Treatment of movement disorders with drug therapy
First Claim
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1. A method of operating an implantable stimulator to control a movement disorder, the method comprising:
- implanting a stimulator having at least one infusion outlet into a patient; and
delivering at least one stimulus to at least one vagus nerve of the patient in accordance with one or more stimulation parameters configured to treat a movement disorder, wherein the at least one stimulus comprises at least one drug delivered through the at least one infusion outlet of the stimulator;
wherein the at least one drug increases activity of the at least one vagus nerve in order to, at least in part, alleviate the movement disorder.
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Abstract
Introducing one or more stimulating drugs to the vagus nerve and/or one or more branches of the vagus nerve to treat movement disorders uses at least one implantable system control unit (SCU) with an implantable pump with at least one infusion outlet. Optional electrical stimulation may additionally be supplied by an implantable signal/pulse generator (IPG) with one or more electrodes. In certain embodiments, a single SCU provides one or more stimulating drugs and the optional electrical stimulation. In some embodiments, one or more sensed conditions are used to adjust stimulation parameters.
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Citations
20 Claims
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1. A method of operating an implantable stimulator to control a movement disorder, the method comprising:
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implanting a stimulator having at least one infusion outlet into a patient; and delivering at least one stimulus to at least one vagus nerve of the patient in accordance with one or more stimulation parameters configured to treat a movement disorder, wherein the at least one stimulus comprises at least one drug delivered through the at least one infusion outlet of the stimulator; wherein the at least one drug increases activity of the at least one vagus nerve in order to, at least in part, alleviate the movement disorder. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method of treating a patient with a movement disorder, comprising:
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providing a stimulator; configuring one or more stimulation parameters to treat a movement disorder; programming said stimulator with said one or more stimulation parameters; and applying said stimulus with said stimulator to at least one vagus nerve within said patient in accordance with said one or more stimulation parameters; wherein said stimulus comprises at least one drug that increases activity of the at least one vagus nerve in order to at least in part alleviate said movement disorder. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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Specification