Modulation of AV delay to control ventricular interval variability
First Claim
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1. A method of delivering pacing therapy to a heart, comprising:
- determining a base atrioventricular (AV) delay as a function of heart rate;
for each cardiac cycle, modulating the base AV delay to reduce beat-to-beat variability of successive ventricular beats, the modulated AV delay compensating for variability of successive atrial beats, wherein modulating the base AV delay comprises varying the AV delay inversely with a change in atrial interval; and
delivering the pacing therapy using the modulated AV delay.
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Abstract
System and methods provide pacing therapy that modulates the atrioventricular (AV) delay to control ventricular interval variability. A base AV delay is determined as a function of heart rate. For each cardiac cycle, the base AV delay is modulated to reduce beat-to-beat variability of successive ventricular beats. The modulated AV delay compensates for variability of successive atrial beats. For example, modulation of the base AV delay may involve varying the AV delay inversely with a change in atrial interval.
54 Citations
19 Claims
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1. A method of delivering pacing therapy to a heart, comprising:
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determining a base atrioventricular (AV) delay as a function of heart rate; for each cardiac cycle, modulating the base AV delay to reduce beat-to-beat variability of successive ventricular beats, the modulated AV delay compensating for variability of successive atrial beats, wherein modulating the base AV delay comprises varying the AV delay inversely with a change in atrial interval; and delivering the pacing therapy using the modulated AV delay. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A cardiac rhythm management system, comprising:
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electrodes electrically coupled to a heart; a therapy controller configured to determine a base atrioventricular (AV) delay as a function of heart rate, and for each cardiac cycle, modulate the base AV delay inversely with a change in atrial interval to reduce beat-to-beat variability in ventricular intervals; and a pacing therapy delivery circuit coupled to the pacing controller and the electrodes, the pacing therapy delivery circuit configured to deliver pacing therapy via the electrodes using the modulated AV delay. - View Dependent Claims (13, 14, 15, 16)
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17. A system for delivering pacing therapy to a heart, comprising:
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means for determining a base atrioventricular (AV) delay as a function of heart rate; means for modulating the base AV delay for each cardiac cycle to reduce beat-to-beat variability of successive ventricular beats, the modulated AV delay compensating for variability of successive atrial beats, wherein the means for modulating the base AV delay comprises means for varying the AV delay inversely with a change in atrial interval; and means for delivering the pacing therapy using the modulated AV delay. - View Dependent Claims (18, 19)
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Specification