Anti-infectious, biocompatible titanium coating for implants, and method for the production thereof
First Claim
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1. A method for the preparation of a titanium oxide coating on an implant comprising the steps of:
- a) forming a preparation comprising an organic solvent, an organometallic titanium oxide precursor and metal ions as metal salts and/or organometallic compounds, wherein the preparation is a sol in which the metal ions are homogeneously dispersed and dissolved, and wherein the metal ions are selected from the group consisting of zinc, mercury, vanadium, aluminum, chromium, cadmium, tin, lead, nickel, cobalt, calcium, magnesium, copper, and silver;
b) applying the preparation prepared in a) onto an implant to form a coating;
c) drying the coating, wherein the metal ions in the coating exert an anti-microbial or antibacterial effect under physiological conditions.
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Abstract
The present invention relates to a method for the preparation of a biocompatible metal ion-containing titanium oxide coating on an implant wherein the metal ions can be eluted under physiological conditions and are homogeneously dispersed within the coating, as well as to an implant which can be prepared according to the method of the present invention.
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Citations
30 Claims
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1. A method for the preparation of a titanium oxide coating on an implant comprising the steps of:
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a) forming a preparation comprising an organic solvent, an organometallic titanium oxide precursor and metal ions as metal salts and/or organometallic compounds, wherein the preparation is a sol in which the metal ions are homogeneously dispersed and dissolved, and wherein the metal ions are selected from the group consisting of zinc, mercury, vanadium, aluminum, chromium, cadmium, tin, lead, nickel, cobalt, calcium, magnesium, copper, and silver; b) applying the preparation prepared in a) onto an implant to form a coating; c) drying the coating, wherein the metal ions in the coating exert an anti-microbial or antibacterial effect under physiological conditions. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification