Multi-cartridge fluid delivery device

• US 7,914,499 B2
• Filed: 03/28/2007
• Issued: 03/29/2011
• Est. Priority Date: 03/30/2006
• Status: Active Grant

• Current Assignee: Mannkind Corporation
• Original Assignee: Valeritas, Inc. (Zealand Pharma A/S)
• Inventors: Gonnelli, Robert, Nardi, Ronald V., Levesque, Steven F.
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): Landry, II; Gerald
• Application Number:
  US12/295,173
• Publication Number:
  US 20090240232A1
• Time in Patent Office: 1,462 Days
• Field of Search: 604/19, 604 65- 67, 604118-121, 604131-147, 6048901-8921, 604/151, 604/186
• US Class Current: 604/186
• CPC Class Codes: A61M 5/1407 Infusion of two or more substances
• CPC Class Codes: A61M 5/14526 the piston being actuated by fluid pressure
• CPC Class Codes: A61M 5/1454 spring-actuated, e.g. by a clockwork
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/32 Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001
• CPC Class Codes: A61M 5/3298 Needles arranged in parallel
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics

Abstract

A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments.

Claims

1. A fluid delivery device for administering a first medicament and a second medicament comprising:

a housing;

a first reservoir within the housing and configured to contain the first medicament;

a second reservoir within the housing and configured to contain the second medicament;

a first basal drive mechanism within the housing and having a first hydraulic fluid reservoir;

a first pump chamber in fluid communication with the first hydraulic fluid reservoir of the first basal drive mechanism via a first flow restrictor, the first pump chamber configured to engage the first reservoir to provide a basal delivery of the first medicament during use;

a second basal drive mechanism within the housing and having a second hydraulic fluid reservoir;

a second pump chamber in fluid communication with the second hydraulic fluid reservoir of the second basal drive mechanism via a second flow restrictor, the second pump chamber configured to engage the second reservoir to provide a basal delivery of the second medicament during use; and

a needle having a first end configured for fluid communication with the first reservoir and a second end configured to extend exteriorly from the housing.

2. The fluid delivery device of claim 1, wherein the first and second basal drive mechanisms each include a coil spring coupled to a drive piston.

3. The fluid delivery device of claim 1, further comprising a first delivery piston coupled to the first pump chamber and positioned within the first fluid reservoir to exert a force on the first medicament within the first fluid reservoir and a second delivery piston coupled to the second pump chamber and positioned within the second fluid reservoir to exert a force on the second medicament within the second fluid reservoir.

4. The fluid delivery device of claim 1, further comprising a bolus drive mechanism coupled to the first pump chamber and configured to provide a bolus delivery of the first medicament.

5. The fluid delivery device of claim 1, wherein the needle includes a third end configured for fluid communication with the second reservoir.

6. The fluid delivery device of claim 1, wherein the needle configured for fluid communication with the first reservoir is a first needle, the fluid delivery device further comprising a second needle configured for fluid communication with the second reservoir.

7. The fluid delivery device of claim 1, wherein the device is an ambulatory infusion pump.

8. The fluid delivery device of claim 4, wherein the bolus drive mechanism is coupled to the second pump chamber and is configured to provide a bolus delivery of the second medicament.

9. The fluid delivery device of claim 4, wherein the bolus drive mechanism is a first bolus drive mechanism and wherein the fluid delivery device further comprises a second bolus drive mechanism coupled to the second pump chamber and configured to provide a bolus delivery of the second medicament.

10. The fluid delivery device of claim 4, wherein the bolus drive mechanism includes a ratchet and a bolus piston coupled to the ratchet.

11. The fluid delivery device of claim 8, wherein the bolus of the first medicament is larger than the bolus of the second medicament.

12. A fluid delivery device for administering a first medicament and a second medicament comprising:

a housing;

a first reservoir within the housing and configured to contain the first medicament;

a second reservoir within the housing and configured to contain the second medicament;

a basal drive mechanism within the housing and having a hydraulic fluid reservoir;

a first pump chamber in fluid communication with the hydraulic fluid reservoir of the basal drive mechanism via a first flow restrictor, the first pump chamber configured to engage the first reservoir to provide basal delivery of the first medicament during use; and

a second pump chamber in fluid communication with the hydraulic fluid reservoir of the basal drive mechanism via a second flow restrictor, the second pump chamber configured to engage the second reservoir to provide basal delivery of the second medicaments during use.

13. The fluid delivery device of claim 12, further comprising a bolus drive mechanism coupled to the first and second pump chambers to provide bolus deliveries of the first and second medicaments.

14. The fluid delivery device of claim 12, further comprising a first bolus drive mechanism coupled to the first pump chamber to provide a bolus delivery of the first medicament and a second bolus drive mechanism coupled to the second pump chamber to provide a bolus delivery of the second medicament.

15. The fluid delivery device of claim 12, further comprising a needle having a first end configured for fluid communication with the first reservoir, a second end configured for fluid communication with the second reservoir and a third end configured to engage a user.

16. The fluid delivery device of claim 12, further comprising a first needle configured for fluid communication with the first reservoir and a user and a second needle configured for fluid communication with the second reservoir and the user.

17. The fluid delivery device of claim 12, wherein the device is an ambulatory infusion pump.

18. The fluid delivery device of claim 13, wherein the bolus drive mechanism includes a ratchet and piston.

19. The fluid delivery device of claim 13, wherein the bolus of the first medicament is larger than the bolus of the second medicament.