System and method for improved low flow medical pump delivery

• US 7,905,710 B2
• Filed: 08/25/2006
• Issued: 03/15/2011
• Est. Priority Date: 03/26/2004
• Status: Active Grant

• Current Assignee: ICU Medical Incorporated
• Original Assignee: Hospira Incorporated (Pfizer Inc.)
• Inventors: Greene, Howard L., Cousineau, Robert P., Wang, David T., Navin, Eric R., Lucke, Lori E., Saleki, Mansour A., Boyd, Robert R., Kidd, Brian A., Lawless, Michael W., Abrahamson, Kent D., Mullin, Benjamin T., Scaramuzzi, Peter J., Fathallah, Marwan A.
• Primary Examiner(s): FREAY, CHARLES GRANT
• Application Number:
  US11/510,106
• Publication Number:
  US 20070058412A1
• Time in Patent Office: 1,663 Days
• Field of Search: 417/12, 417/18, 417/53, 604/151, 604/153, 604/246, 700/282
• US Class Current: 417/18
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: A61M 5/16809 by repeated filling and emptying of an intermediate volume pressure infusion using positive displacement pumps A61M5/142
• CPC Class Codes: A61M 5/16854 by monitoring line pressure
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence

Abstract

A medical pump with an improved continuity low flow delivery system and method for use with a pumping chamber, for example in a cassette, is disclosed. The pump includes a pump drive for exerting a force on the pumping chamber and a sensor for sensing the force/pressure exerted by the pump drive on the pumping chamber. The pump drive position sensor senses the position of the pump drive. The medical pump also includes a processing unit and a memory having a programming code adapted to calculate the rate of change of the sensed force/pressure values and determine whether the rate of change of the sensed force/pressure values meets a rate of change threshold. Once the rate of change threshold is met, the programming code is adapted to calculate a remaining pump drive travel value for determining how much farther the pump drive should travel before the end of an effective pump cycle. The programming code is further adapted to trigger one or more signals to drive the pump drive for the remainder of the effective pump cycle using the remaining pump drive travel value.

Claims

1. A method for providing low flow continuity of a medical pump having a pump drive and a force/pressure sensor, comprising the steps of:

determining a cycle start position;

driving the pump drive at a drive rate which is based on a desired delivery rate;

sensing a plurality of force/pressure values over time using the force/pressure sensor, which are representative of the force/pressure exerted on the force/pressure sensor as the driving of the pump drive occurs;

calculating the rate of change of the sensed force/pressure values;

determining in a first determination step whether the rate of change of the sensed force/pressure values meets a first rate of change value;

if the first determination step is true, determining in a second determination step whether the rate of change of the sensed force/pressure values meets a second rate of change value;

if the second determination step is true, calculating a remaining pump drive travel value for determining how much farther the pump drive should travel before the end of an effective pump cycle; and

,

completing the effective pump cycle delivery using the remaining pump drive travel value.

2. The method of claim 1 further comprising continuously detecting the position of the pump drive.

3. The method of claim 1 wherein the step of calculating the remaining pump drive travel value comprises the steps of:

providing an effective cycle travel value;

determining an already traveled cycle value when the second determination step is true; and

,

subtracting the already traveled cycle value from the effective cycle travel value.

4. The method of claim 3 further comprising the step of determining a pump drive step value to complete the effective cycle by dividing the remaining pump drive travel value by a step travel size value.

5. The method of claim 1 wherein the drive rate is selected from a group consisting of a constant rate and a variable rate.

6. The method of claim 1 wherein the first and second rate of change values are both predetermined values, wherein the first determination step comprises determining whether the rate of change of the sensed force/pressure values is greater than the first rate of change value, wherein the second determination step comprises whether the rate of change of the sensed force/pressure values is less than a second rate of change value, and wherein the first rate of change value is less than the second rate of change value.

7. The method of claim 1 further comprising the step of calculating the first and second rate of change values.

8. The method of claim 1 wherein the first and second rate of change values are calculated as predetermined percentages of a highest rate of change value from a previous cycle.

9. The method of claim 1 wherein the pump drive is provided for driving a cam which drives a plunger for exerting a force/pressure within a pumping chamber.

10. The method of claim 1 wherein the cycle comprises a pressurization phase, a pumping phase, and a retraction phase.

11. The method of claim 1 wherein the pump drive is retracted to the cycle start position after a pumping phase is completed.

12. The method of claim 1 wherein the step of calculating the predetermined drive rate to drive the pump drive is based on a cycle calibration value.

13. The method of claim 1 further comprising the step of determining whether the pump drive has traveled beyond a minimum allowable pump drive travel value for a cycle.

