Method and apparatus for sensing field strength signals to estimate location of a wireless implantable marker

• US 7,926,491 B2
• Filed: 03/04/2003
• Issued: 04/19/2011
• Est. Priority Date: 12/31/2002
• Status: Active Grant

• Current Assignee: Varian Medical Systems Incorporated (Siemens AG)
• Original Assignee: Calypso Medical Technologies, Inc. (Siemens AG)
• Inventors: Wright, J. Nelson, Newell, Laurence J.
• Primary Examiner(s): Marmor, II; Charles A
• Assistant Examiner(s): Hopkins; Christine D
• Application Number:
  US10/382,123
• Publication Number:
  US 20040123871A1
• Time in Patent Office: 2,968 Days
• Field of Search: 128/897, 128/899, 600/117, 600/424, 606/130
• US Class Current: 128/899
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 90/36 Image-producing devices or illumination devices not otherwise provided for
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61B 90/98 using electromagnetic means, e.g. transponders
• CPC Class Codes: G01V 15/00 Tags attached to, or associated with, an object, in order to enable detection of the object record carriers for use with machines having a detectable tag or marker G06K19/00
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

Embodiments of the invention are directed to an apparatus for use in a system that senses an excitable wireless target capable of being implanted in a body or tissue. The apparatus includes multiple electromagnetic field sensors arranged approximately in a common plane, and multiple sense signal output paths coupled to the sensors. Each one of the sensors and corresponding output paths is configured to provide an output signal representing at least a portion of an electromagnetic field provided by the marker, where the output signal is proportional to a component of the field at the sensor, where that component is substantially perpendicular to the plane. Various other configurations regarding this apparatus, as well as the overall system and methods of exciting and receiving signals from wireless markers, are also disclosed.

Claims

1. In a medical system for sensing an excitable leadless marker capable of being implanted in and/or affixed to a body, an apparatus comprising:

a rigid support member;

multiple electromagnetic field sensors arranged in a locally planar array on the support member;

multiple sense signal output paths carried by the support member, wherein each sense signal output path is coupled to a single one of the electromagnetic field sensors such that each sense signal output path provides an output signal that represents a substantially perpendicular field component from a single one of the field sensors; and

multiple preamplifiers, wherein each preamplifier is coupled to one of the sense signal output paths, and wherein each preamplifier is a differential amplifier having a high voltage protection snubbing network.

2. The apparatus of claim 1, wherein the support member comprises a flat support panel of a substantially rigid material, and wherein the field sensors are carried by the support panel in a common plane.

3. The apparatus of claim 1, wherein the support member comprises a support panel curved along at least one axis, and wherein the field sensors are carried by the support panel.

4. The apparatus of claim 1, further comprising a flexible sheet, wherein the electromagnetic field sensors and the sense signal paths are conductive depositions on the flexible sheet.

5. The apparatus of claim 1 wherein at least some of the electromagnetic field sensors are arranged as coils having more than 15 windings.

6. The apparatus of claim 1 wherein at least some of the electromagnetic field sensors are arranged as coils having less than 90 windings.

7. The apparatus of claim 1 wherein at least some of the electromagnetic field sensors are arranged as coils.

8. The apparatus of claim 1 wherein at least some of the electromagnetic field sensors are arranged as square spiral coils.

9. The apparatus of claim 1 wherein at least some of the electromagnetic field sensors are arranged as coils having a pitch of approximately 67 millimeters between center points of coils.

10. The apparatus of claim 1 wherein the electromagnetic field sensors include an arrangement of approximately 30 coils of electrically conductive windings.

11. The apparatus of claim 1 wherein the electromagnetic field sensors include an arrangement of coils of electrically conductive traces having a width of approximately 0.15 millimeters.

12. The apparatus of claim 1 wherein the electromagnetic field sensors include an arrangement of coils of electrically conductive traces having a gap width of approximately 0.13 millimeters between adjacent traces in a coil.

13. The apparatus of claim 1 wherein multiple electromagnetic field sensors are configured to receive electromagnetic field signals within a range of 300 to 500 kilohertz.

14. The apparatus of claim 1 wherein the electromagnetic field sensors include an array of coils, wherein each coil receives magnetic flux from the excitable leadless marker and produces a current signal representing an amount of magnetic flux through an inner portion of the coil.

15. The apparatus of claim 1 wherein four electromagnetic field sensors are arranged in an adjacent 2 by 2 array on the support panel.

16. The apparatus of claim 1 wherein the electromagnetic field sensors are arranged in an array having a maximum dimension not greater than approximately 300% of a distance between the array and the leadless marker.

17. The apparatus of claim 1, further comprising at least one electromagnetic field sensor arranged perpendicular to the electromagnetic field sensors arranged in a locally planar array and configured to receive the electromagnetic field emanating from excitation of the leadless marker in a dimension perpendicular to the electromagnetic field sensors arranged in a locally planar array.

18. In a system for energizing a wireless marker to cause the wireless marker to emit a magnetic field signal, and for determining a position of the wireless marker based on the emitted magnetic field signal, wherein the wireless marker is capable of being implanted in and/or affixed to a body, an apparatus for use in the system to receive the emitted magnetic field signal, comprising:

a support panel having a support sheet, a core, a first outer cover and a second outer cover laminated together;

an array of at least three locally planar magnetic field sensors at least partially carried by the support panel and configured to sense substantially normal components of the magnetic field signal at different locations on the support panel, and wherein the field sensors comprise spiral traces of a conductive material on the support sheet; and

three or more active output ports, wherein the active output ports are individually coupled to corresponding magnetic field sensors such that each active output port receives a signal from a single magnetic field sensor and provides an output signal corresponding to one component of the magnetic field signal at the single field sensor.

