Method and apparatus for pumping blood

• US 7,914,436 B1
• Filed: 06/12/2006
• Issued: 03/29/2011
• Est. Priority Date: 06/12/2006
• Status: Active Grant

• Current Assignee: Abiomed, Inc. (Johnson & Johnson)
• Original Assignee: Abiomed, Inc. (Johnson & Johnson)
• Inventors: Kung, Robert T. V.
• Primary Examiner(s): Manuel; George
• Assistant Examiner(s): Wieland; Robert N
• Application Number:
  US11/451,221
• Time in Patent Office: 1,751 Days
• Field of Search: 417/394, 600/18, 600/16, 604/102.01, 604/264, 604/153, 604/509
• US Class Current: 600/18
• CPC Class Codes: A61M 60/139 inside the aorta, e.g. intra-aortic balloon pumps
• CPC Class Codes: A61M 60/274 the inlet and outlet being the same, e.g. para-aortic counter-pulsation blood pumps
• CPC Class Codes: A61M 60/295 Balloon pumps for circulatory assistance
• CPC Class Codes: A61M 60/497 for balloon pumps for circulatory assistance
• CPC Class Codes: A61M 60/515 Regulation using real-time patient data
• CPC Class Codes: A61M 60/861 Connections or anchorings for connecting or anchoring pumps or pumping devices to parts of the patient's body
• CPC Class Codes: A61M 60/865 Devices for guiding or inserting pumps or pumping devices into the patient's body
• CPC Class Codes: A61M 60/896 having flexible or resilient parts, e.g. flap valves

Abstract

At least one aspect of the invention is directed to a pump system for pumping blood though a body passageway. The pump system includes a distal section having at least one inlet to receive blood, a pumping section in fluid communication with the distal section to receive blood from the distal section, and a pump constructed and arranged to be positioned within the pumping section to draw blood into the pumping section in a first phase of operation and to pump blood out of the at least one outlet valve in a second phase of operation. The pump system may be configured such that the at least one inlet is in fluid communication with the pumping section in both the first phase of operation and the second phase of operation. At least one other aspect of the invention is directed to a pump system for pumping blood from one of the right atrium and the right ventricle to the pulmonary artery.

Claims

1. A pump system for pumping blood through a body passageway, the pump system comprising:

a distal section having at least one inlet to receive blood;

a pumping section in fluid communication with the distal section to receive blood from the distal section, the pumping section sized to fit within a body passageway and having at least one outlet valve; and

a balloon pump constructed and arranged to be positioned within the pumping section to draw blood into the pumping section in a first phase of operation and to pump blood out of the at least one outlet valve in a second phase of operation;

wherein the pump system is configured such that the at least one inlet is in fluid communication with the pumping section in both the first phase of operation and the second phase of operation.

2. The pump system of claim 1, wherein the pumping section and the distal section are configured such that in the second phase of operation, a blood flow rate out of the at least one outlet valve is greater than a blood flow rate out of the at least one inlet.

3. The pump system of claim 2, wherein the pump includes a balloon that is deflated in the first phase of operation and inflated in the second phase of operation.

4. The pump system of claim 3, wherein the balloon is coupled to a lumen to supply a medium to the balloon to inflate the balloon and to extract the medium to deflate the balloon.

5. The pump system of claim 4, wherein the pump system is constructed and arranged to allow percutaneous insertion of at least the distal section and the pumping section into an artery of a patient.

6. The pump system of claim 5, wherein the pumping section includes an expandable cannula.

7. The pump system of claim 6, wherein the expandable cannula includes a channel that is configured to receive a filling medium to expand the expandable cannula.

8. The pump system of claim 2, further comprising at least one anchoring device coupled to at least one of the distal section and the pumping section, wherein the anchoring device is configurable to support the pumping section in an artery of a patient.

9. The pump system of claim 8, wherein the at least one anchoring device includes a balloon that is expandable to support the pumping section in the artery.

10. The pump system of claim 6, further comprising an extraction device constructed and arranged to receive the expandable cannula for extraction of the expandable cannula from a patient.

11. The pump system of claim 10, wherein the extraction device is constructed and arranged to collapse the expandable cannula as the expandable cannula is drawn into the extraction device for removal from the artery.

12. The pump system of claim 1, wherein the pump system is constructed and arranged to operate in a cyclical manner alternating between the first phase of operation and the second phase of operation with the first phase being longer than the second phase.

13. The pump system of claim 1, wherein the distal section is expandable from an insertion state to an operational state.

14. A method of pumping blood in a patient, the method comprising:

inserting a cannula into an artery of a patient, the cannula having a distal end with an opening and a pumping portion containing a balloon, the pumping portion being positioned within the artery and in fluid communication with the opening in the distal end and the pumping portion having at least one outlet;

drawing blood through the opening and into the pumping portion in a first phase of operation; and

pumping blood out of the at least one outlet and out of the opening in a second phase of operation.

15. The method of claim 14, wherein pumping blood includes pumping blood out of the at least one outlet at a first flow rate and pumping blood out of the opening at a second flow rate, wherein the first flow rate is greater than the second flow rate.

16. The method of claim 14, wherein blood is pumped in a cyclical manner alternating between the first phase of operation and the second phase of operation with a period of operation in the first phase being greater than a period of operation in the second phase.

17. The method of claim 14, wherein inserting the cannula includes positioning the distal end in the left ventricle of the patient'"'"'s heart.

18. The method of claim 17, wherein inserting the cannula includes inserting the cannula into the femoral artery of the patient.

19. The method of claim 18, wherein the pumping portion includes an expandable section, and wherein the method further includes expanding the expandable section from an insertion state to an operational state after inserting the cannula into the femoral artery.

20. The method of claim 19, wherein pumping blood includes inflating the balloon.

21. The method of claim 20, wherein inserting the cannula includes positioning the pumping portion in the ascending aorta of the patient.

22. The method of claim 21, wherein the cannula includes at least one anchoring device, and wherein the method further includes using the at least one anchoring device to support the pumping portion in the ascending aorta.

23. The method of claim 19, further comprising moving the expandable section from the operational state to the insertion state by sliding the expandable section into an extraction device.

24. A pump system for pumping blood through a body passageway, the pump system comprising:

a distal section having at least one inlet to receive blood;

a pumping section in fluid communication with the distal section to receive blood from the distal section, the pumping section sized to fit within a body passageway, containing a balloon, and having at least one outlet valve;

means for drawing blood into the pumping section in a first phase of operation and for pumping blood out of the at least one outlet valve in a second phase of operation, such that the at least one inlet is in fluid communication with the pumping section in both the first phase of operation and the second phase of operation.

25. The pump system of claim 24, wherein the means for drawing blood includes means for drawing blood such that in the second phase of operation, a blood flow rate out of the at least one outlet valve is greater than a blood flow rate out of the at least one inlet.

26. The pump system of claim 25, wherein the pump system is constructed and arranged to allow percutaneous insertion of at least the distal section and the pumping section into an artery of a patient.

27. The pump system of claim 26, further comprising means for expanding an expandable portion of the pumping section after insertion of the pumping section into an artery.

28. The pump system of claim 27, further comprising means for anchoring the pumping section in an artery of a patient.

29. The pump system of claim 27, further comprising means for collapsing the expandable portion of the pumping section and withdrawing the pumping section from the artery.

30. The pump system of claim 24, wherein the distal section is expandable from an insertion state to an operational state.

31. A pump system for pumping blood through a body passageway, the pump system comprising:

a distal section having at least one inlet to receive blood;

a pumping section in fluid communication with the distal section to receive blood from the distal section, the pumping section sized to fit within a body passageway and having at least one outlet valve; and

a balloon pump positioned within the pumping section to draw blood into the pumping section in a first phase of operation and to pump blood out of the at least one outlet valve in a second phase of operation;

wherein the balloon pump is constructed and arranged in the pumping section to block a fluid communication path between the pumping section and the distal section in the second phase of operation to prevent blood from exiting the at least one inlet in the second phase of operation.

32. The pump system of claim 31, wherein the balloon pump includes a balloon coupled to a lumen to supply a medium to the balloon to inflate the balloon in the second phase of operation and to extract the medium from the balloon in the first phase of operation.

