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Scanning analyzer for single molecule detection and methods of use

  • US 7,914,734 B2
  • Filed: 12/18/2008
  • Issued: 03/29/2011
  • Est. Priority Date: 12/19/2007
  • Status: Active Grant
First Claim
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1. A single molecule analyzer comprising:

  • (a) an electromagnetic radiation source for providing electromagnetic radiation to a sample container that comprises a sample;

    (b) a system for directing the electromagnetic radiation from the electromagnetic radiation source to an interrogation space in the sample;

    (c) a translating system for translating the interrogation space through at least a portion of the sample, thereby forming a moveable interrogation space; and

    (d) a detector for detecting electromagnetic radiation emitted from a single molecule in the interrogation space if the molecule is present, wherein the detector is operably connected to the interrogation space.

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