19. The apparatus of claim 18 wherein the body is organic tissue, and wherein the magnetic field sensors are arranged as approximately planar coils of conductive traces arranged in a substantially rectilinear configuration.

20. In a system for sensing and localizing an excitable wireless marker in or on a human, a sensing system for wirelessly sensing a field emitted by the marker comprising:

a locally planar support panel comprising a support sheet, a core, a first outer cover and a second outer cover laminated together; and

a sensor array including at least four field sensors carried by the support panel, the field sensors being at least substantially similar and locally planar relative to each other, wherein the field sensors comprise spiral traces of a conductive material on the support sheet, and wherein each field sensor is responsive only to substantially normal field components relative to the sensors.

21. The sensing system of claim 20 wherein the sensor array comprises 32 field sensors that are coplanar with each other.

22. The sensing system of claim 20 wherein the field sensors comprise rectilinear coils that are coplanar with each other.

23. The sensing system of claim 20 wherein the field sensors are coils arranged in a generally rectilinear pattern.

24. The sensing system of claim 20 wherein the field sensors comprise rectilinear coils having rectilinear spiral traces of an electrically conductive material

25. The sensing system of claim 20 wherein the marker has a predetermined sensing distance at which it is to be positioned apart from the sensing system, and the field sensors occupy an area having a maximum dimension that is approximately 100% to 300% of the predetermined sensing distance.

26. The sensing system of claim 20 wherein the marker has a predetermined sensing distance at which it is to be positioned apart from the sensing system, and the field sensors occupy an area having a maximum dimension that is approximately 200% of the predetermined sensing distance.

27. The sensing system of claim 20 wherein the field sensors are arranged in a symmetrical pattern.

28. The sensing system of claim 20 wherein the field emitted by the marker has a minimum allowable sensing distance, and the field elements are arranged in a pattern having a pitch between 50% to 200% of the minimum allowable sensing distance.

29. In an application for localizing an implantable marker configured to emit a wirelessly transmitted field for measurement from a predetermined sensing distance, a sensing system comprising:

a support member including a support sheet, a core, a first outer cover and a second outer cover laminated together to form a rigid panel; and

a plurality of field sensors carried by the support member, the field sensors being at least substantially locally planar relative to one another and responsive to field components normal to individual field sensors, the field sensors including coils having a spiral trace of a conductive material on the support sheet, and the field sensors occupy an area having maximum dimension of approximately 100% to 300% of the predetermined sensing distance.

30. The sensing system of claim 29 wherein the field sensors are coplanar with each other.

31. The sensing system of claim 29 wherein the maximum dimension is approximately 200% of the predetermined sensing distance.

32. The sensing system of claim 29 wherein the field sensors are arranged in a symmetrical pattern.

33. A system for determining a target location in a patient, comprising:

a marker having a resonating magnetic circuit configured to wirelessly transmit a field in response to a wirelessly transmitted excitation signal; and

a sensing system comprising (a) a substantially rigid support member including a support sheet, a core, a first outer cover and a second outer cover laminated together and (b) a sensor array including at least four field sensors carried by the support member, and the field sensors being at least a substantially similar and locally planar relative to each other, and wherein the field sensors comprise spiral traces on the support sheet.

34. The system of claim 33 wherein sensor array comprises 32 field sensors that are coplanar with each other.

35. The system of claim 33 wherein the field sensors are rectilinear and coplanar coils.

36. The system of claim 33 wherein the field sensors are coils arranged in a generally rectilinear pattern without a coil in each corner.

37. The system of claim 33 wherein the field sensors comprise rectilinear coils having rectilinear spiral traces of an electrically conductive material.

38. The system of claim 33 wherein the signal transmitted by the marker is to be measured at a predetermined sensing distance and the field sensors occupy an area having a maximum dimension that is approximately 100% to 300% of the predetermined sensing distance.

39. The system of claim 33 wherein the signal transmitted by the marker is to be measured at a predetermined sensing distance and the field sensors occupy an area having a maximum dimension that is approximately 200% of the predetermined sensing distance.

40. The system of claim 33 wherein the sensors are arranged in a symmetrical pattern.

41. The system of claim 33 wherein the signal emitted by the marker has a minimum allowable sensing distance, and the field sensors are arranged in a pattern having a pitch between 50% to 200% of the minimum allowable sensing distance.

42. In a medical system for sensing an excitable leadless marker capable of being implanted in and/or affixed to a body, an apparatus comprising:

a rigid support member;

multiple electromagnetic field sensors arranged in a locally planar array on the support member;

multiple sense signal output paths carried by the support member, wherein each sense signal output path is coupled to a single one of the electromagnetic field sensors such that each sense signal output path provides an output signal that represents a substantially perpendicular field component from a single one of the field sensors;

at least one electromagnetic field sensor arranged perpendicular to the electromagnetic field sensors arranged in a locally planar array and configured to receive the electromagnetic field emanating from excitation of the leadless marker in a dimension perpendicular to the electromagnetic field sensors arranged in a locally planar array; and

multiple preamplifiers, wherein each preamplifier is coupled to one of the sense signal output paths, and wherein each preamplifier is a differential amplifier having a high voltage protection snubbing network.