Method and apparatus for penetrating tissue
First Claim
Patent Images
1. A tissue penetrating system, comprising:
- a housing member;
a plurality of penetrating members positioned in the housing member,a plurality of sample chambers, each of a sample chamber associated with a penetrating member, each of a sample chamber including non-optical electrode analyte detecting members and having a volume no greater than 1 μ
L and, the sample chamber being positioned to receive fluid from a wound created by a penetrating member and determine a concentration of an analyte in the fluid using a sample of less than 1 μ
L of the fluid, wherein when the penetrating member is removed from the sample chamber, the electrodes remain in the sample chamber and a volume of the sample chamber is less than 1 μ
L;
a penetrating member driver coupled to and for driving each of the plurality of penetrating members;
a penetrating member transport device for moving each of the plurality of penetrating members into a position for alignment with the penetrating member driver;
a processor configured to control the penetrating member driver and the penetrating member transport device to drive the plurality of penetrating members and determine that a penetrating member has contacted a skin surface, and in response the processor adjusting a speed of the penetrating member or the power delivered to the penetrating member for skin penetration to maintain a desired penetration velocity of the penetrating member, the processor determining whether a distal end of the penetrating member has reached a brake depth to achieve a desired final penetration depth of the penetrating member, wherein the processor uses a determination of skin contact by the penetrating member as a consideration of skin tenting by the penetrating member, wherein skin tenting is used as a consideration factor for brake depth, wherein the processor determines whether a distal end of the penetrating member has reached a brake depth based on an amount of said skin tenting, the brake depth being either pre-determined and programmed into the processor or the processor dynamically determines the brake depth during actuation and the processor causes a braking force to be applied to penetrating member and provide for a reduction in pain; and
a tissue stabilizing member coupled to the housing and configured to enhance spontaneous fluid flow from the target tissue to the sample chamber and provide a volume of fluid flow of about no more than 1 μ
L.
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Accused Products
Abstract
A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.
2883 Citations
35 Claims
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1. A tissue penetrating system, comprising:
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a housing member; a plurality of penetrating members positioned in the housing member, a plurality of sample chambers, each of a sample chamber associated with a penetrating member, each of a sample chamber including non-optical electrode analyte detecting members and having a volume no greater than 1 μ
L and, the sample chamber being positioned to receive fluid from a wound created by a penetrating member and determine a concentration of an analyte in the fluid using a sample of less than 1 μ
L of the fluid, wherein when the penetrating member is removed from the sample chamber, the electrodes remain in the sample chamber and a volume of the sample chamber is less than 1 μ
L;a penetrating member driver coupled to and for driving each of the plurality of penetrating members; a penetrating member transport device for moving each of the plurality of penetrating members into a position for alignment with the penetrating member driver; a processor configured to control the penetrating member driver and the penetrating member transport device to drive the plurality of penetrating members and determine that a penetrating member has contacted a skin surface, and in response the processor adjusting a speed of the penetrating member or the power delivered to the penetrating member for skin penetration to maintain a desired penetration velocity of the penetrating member, the processor determining whether a distal end of the penetrating member has reached a brake depth to achieve a desired final penetration depth of the penetrating member, wherein the processor uses a determination of skin contact by the penetrating member as a consideration of skin tenting by the penetrating member, wherein skin tenting is used as a consideration factor for brake depth, wherein the processor determines whether a distal end of the penetrating member has reached a brake depth based on an amount of said skin tenting, the brake depth being either pre-determined and programmed into the processor or the processor dynamically determines the brake depth during actuation and the processor causes a braking force to be applied to penetrating member and provide for a reduction in pain; and a tissue stabilizing member coupled to the housing and configured to enhance spontaneous fluid flow from the target tissue to the sample chamber and provide a volume of fluid flow of about no more than 1 μ
L. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A tissue penetrating system, comprising:
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a housing member; a plurality of penetrating members positioned in the housing member, a plurality of sample chambers, each of a sample chamber associated with a penetrating member, each of a sample chamber including non-optical electrode analyte detecting members and having a volume no greater than 1 μ
L and, the sample chamber being positioned to receive fluid from a wound created by a penetrating member and determine a concentration of an analyte in the fluid using a sample of less than 1 μ
L of the fluid, wherein when the penetrating member is removed from the sample chamber, the electrodes remain in the sample chamber and a volume of the sample chamber is less than 1 μ
L;a penetrating member driver coupled to and for driving each of the plurality of penetrating members; a penetrating member transport device for moving each of the plurality of penetrating members into a position for alignment with the penetrating member driver; a processor coupled to a position sensor for controlling the penetrating member driver and the penetrating member transport device to drive the plurality of penetrating members and for determining that a penetrating member has contacted a skin surface, and in response the processor adjusts a speed of the penetrating member or the power delivered to the penetrating member for skin penetration to maintain a desired penetration velocity of the penetrating member, the processor determining whether a distal end of the penetrating member has reached a brake depth to achieve a desired final penetration depth of the penetrating member, wherein the processor uses a determination of skin contact by the penetrating member as a consideration of skin tenting by the penetrating member, wherein skin tenting is used as a consideration factor for brake depth, wherein the processor determines whether a distal end of the penetrating member has reached a brake depth based on an amount of said skin tenting, the brake depth being either pre-determined and programmed into the processor or the processor dynamically determines the brake depth during actuation and the processor causes a braking force to be applied to penetrating member and provide for a reduction in pain; the final penetration depth being selected to provide that a sample volume of less than 1 μ
L is received in a sample chamber with a spontaneous flow of sample.
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16. A tissue penetrating system, comprising:
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a housing member; a plurality of penetrating members positioned in the housing member, a plurality of non-optical analyte sensors; a tissue stabilizing member coupled to the housing and configured to enhance spontaneous fluid flow from the target tissue to a sample chamber; a penetrating member driver coupled to and for driving each of the plurality of penetrating members; a penetrating member transport device for moving each of the plurality of penetrating members into a position for alignment with the penetrating member driver; a processor coupled to a position sensor for controlling the penetrating member driver and the penetrating member transport device to drive the plurality of penetrating members and for determining that a penetrating member has contacted a skin surface, and in response the processor adjusts a speed of the penetrating member or the power delivered to the penetrating member for skin penetration to maintain a desired penetration velocity of the penetrating member, the processor determining whether a distal end of the penetrating member has reached a brake depth to achieve a desired final penetration depth of the penetrating member, wherein the processor uses a determination of skin contact by the penetrating member as a consideration of skin tenting by the penetrating member, wherein skin tenting is used as a consideration factor for brake depth, wherein the processor determines whether a distal end of the penetrating member has reached a brake depth based on an amount of said skin tenting, the brake depth being either pre-determined and programmed into the processor or the processor dynamically determines the brake depth during actuation and the processor causes a braking force to be applied to penetrating member and provide for a reduction in pain; the final penetration depth being selected to provide that a sample volume of less than 1 μ
L is received in a sample chamber. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35)
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Specification