Biosensor

• US 7,905,998 B2
• Filed: 01/31/2008
• Issued: 03/15/2011
• Est. Priority Date: 09/12/1997
• Status: Expired due to Fees

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Inventors: Mure, Hiroki, Shirakawa, Hiroshi, Gotoh, Masao
• Primary Examiner(s): NOGUEROLA, ALEXANDER STEPHAN
• Application Number:
  US12/068,015
• Publication Number:
  US 20080251378A1
• Time in Patent Office: 1,139 Days
• Field of Search: 20440301-40315, 205/777.5, 205/778, 205/792
• US Class Current: 204/403.02
• CPC Class Codes: C12Q 1/005 involving specific analytes or enzymes including groups of enzymes, e.g. oxydases; C12Q1/004 takes precedence
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: Y10S 435/817 Enzyme or microbe electrode

Abstract

A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in the peripheral part and partially closed by the adhesive layer, and has a working electrode having at least glucose oxidase immobilized thereon and a counter electrode on the same plane of the plate.

Claims

1. A biosensor comprising:

a proximal end and a distal end, the proximal end comprising a sample receiving space and the distal end for connecting to a device body;

a first layer comprising a first part of an electrode disposed thereon;

a second layer comprising a second part of the electrode disposed thereon;

a contact transfer component associating the first part of the electrode with the second part of the electrode; and

an insertion judging electrode disposed on the first layer or the second layer, wherein the insertion judging electrode is disposed only at the distal end, wherein the insertion judging electrode interconnects two input terminals of the device body to start a control part of the device body upon connecting the biosensor to the device body.

2. The biosensor of claim 1, wherein the contact transfer component comprises a third layer of the biosensor.

3. The biosensor of claim 2, wherein the third layer is an adhesive layer.

4. The biosensor of claim 2, third layer comprises a bore therethrough and the contact is achieved through the bore.

5. The biosensor of claim 2, wherein the sample receiving space is provided between the first and second layers, and the sample receiving space has a volume that is no more than about 0.5 μ

L.

6. The biosensor of claim 1, wherein the contact transfer component comprises a conductor.

7. The biosensor of claim 6, wherein the conductor comprises silver or carbon.

8. The biosensor of claim 1, wherein said the first and second layers include an end having a tapered part.

9. The biosensor of claim 8, wherein said electrode is a working electrode having a tip part, wherein said tip part of the working electrode is provided on said tapered part.

10. The biosensor of claim 8, further comprising a reference electrode and a tip part of the reference electrode is provided on the tapered part.

11. The biosensor of claim 8, wherein the tapered part includes an opening for admitting the sample to the sample receiving space.

12. The biosensor of claim 1, wherein the electrode is a working electrode, the biosensor further comprising a counter electrode.

13. The biosensor of claim 12, wherein the working and counter electrodes are separated by a space from about 100 μ

m to about 500 μ

m.

14. The biosensor of claim 12, wherein the working electrode and the counter electrode are provided on different layers.

15. The biosensor of claim 1, wherein said electrode is constructed of a gold material.

16. The biosensor of claim 1, further comprising an analyte-responsive enzyme.

17. The biosensor of claim 16, wherein the analyte-responsive enzyme comprises of at least one of glucose oxidase or glucose dehydrogenase.

18. The biosensor of claim 1, wherein the electrode is a working electrode, the biosensor further comprising a counter electrode, and wherein the counter electrode is provided on the first layer.

19. The biosensor of claim 18, wherein said same layer is the first layer and a length of the first layer is greater than a length of the second layer.

20. The biosensor of claim 1, wherein the electrode is a working electrode, and wherein the biosensor comprises a counter electrode and a reference electrode and wherein the working, counter, and reference electrodes are provided on a same layer.

21. The biosensor of claim 1, wherein the insertion judging electrode is substantially rectangular in shape.