14. The method of claim 1 further comprising the step of determining whether the pump drive has traveled beyond a maximum allowable pump drive travel value for a cycle.

15. The method of claim 1 further comprising the steps of:

storing the plurality of sensed force/pressure values; and

,

calculating an average force/pressure value for each of a plurality of time intervals, and using the averaged force/pressure values to determine the rate of change of the sensed force/pressure values.

16. The method of claim 1 further comprising the steps of:

determining whether a predetermined initial travel value has been met in relation to the cycle start position; and

,

preventing at least one of the following steps until the predetermined initial travel value has been met;

a) the first determination step;

b) the step of sensing the plurality of force/pressure values;

c) the step of calculating the rate of change of the sensed force/pressure values; and

/or,

d) the step of calculating the remaining pump drive travel value.

17. The method of claim 1 further comprising the steps of:

determining whether an additional travel value has been met after the first determination step is true; and

,

preventing at least one of the following steps until the additional travel value has been met;

a) the second determination step;

b) the step of sensing the plurality of force/pressure values;

c) the step of calculating the rate of change of the sensed force/pressure values; and

/or,

d) the step of calculating the remaining pump drive travel value.

19. The method of claim 16 wherein the initial travel value is selected from a group consisting of a time and a distance.

18. A method for providing low flow continuity of a medical pump having a pump drive and a force/pressure sensor, comprising the steps of:

determining a cycle start position;

driving the pump drive at a drive rate which is based on a desired delivery rate;

sensing a plurality of force/pressure values over time using the force/pressure sensor, which are representative of the force/pressure exerted on the force/pressure sensor as the driving of the pump drive occurs;

determining whether a predetermined initial travel value has been met in relation to the cycle start position;

calculating the rate of change of the sensed force/pressure values;

if the rate of change of the sensed force/pressure values is less than the threshold rate of change value, calculating a remaining pump drive travel value for determining how much farther the pump drive should travel before the end of an effective pump cycle;

preventing at least one of the following steps until a predetermined initial travel value has been met;

a) sensing the plurality of force/pressure values;

b) calculating the rate of change of the sensed force/pressure values;

determining whether the rate of change of the sensed force/pressure values is less than a threshold rate of change value; and

/or,

c) calculating the remaining pump drive travel value; and

,

completing the effective pump cycle delivery using the remaining pump drive travel value.

20. A method for providing low flow continuity of a medical pump having a pump drive and a force/pressure sensor, comprising the steps of:

determining a cycle start position;

driving the pump drive at a drive rate which is based on a desired delivery rate;

sensing a plurality of force/pressure values using the force/pressure sensor, which are representative of the force/pressure exerted on the force/pressure sensor as the driving of the pump drive occurs;

calculating the rate of change of the sensed force/pressure values;

determining whether the rate of change of the sensed force/pressure values has met a threshold rate of change value;

if the rate of change of the sensed force/pressure values has met the threshold rate of change value, then at least one of determining whether a predetermined further travel value has been met and/or driving the pump drive based on the predetermined further travel value;

if the predetermined further travel value has been met and/or fulfilled, then calculating a remaining pump drive travel value for determining how much farther the pump drive should travel before the end of an effective pump cycle; and

,

completing the effective pump cycle delivery using the remaining pump drive travel value.

21. A method for providing low flow continuity of a medical pump having a pump drive and a force/pressure sensor, comprising the steps of:

determining a delivery cycle start position;

determining the amount of a substance remaining to be delivered;

driving the pump drive at a drive rate which is based on a desired delivery rate;

sensing a plurality of force/pressure values over a travel distance using the force/pressure sensor, which are representative of the force/pressure exerted on the force/pressure sensor as the driving of the pump drive occurs;

determining the rate of change of the sensed force/pressure values over the travel distance;

determining in a first determination step whether the rate of change of the sensed force/pressure values meets a first rate of change value;

if the first determination step is true, determining whether the amount of the substance remaining to be delivered has changed; and

,

if the amount of the substance remaining to be delivered has changed more than a change threshold, completing the delivery cycle.

22. The method of claim 21 wherein the amount of the substance is selected from a group consisting of a weight and a volume.

23. The method of claim 21 further comprising the step of:

if the amount of the substance remaining has not changed more than the change threshold, then driving the pump drive in a reverse direction for unsticking the substance delivery.

24. The method of claim 23 further comprising the step of:

if the amount of the substance remaining has not changed more than the change threshold, then alternating the driving of the pump drive in a forward direction and the reverse direction a plurality of times within a time interval for unsticking the substance delivery.

