Container for storing a product to be injected, and an injection device for use with the container

• US 7,914,500 B2
• Filed: 11/30/2006
• Issued: 03/29/2011
• Est. Priority Date: 06/02/2004
• Status: Active Grant

• Current Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Original Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Inventors: Heiniger, Hanspeter, Gafner-Geiser, Simone, Zihlmann, Rudolf
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): HOLLOWAY, IAN KNOBEL
• Application Number:
  US11/564,982
• Publication Number:
  US 20070123820A1
• Time in Patent Office: 1,580 Days
• Field of Search: 222/103, 604131-135, 6048901-8921, 604/192
• US Class Current: 604/192
• CPC Class Codes: A61J 1/06 Ampoules or carpules syringe ampoules or carpules A61M5/28
• CPC Class Codes: A61M 2205/6063 Optical identification systems
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics

Abstract

A container for storing a product to be injected, e.g., a therapeutic or diagnostic liquid, wherein the container includes a container body and a piston body arranged in the container body in a sliding manner, the piston body moveable between a rear end position that determines a maximum filling of the container and a front end position to dispense the product, and wherein the container has a maximum opening ratio H/L of approximately 1.25 to 1.0, H corresponding to the maximum height of the container body and L corresponding to the maximum distance between the lateral wall or walls of the container body.

Claims

1. A container for a substance to be dispensed, the container comprising

a container body having one of a lateral wall or lateral walls and a piston in the container body, the lateral wall or lateral walls and the piston at least partially defining a chamber within the container body for accommodating a substance, the piston having a position that determines a maximum volume of the chamber and being moveable to another position to dispense the substance,

wherein a ratio of a maximum height of the chamber to a maximum distance between the lateral wall or walls of the container body is approximately 1.25 to 1.0.

2. The container according to claim 1, wherein the container body comprises a base that is polygonal and further defines the chamber.

3. The container according to claim 2, wherein the container body comprises an inner surface carrying a coating to reduce at least one of permeation or adsorption of gases and a frictional force between the container body and the piston.

4. The container according to claim 3, wherein an inner surface of at least one of the container body or the container body and a surface of the piston body is provided with a coating to reduce at least one of permeation or adsorption of gases or a frictional force between the container body and the piston body.

5. An injection device for dosed administration of a substance, comprising:

a container comprising a container body having one of a lateral wall or lateral walls and a piston in the container body, the lateral wall or lateral walls and the piston at least partially defining a chamber within the container body for accommodating a substance, the piston sealingly abutting the lateral wall or the lateral walls and having a position that determines a maximum volume of the chamber and being moveable to another position to dispense the substance, wherein a ratio of a maximum height of the chamber to a maximum distance between the lateral wall or walls of the container body is less than approximately 1.25; and

a displacement mechanism for moving the piston in the container to cause an administration of the substance.

6. A container for storing a product to be injected, for example a therapeutic or diagnostic liquid, said container comprising:

a container body comprising side walls; and

a piston body arranged in the container body in a sliding manner, wherein the side walls and the piston body at least partially define a chamber within the container body for storing the product, wherein to dispense the product, the piston body is displaced between a rear end position which determines a maximum volume of the chamber and a front end position;

wherein

an opening ratio of a maximum height of the chamber to a maximum distance between the side walls is at most approximately 1.25; and

wherein

an inner surface of the side walls is provided with a coating to reduce a frictional force between the container body and the piston body.

7. The container according to claim 6, wherein the opening ratio is at most approximately 1.0.

8. The container according to claim 6, wherein a kinetic friction between the container body and the piston body is approximately 20N, and wherein an underpressure required for displacement of the piston body is at most approximately 0.2 bar.

9. The container according to claim 6, wherein a static friction between the container body and the piston body is approximately 40N, and wherein an underpressure required for displacement of the piston body is at most approximately 0.4 bar.

10. A container for storing a product to be injected, in particular a therapeutic or diagnostic liquid, comprising:

a container body comprising side walls; and

a piston body arranged in the container body in a sliding manner, wherein the side walls and the piston body at least partially define a chamber within the container body for storing the product, wherein to dispense the product, can be the piston body is displaced between a rear end position which determines a maximum volume of the chamber filling and a front end position;

wherein

the container body is designed such that, with a kinetic friction of 20N between the container body and the piston body, an underpressure required for displacement of the piston body is at most approximately 0.2 bar.

11. The container according to claim 10, wherein, with a static friction of 40N between the container body and the piston body, an under pressure required for displacement of the piston body is at most approximately 0.4 bar.

12. The container according to claim 10, wherein an inner surface of at least one of the container body or the container body and a surface of the piston body is provided with a coating to reduce at least one of permeation or adsorption of gases or a frictional force between the container body and the piston body.

13. The container according to claim 10, wherein at least the container body is made of cyclo-olefin-copolymer.

14. The container according to claim 10, further comprising a base area that is rectangular.

15. The container according to claim 14, wherein the container body comprises two side walls and a bevel that shortens the two side walls.

16. The container according to claim 10, further comprising a lid for covering the container body, wherein the lid is connected to the container body via a lock.

17. The container according to claim 16, wherein the lock comprises complementary elements arranged substantially centrally on the container body and the lid.

18. The container according to claim 16, wherein the lid comprises a number of recesses at predetermined positions to code for a concentration of the product.

19. The container according to claim 18, wherein the recesses are in a point-symmetrical arrangement.

20. The container according to claim 10, further comprising a tubular outlet for dispensing the product.

21. The container according to claim 20, wherein the tubular outlet is sealed by a piercing membrane.

22. The container according to claim 21, further comprising locking means on an outer circumference of the tubular outlet for receiving, by a force fit, a closure for closing an outlet opening of the tubular outlet.

23. The container according to claim 22, wherein the container body further comprises a bottom defining a trough-shaped recess which merges into an inlet of the tubular outlet.

24. An injection device for the dosed administration of a product, in particular a therapeutic or diagnostic liquid, comprising;

a container comprising a container body and a piston body arranged in the container body such that the piston body is slidable relative to sidewalls of in the container body, wherein the side walls and the piston body at least partially define a chamber within the container body for storing the product, the piston having a rear end position that determines a maximum volume of the chamber and being moveable between the rear end position and a front end position to dispense a maximum amount of produc, wherein an opening ratio of a maximum height of the chamber to a maximum distance between the side walls of the container body is about 1.25 or less; and

a displacement mechanism for displacing the piston body in the container body to administer a dose of the product.

25. The injection device according to claim 24, wherein the displacement mechanism comprises a micro diaphragm pump.

26. The injection device according to claim 25, wherein the displacement of the piston body is in a single direction.

27. The injection device according to claim 24, wherein the container body is designed such that, with a kinetic friction of 20N between the container body and the piston body, an underpressure required for displacement of the piston body is at most approximately 0.2 bar.

28. The injection device according to claim 24, further comprising an outlet for dispensing the product, wherein the outlet extends in a direction that is different than an advancing direction of the piston body.