Circuit for extracorporeal blood treatment and flow-inverting device therein

• US 7,922,898 B2
• Filed: 05/05/2008
• Issued: 04/12/2011
• Est. Priority Date: 10/31/2003
• Status: Expired due to Fees

• Current Assignee: Gambro Lundia AB (Baxter International Inc.)
• Original Assignee: Gambro Lundia AB (Baxter International Inc.)
• Inventors: Hansson, Per, Jonsson, Lennart, Holmer, Mattias
• Primary Examiner(s): Cecil; Terry K
• Application Number:
  US12/115,160
• Publication Number:
  US 20080208102A1
• Time in Patent Office: 1,072 Days
• Field of Search: 210/97, 210/136, 210/646, 604/6.1, 604/9, 137/597, 137/625.43
• US Class Current: 210/97
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/3658 Indicating the amount of purified blood recirculating in the fistula or shunt
• CPC Class Codes: A61M 1/367 Circuit parts not covered by the preceding subgroups of group A61M1/3621
• CPC Class Codes: A61M 39/223 Multiway valves
• CPC Class Codes: Y10T 137/87249 Multiple inlet with multiple outlet

Abstract

A circuit for extracorporeal blood treatment in which a flow-inverting device is interposed between a blood treatment unit and a blood pump placed on an artery branch connected with a vascular access of a patient. The flow-inverting device allows the blood flow within the filtering unit to be kept unchanged even following an inverted circulation in the patient-side artery and vein branches controlled by the blood pump.

Claims

1. A flow-inverting device for extracorporeal blood treatment circuits comprising:

a first access being designed to be brought into fluid connection with a patient-side artery branch, a second access being designed to be brought into fluid connection with a patient-side vein branch, a third access being designed to be brought into fluid connection with a unit-side artery branch, a fourth access being designed to be brought into fluid connection with a unit-side vein branch, the first access being in selective fluid communication with either the third access or with the fourth access, and the second access in selective fluid communication with either the fourth access or with the third access;

a one-way passage means interposed between at least two of said first, second, third, or fourth accesses to enable flow in only one direction between said at least two accesses, wherein the one-way passage means includes at least one check valve;

a single pump associated with either the first access or the second access, wherein, in a first work condition of the pump, blood is drawn from a patient'"'"'s cardiovascular system and moved towards the flow-inverting device, and wherein, in a second work condition of the pump, blood is drawn from the flow-inverting device and moved towards the patient'"'"'s cardiovascular system; and

a blood treatment unit in fluid communication with the unit-side artery branch and the unit-side vein branch.

2. A device as claimed in claim 1, further comprising a first connecting line bringing the first access into fluid communication with the third access, a second connecting line bringing the first access into fluid communication with the fourth access, a third connecting line bringing the second access into fluid communication with the fourth access, and a fourth connecting line bringing the second access into fluid communication with the third access.

3. A device as claimed in claim 2, wherein the one-way passage means is placed in at least one of said connecting lines.

4. A device as claimed in claim 2, wherein the one-way passage means is placed in each of said first, second, third, and fourth connecting lines to enable flowing in only one direction in each of said connecting lines.

5. A device as claimed in claim 4, wherein the one-way passage means allows a fluid passage in the first connecting line exclusively from the first access to the third access.

6. A device as claimed in claim 4, wherein the one-way passage means allows a fluid passage in the second connecting line exclusively from the fourth access to the first access.

7. A device as claimed in claim 4, wherein the one-way passage means allows a fluid passage in the third connecting line exclusively from the fourth access to the second access.

8. A device as claimed in claim 4, wherein the one-way passage means allows a fluid passage in the fourth connecting line exclusively from the second access to the third access.

9. A device as claimed in claim 2, wherein the one-way passage means comprises at least one check valve for each of said connecting lines.

10. A device as claimed in claim 1, wherein the blood treatment unit includes a dialysis filter, a plasma filter, a hemofilter, or a hemodiafilter.

11. A flow-inverting device for an extracorporeal blood treatment circuit comprising:

a first access being designed to be brought into fluid connection with a first section of a patient'"'"'s cardiovascular system, a second access being designed to be brought into fluid connection with a second section of the patient'"'"'s cardiovascular system downstream from said first section, a third access being designed to be brought into fluid connection with a blood inlet of a blood treatment unit of said circuit, a fourth access being designed to be brought into fluid connection with a blood outlet of the blood treatment unit of said circuit, the first access being in selective fluid communication with either the third access or with the fourth access and the second access in selective fluid communication with either the fourth access or with the third access;

a flow-rectifier automatically allowing one flow exiting the flow-inverting device through the third access and one flow entering the flow-inverting device through the fourth access irrespective of the direction of the flows at the first access and at the second access, wherein the flow rectifier includes a one-way valve between the first access and the third access, a one-way valve between the first access and the fourth access, a one-way valve between the second access and the fourth access, and a one-way valve between the second access and the third access; and

a pump disposed between either the first access and said first section or between the second access and said second section, wherein, in a first work condition of the pump, blood is drawn from the patient'"'"'s cardiovascular system and moved towards the flow-inverting device, and wherein, in a second work condition of the pump, blood is drawn from the flow-inverting device and moved towards the patient'"'"'s cardiovascular system.

12. A disposable blood treatment circuit comprising:

at least one blood treatment unit; and

at least one device for flow inversion according to claim 11.

13. A disposable blood treatment circuit according to claim 12, wherein the third access is connected with a blood inlet of the blood treatment unit of said circuit, and the fourth access is connected with a blood outlet of the blood treatment unit of said circuit.

14. A disposable blood treatment circuit according to claim 13, comprising:

at least one patient-side artery branch and at least one patient-side vein branch designed to be in fluid communication with a patient'"'"'s vascular access;

the first access being connected with the patient-side artery branch, and the second access being connected with the patient-side vein branch,

said inverting device allowing at least one direct operating condition of fluid connection between the patient-side artery branch and the treatment unit blood inlet and an inverted operating condition of fluid connection between the patient-side vein branch and the treatment unit blood inlet.

15. A circuit as claimed in claim 13, wherein the flow-inverting device comprises a first connecting line bringing the first access into fluid communication with the third access, a second connecting line bringing the first access into fluid communication with the fourth access, a third connecting line bringing the second access into fluid communication with the fourth access, and a fourth connecting line bringing the second access into fluid communication with the third access.

16. A circuit as claimed in claim 15, wherein the one-way valves are placed in a corresponding connecting line to enable flow in only one direction in each of said connecting lines.