25. The method of claim 21 further comprising the steps of:

determining in a second determination step whether the rate of change of the sensed force/pressure values meets a second rate of change value; and

,

if the second determination step is true, determining whether the amount of the substance remaining to be delivered has changed.

26. A method for providing low flow continuity of a medical pump having a pump drive and a force/pressure sensor, comprising the steps of:

determining a cycle start position;

driving the pump drive at a drive rate which is based on a desired delivery rate;

sensing a plurality of force/pressure values using the force/pressure sensor, which are representative of the force/pressure exerted on the force/pressure sensor as the driving of the pump drive occurs;

determining a delivery start position by calculating the rate of change of the sensed force/pressure values and determining the delivery start position when a rate of change threshold has been met;

calculating the remaining pump drive travel value in relation to the delivery start position, comprising the steps of;

receiving an effective cycle travel value;

determining an already traveled cycle value based on the delivery start position; and

,

subtracting the already traveled cycle value from the effective cycle travel value; and

,

driving the pump drive using the remaining pump drive travel value.

27. A medical pump for low flow delivery of a substance, for use with a pumping chamber, comprising:

a pump drive for exerting a force on the pumping chamber;

a sensor operatively associated with the pump drive for sensing the force/pressure exerted by the pump drive on the pumping chamber;

a pump drive position sensor operatively connected to the pump drive for sensing the position of the pump drive;

a processor in electronic communication with the pump drive, the force/pressure sensor, and the pump drive position sensor;

a memory in electronic communication with the processor, wherein the memory comprises programming code for execution by the processor, and wherein the programming code is adapted to;

calculate the rate of change of the sensed force/pressure values over time;

determine in a first determination step whether the rate of change of the sensed force/pressure values meets a first rate of change value;

if the first determination step is true, determine in a second determination step whether the rate of change of the sensed force/pressure values meets than a second rate of change value;

if the second determination step is true, calculate a remaining pump drive travel value for determining how much farther the pump drive should travel before the end of an effective pump cycle; and

,

trigger a plurality of pump drive signals for driving the pump drive for the remainder of the effective pump cycle using the remaining pump drive travel value.

28. The medical pump of claim 27, wherein the pump drive comprises a stepper motor, and wherein the programming code is further adapted to determine a motor step size value for driving the stepper motor according to the motor step size value.

29. The medical pump of claim 27, wherein the pump drive comprises a stepper motor, and wherein the programming code is further adapted to receive a set motor RPM value for use in calculating the remaining pump drive travel value.

30. The medical pump of claim 27, wherein the programming code is further adapted to calculate an estimated incremental delivery volume.

31. The medical pump of claim 27, wherein the pump drive drives a pumping element for exerting a force on the pumping chamber.

32. The medical pump of claim 27, wherein the pumping chamber is a portion of at least one of a cassette, a tube, and/or a syringe.

33. The medical pump of claim 27 wherein the pump drive position sensor has a resolution of from about 0.15 mils to about 0.45 mils.

34. A medical pump for low flow delivery of a substance, for use with a pumping chamber, comprising:

a pump drive for exerting a force on the pumping chamber;

a sensor operatively associated with the pump drive for sensing the force/pressure exerted by the pump drive on the pumping chamber;

a pump drive position sensor operatively connected to the pump drive for sensing the position of the pump drive;

a processor in electronic communication with the pump drive, the force/pressure sensor, and the pump drive position sensor;

a memory in electronic communication with the processor, wherein the memory comprises programming code for execution by the processor, and wherein the programming code is adapted to;

determine a cycle start position;

calculate the rate of change of the sensed force/pressure values;

determine whether a predetermined initial travel value has been met in relation to the cycle start position;

prevent at least one of the following steps until the predetermined initial travel value has been met;

a) sense the plurality of force/pressure values; and

/or,

b) calculate the rate of change of the sensed force/pressure values;

determine whether the rate of change of the sensed force/pressure values is less than a threshold rate of change value;

if the rate of change of the sensed force/pressure values is less than the threshold rate of change value, calculate a remaining pump drive travel value for determining how much farther the pump drive should travel before the end of an effective pump cycle; and

,

trigger a plurality of pump drive signals for driving the pump drive for the remainder of the effective pump cycle using the remaining pump drive travel value.