33. The pump system of claim 32, wherein the pump system is constructed and arranged to allow percutaneous insertion of at least the distal section and the pumping section into an artery of a patient.

34. The pump system of claim 33, wherein the pumping section includes an expandable cannula.

35. The pump system of claim 34, wherein the expandable cannula includes a channel that is configured to receive a filling medium to expand the expandable cannula.

36. A method of pumping blood in a patient, the method comprising:

inserting a cannula into the artery of a patient, the cannula having a distal end with an opening, a pumping portion, a fluid communication path between the opening and the pumping portion, and a balloon disposed in the pumping portion;

deflating the balloon to draw blood through the opening and into the pumping portion in a first phase of operation; and

inflating the balloon to pump blood out of the pumping portion in a second phase of operation;

wherein inflating the balloon includes blocking the fluid communication path with a portion of the balloon.

37. The method of claim 36, wherein the pumping portion includes at least one outflow valve, and wherein inflating the balloon includes pumping blood out of the at least one outflow valve.

38. The method of claim 37, wherein inserting the cannula includes positioning the distal end in the left ventricle of the patient'"'"'s heart.

39. The method of claim 38, wherein inserting the cannula includes inserting the cannula into the femoral artery of the patient.

40. The method of claim 39, wherein the pumping portion includes an expandable section, and wherein the method further includes expanding the expandable section from an insertion state to an operational state after inserting the cannula into the artery.

41. The method of claim 40, wherein inserting the cannula includes positioning the pumping portion in the ascending aorta of the patient.

42. The method of claim 36, wherein the cannula includes at least one anchoring device, and wherein the method further includes using the at least one anchoring device to support the pumping portion in the ascending aorta.

43. The method of claim 40, further comprising moving the expandable section from the operational state to the insertion state by sliding the expandable section into an extraction device.

44. A pump system for pumping blood from a patient'"'"'s right atrium or right ventricle to a patient'"'"'s pulmonary artery, the pump system comprising:

a distal section having at least one outlet;

a pumping section in fluid communication with the distal section to provide blood to the outlet of the distal section, the pumping section sized to fit within the patient'"'"'s aorta and having at least one inlet valve to receive blood; and

a pump constructed and arranged to be positioned within the pumping section to draw blood into the pumping section in a first phase of operation and to pump blood out of the outlet of the distal section in a second phase of operation.

45. The pump system of claim 44, wherein the pump includes a balloon that is deflated in the first phase of operation and inflated in the second phase of operation.

46. The pump system of claim 45, wherein the balloon is coupled to a lumen to supply a medium to the balloon to inflate the balloon and to extract the medium to deflate the balloon.

47. The pump system of claim 46, wherein the pump system is constructed and arranged to allow percutaneous insertion of at least the distal section and the pumping section.

48. The pump system of claim 47, wherein the pumping section includes an expandable cannula.

49. The pump system of claim 48, wherein the expandable cannula includes a channel that is configured to receive a filling medium to expand the expandable cannula.

50. The pump system of claim 44, wherein the at least one inlet valve is a one-way valve configured to permit flow of blood into the pumping section and prevent flow of blood out of the pumping section.

51. A method of pumping blood from a patient'"'"'s right atrium or right ventricle to a patient'"'"'s pulmonary artery, the method comprising:

inserting a cannula into the patient, the cannula having a distal end with at least one outlet and a pumping portion, the pumping portion containing a balloon, being positioned within the patient'"'"'s aorta and in fluid communication with the opening in the distal end and the pumping portion, and having at least one inlet;

drawing blood from the right atrium or the right ventricle through the at least one inlet and into the pumping portion in a first phase of operation; and

pumping blood out of the at least one outlet into the pulmonary artery in a second phase of operation.

52. The method of claim 51, wherein inserting the cannula includes positioning the distal end in the pulmonary artery and positioning the pumping portion in one of the right atrium and the right ventricle.

53. The method of claim 52, wherein the pumping portion includes an expandable section, and wherein the method further includes expanding the expandable section from an insertion state to an operational state after inserting the cannula into the patient.

54. The method of claim 53, wherein pumping blood includes inflating the balloon.