymer sensor element comprising a body having a plurality of layers of a piezopolymer;

an attachment device configured to hold the piezopolymer sensor element in direct contact with at least one of a bodily fluid and bodily tissue such that the piezopolymer sensor element is configured to bend in response to motion of the at least one of bodily fluid and bodily tissue; and

a pair of electrodes attached to the piezopolymer sensor element, the electrodes configured to collect an electrical charge generated within the piezopolymer sensor element due to the bending of the piezopolymer sensor element;

wherein the attachment device comprises a cable defining an at least partially loop-shaped portion, the piezopolymer sensor element being held within an open space bounded by the loop-shaped portion.

2. The implantable sensor according to claim 1, wherein the piezopolymer sensor element comprises polyvinylidene fluoride (PVDF).

3. The implantable sensor according to claim 1, wherein the piezopolymer sensor element comprises at least one of an elongate beam shape, an elliptical shape, a square shape, and a tubular shape.

4. The implantable sensor according to claim 1, wherein the piezopolymer sensor element is a first piezopolymer sensor element, the implantable sensor further comprising a second piezopolymer sensor element held by the attachment device or another attachment device, the first and second piezopolymer sensor elements being held in approximately perpendicular orientation with respect to one another.

5. The implantable sensor according to claim 1, wherein the attachment device is configured to be positioned within a ventricle of the heart and to hold the piezopolymer sensor element in direct contact with blood flowing through the ventricle of the heart or in direct contact with an endocardial surface of the heart.

6. The implantable sensor according to claim 1, wherein the attachment device is configured to be positioned within pericardial space of the heart and to hold the piezopolymer sensor element in direct contact with an epicardial surface of the heart.

7. The implantable sensor according to claim 1, further comprising a lead, the attachment device forming an end portion of the lead.

8. The implantable sensor according to claim 1, further comprising a lead of at least one of a pulse generator, a pacemaker, an implantable cardioverter defibrillator, a defibrillator, and/or a therapy delivery module that at least one of paces and provides electrical stimulation to the heart.

9. The implantable sensor according to claim 1, wherein the attachment device comprises a generally cylindrical cable, the piezopolymer sensor element comprising a generally cylindrical shape, the piezopolymer sensor element being received on an exterior surface of the cable such that the piezopolymer sensor element at least partially surrounds a portion of the cable.

10. The implantable sensor according to claim 1, wherein the attachment device comprises a patch having a body portion configured to be attached to a surface of the heart.

11. The implantable sensor according to claim 1, further comprising a radio-frequency (RF) transmitter electrically connected to the electrodes for transmitting an electrical voltage output of the electrodes.

12. The implantable sensor of claim 1 wherein the sensor element and the loop-shaped portion lie in a common plane.

13. The implantable sensor of claim 1 further comprising a plurality of supports extending from the cable across the open space, wherein the supports attach to the sensor element to hold the sensor element in place within the open space.

14. An implantable sensor comprising:

a piezopolymer sensor element comprising a body having a plurality of layers of a piezopolymer;

an attachment device configured to hold the piezopolymer sensor element in direct contact with at least one of a bodily fluid and bodily tissue such that the piezopolymer sensor element is configured to bend in response to motion of the at least one of bodily fluid and bodily tissue; and

a pair of electrodes attached to the piezopolymer sensor element, the electrodes configured to collect an electrical charge generated within the piezopolymer sensor element due to the bending of the piezopolymer sensor element;

wherein the attachment device comprises a cable defining an at least partially diamond-shaped portion, the piezopolymer sensor element being held within an open space bounded by the diamond-shaped portion.

15. The implantable sensor of claim 14 wherein the diamond-shaped portion comprises one or more cable portions that lie in a common plane with the sensor element and one or more cable portions that bow outwardly from the common plane.

16. A method for measuring the motion of a heart, said method comprising:

positioning an attachment device with a sensor element within a pericardial space of a heart such that the sensor element is in direct contact with a surface of at least one of a serous pericardium of the pericardium and a fibrous pericardium of the pericardium such that the sensor element bends in response to motion of the at least one of a serous pericardium of the pericardium and a fibrous pericardium of the pericardium, wherein the attachment device comprises a cable defining an at least partially loop-shaped portion, the piezopolymer sensor element being held within an open space bounded by the loop-shaped portion;

measuring an output voltage of electrical charges generated on at least one surface of the sensor element due to the bending of the sensor element; and

determining a bending moment of the sensor element based on the measured output voltage.

17. The method according to claim 16, wherein positioning the sensor element comprises positioning first and second sensor elements in contact with the at least one of a serous pericardium of the pericardium and a fibrous pericardium of the pericardium and in an approximately perpendicular orientation with respect to one another.

18. The method according to claim 16, wherein positioning the sensor element comprises introducing the sensor element into the pericardial space of a heart through the subxiphoid.

19. The method according to claim 16, wherein positioning the sensor element comprises incorporating the sensor element into a lead of at least one of a pulse generator, a pacemaker, an implantable cardioverter defibrillator, a defibrillator, and/or a therapy delivery module that at least one of paces and provides electrical stimulation to the heart.

20. The method according to claim 16, wherein positioning a sensor element comprises positioning a piezopolymer sensor element.

21. The method according to claim 16, further comprising determining information relating to the motion of the at least one of a serous pericardium of the pericardium and a fibrous pericardium of the pericardium based on a determined bending moment.