35. A medical pump for low flow delivery of a substance, for use with a pumping chamber, comprising:

a pump drive for exerting a force on the pumping chamber;

a sensor operatively associated with the pump drive for sensing the force/pressure exerted by the pump drive on the pumping chamber;

a pump drive position sensor operatively connected to the pump drive for sensing the position of the pump drive;

a processor in electronic communication with the pump drive, the force/pressure sensor, and the pump drive position sensor;

a memory in electronic communication with the processor, wherein the memory comprises programming code for execution by the processor, and wherein the programming code is adapted to;

determine a cycle start position;

calculate the rate of change of the sensed force/pressure values;

determine whether the rate of change of the sensed force/pressure values has met a threshold rate of change value;

if the rate of change of the sensed force/pressure values has met the threshold rate of change value, then at least one of determine whether a predetermined further travel value has been met and/or drive the pump drive based on the predetermined further travel value;

if the predetermined further travel value has been met or fulfilled, then calculate a remaining pump drive travel value in order to determine how much farther the pump drive should travel before the end of an effective pump cycle; and

,

trigger a plurality of pump drive signals for driving the pump drive for the remainder of the effective pump cycle using the remaining pump drive travel value.

36. A medical pump for low flow delivery of a substance, for use with a pumping chamber, comprising:

a pump drive for exerting a force on the pumping chamber;

a sensor operatively associated with the pump drive for sensing the force/pressure exerted by the pump drive on the pumping chamber;

a pump drive position sensor operatively connected to the pump drive for sensing the position of the pump drive;

a processor in electronic communication with the pump drive, the force/pressure sensor, and the pump drive position sensor;

a memory in electronic communication with the processor, wherein the memory comprises programming code for execution by the processor, and wherein the programming code is adapted to;

receive a delivery cycle start position;

determine the amount of the substance remaining to be delivered;

determine the rate of change of the sensed force/pressure values over the travel distance;

determine in a first determination step whether the rate of change of the sensed force/pressure values meets a first rate of change value;

if the first determination step is true, determine whether the amount of the substance remaining to be delivered has changed; and

,

if the amount of the substance remaining to be delivered has changed more than a change threshold, trigger a plurality of pump drive signals for driving the pump drive for the remainder of the effective pump cycle using the remaining pump drive travel value.

37. A medical pump for low flow delivery of a substance, for use with a pumping chamber, comprising:

a pump drive for exerting a force on the pumping chamber;

a sensor operatively associated with the pump drive for sensing the force/pressure exerted by the pump drive on the pumping chamber;

a pump drive position sensor operatively connected to the pump drive for sensing the position of the pump drive;

a processor in electronic communication with the pump drive, the force/pressure sensor, and the pump drive position sensor;

a memory in electronic communication with the processor, wherein the memory comprises programming code for execution by the processor, and wherein the programming code is adapted to;

receive a cycle start position;

determine a delivery start position by calculating the rate of change of the sensed force/pressure values and determine the delivery start position when a rate of change threshold has been met;

calculate the remaining pump drive travel value in relation to the delivery start position, comprising the steps of;

receive an effective cycle travel value representative of an effective cycle travel;

determine an already traveled cycle value based on the delivery start position; and

,

subtract the already traveled cycle value from the effective cycle travel value; and

,

trigger a plurality of pump drive signals for driving the pump drive for the remainder of the effective cycle travel using the remaining pump drive travel value.

38. A medical pump for low flow delivery of a substance, for use with a pumping chamber, comprising:

a pump drive for exerting a force on the pumping chamber;

a sensor operatively associated with the pump drive for sensing the force/pressure exerted by the pump drive on the pumping chamber;

a pump drive position sensor operatively connected to the pump drive for sensing the position of the pump drive;

a processor in electronic communication with the pump drive, the force/pressure sensor, and the pump drive position sensor;

a memory in electronic communication with the processor, wherein the memory comprises programming code for execution by the processor, and wherein the programming code is adapted to;

calculate the rate of change of the sensed force/pressure values;

determine in a first determination step whether the rate of change of the sensed force/pressure values meets a first rate of change value;

if the first determination step is true, at least one of calculate a remaining pump drive travel value and/or determine whether the amount of the substance remaining to be delivered has changed; and

,

trigger a plurality of pump drive signals for driving the pump drive for the remainder of the effective pump cycle.

39. The medical pump of claim 38 wherein calculating a remaining pump drive travel value is performed for determining how much farther the pump drive should travel before the end of an effective pump cycle.

40. The medical pump of claim 38 wherein the step of triggering the plurality of pump drive signals uses the remaining pump drive travel value to trigger the plurality of pump drive signals.

41. The medical pump of claim 38 wherein the programming code is further adapted to:

receive a delivery cycle start position;

determine the amount of the substance remaining to be delivered; and

,

if the amount of the substance remaining to be delivered has changed more than a change threshold, trigger the plurality of pump drive signals for driving the pump drive for the remainder of the effective pump cycle using the remaining pump drive travel value.