Lyophilized formulations of exendins and exendin agonist analogs
First Claim
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1. A lyophilized formulation comprising about 0.005% (w/v) to about 0.4% (w/v) exendin-4 and about 1.0% (w/v) to about 10% (w/v) mannitol.
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Abstract
Novel formulations containing exendins, exendin agonists and/or exendin analogs are provided.
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Citations
20 Claims
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1. A lyophilized formulation comprising about 0.005% (w/v) to about 0.4% (w/v) exendin-4 and about 1.0% (w/v) to about 10% (w/v) mannitol.
- 2. A lyophilized formulation comprising about 0.005% (w/v) to about 0.4% (w/v) of exendin-4 or an exendin agonist analog thereof and about 1.0% (w/v) to about 10% (w/v) of one or more compounds selected from the group consisting of mannose, ribose, trehalose, maltose, glycerol, inositol, glucose, lactose, galactose, arabinose, sorbitol, mannitol, glycerol, xylitol, a polypropylene/ethylene glycol copolymer, and a polyethylene glycol.
- 6. A lyophilized formulation comprising about 0.005% (w/v) to about 0.4% (w/v) of exendin-4 or an exendin agonist analog thereof and about 1.0% (w/v) to about 10% (w/v) of a bulking agent.
Specification