Method and apparatus for selective material delivery via an intra-renal catheter
First Claim
1. A local renal delivery system, comprising:
- a source comprising a fluid renal protective agent;
a first renal delivery member with a first port that is adapted to be delivered to a first delivery position within a first renal artery via a first corresponding renal ostium located at a first location along an abdominal aortic wall of an abdominal aorta in a patient;
a second renal delivery member with a second port that is adapted to be delivered to a second delivery position within a second renal artery via a second corresponding renal ostium located at a second location along the abdominal aorta wall that is different than the first location; and
a proximal coupler assembly that is adapted to be located externally of the patient when the first and second ports are positioned at the first and second delivery positions, respectively;
wherein the proximal coupler assembly is coupled to the first and second ports so as to deliver the fluid renal protective agent from outside the patient'"'"'s body via the proximal coupler assembly, through the first and second ports at the first and second delivery positions, respectively, and into the first and second renal arteries, also respectively; and
wherein the first and second renal delivery members are self-adjustable between a first shape and a second shape that is a memory shape configuration, such that the renal delivery members are biased to extend away from each other toward the memory shape configuration when unconstrained.
11 Assignments
0 Petitions
Accused Products
Abstract
Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.
291 Citations
89 Claims
-
1. A local renal delivery system, comprising:
-
a source comprising a fluid renal protective agent; a first renal delivery member with a first port that is adapted to be delivered to a first delivery position within a first renal artery via a first corresponding renal ostium located at a first location along an abdominal aortic wall of an abdominal aorta in a patient; a second renal delivery member with a second port that is adapted to be delivered to a second delivery position within a second renal artery via a second corresponding renal ostium located at a second location along the abdominal aorta wall that is different than the first location; and a proximal coupler assembly that is adapted to be located externally of the patient when the first and second ports are positioned at the first and second delivery positions, respectively; wherein the proximal coupler assembly is coupled to the first and second ports so as to deliver the fluid renal protective agent from outside the patient'"'"'s body via the proximal coupler assembly, through the first and second ports at the first and second delivery positions, respectively, and into the first and second renal arteries, also respectively; and wherein the first and second renal delivery members are self-adjustable between a first shape and a second shape that is a memory shape configuration, such that the renal delivery members are biased to extend away from each other toward the memory shape configuration when unconstrained. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89)
-
Specification