Methods of administering pirfenidone therapy
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1. A method of administering pirfenidone therapy to a patient in need thereof, comprising administering to the patient a therapeutically effective amount of pirfenidone while avoiding co-administration of a strong cytochrome P450 1A2 (CYP1A2) inhibitor, wherein said patient is also in need of therapy with a strong CYP1A2 inhibitor.
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Abstract
The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors of CYP enzymes.
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- 1. A method of administering pirfenidone therapy to a patient in need thereof, comprising administering to the patient a therapeutically effective amount of pirfenidone while avoiding co-administration of a strong cytochrome P450 1A2 (CYP1A2) inhibitor, wherein said patient is also in need of therapy with a strong CYP1A2 inhibitor.
- 5. A method of administering pirfenidone therapy to a patient in need thereof, comprising discontinuing administration of a strong CYP1A2 inhibitor to avoid an adverse drug interaction with pirfenidone, and administering to the patient a therapeutically effective amount of pirfenidone.
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