System and method of aquiring blood-vessel data

• US 7,927,275 B2
• Filed: 08/25/2003
• Issued: 04/19/2011
• Est. Priority Date: 08/26/2002
• Status: Active Grant

• Current Assignee: Cleveland Clinic Foundation
• Original Assignee: Cleveland Clinic Foundation
• Inventors: Klingenamith, Jon D., Nair, Anuja, Vince, D. Geoffrey, Kuban, Barry D.
• Primary Examiner(s): Chen; Tse
• Assistant Examiner(s): Cheng; Jacqueline
• Application Number:
  US10/647,977
• Publication Number:
  US 20040039286A1
• Time in Patent Office: 2,794 Days
• Field of Search: 600/437, 600/428, 600466-468
• US Class Current: 600/437
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 8/543 involving acquisition triggered by a physiological signal
• CPC Class Codes: G06T 2207/30101 Blood vessel; Artery; Vein; Vascular
• CPC Class Codes: G06T 7/0012 Biomedical image inspection

Abstract

A system and method is provided for substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. Specifically, a data-gathering device is adapted to acquire heartbeat data and blood-vessel data from a heart-monitoring device and a data-gathering probe, respectively. In a preferred embodiment of the present invention, the blood-vessel data is acquired during a cyclical portion of the heartbeat data. By identifying a cyclical (or commonly reoccurring) portion of the heartbeat data and acquiring blood-vessel data during this cyclical portion (or during an interval that substantially corresponds thereto), the blood vessel can be analyzed as if it were standing still—i.e., not expanding and relaxing. In one embodiment of the present invention, the heart-monitoring device includes an EKG device, the data-gathering device includes an intra-vascular ultrasound (IVUS) device and a computing device, and the data-gathering probe includes at least one transducer. In another embodiment of the present invention, the data-gathering system further includes a retraction device adapted to move the data-gathering probe though a blood vessel at a substantially steady speed.

Claims

1. A system for acquiring blood-vessel data, comprising:

a data-gathering probe adapted to acquire blood-vessel data;

a heart-monitoring device adapted to acquire heartbeat data;

a device adapted to move said data-gathering probe continuously through a blood vessel at a substantially constant speed, wherein the data-gathering probe gathers data while being continuously moved at the substantially constant speed; and

a data-gathering device connected to said data-gathering probe and said heart-monitoring device and adapted to;

acquire said heartbeat data;

identify a cyclical portion of said heartbeat data, said cyclical portion being substantially common to multiple sets of heartbeat data;

acquire said blood-vessel data during an interval substantially corresponding to said cyclical portion of said heartbeat data, wherein the data-gathering device is adapted to acquire said blood-vessel data only during the interval while the data-gathering probe is moved continuously through the blood vessel at the substantially constant speed in response to a probe-trigger marking a beginning of the cyclical portion; and

permit analysis of the blood vessel as if the blood vessel was standing still, wherein the analysis of the blood vessel is utilized to classify vascular plaque of the blood vessel.

2. The system of claim 1, further comprising a catheter, said data-gathering probe being attached to a distal end of said catheter.

3. The system of claim 2, wherein said data-gathering probe comprises a plurality of transducers spaced circumferentially around said distal end of said catheter and adapted to receive at least said blood-vessel data.

4. The system of claim 2, wherein said data-gathering probe further comprises at least one transducer adapted to rotate and receive at least said blood-vessel data.

5. The system of claim 4, wherein said data-gathering device is further adapted to start acquiring said blood-vessel data when said at least one transducer is rotationally oriented in a predetermined position.

6. The system of claim 1, wherein said heart-monitoring device comprises an electrocardiograph (EKG) device.

7. The system of claim 1, wherein said data-gathering device comprises a programmable computing device.

8. The system of claim 7, wherein said data-gathering device further comprises an intra-vascular ultrasound (IVUS) device.

9. The system of claim 1, wherein said data-gathering device comprises an intra-vascular ultrasound (IVUS) device.

10. The system of claim 1, wherein the device adapted to move said data-gathering probe through a blood vessel comprises a retraction device.

11. A system for acquiring blood-vessel data, comprising:

a computing device adapted to be connected to a data-gathering probe and a heart-monitoring device;

a device adapted to move said data-gathering probe through a blood vessel continuously at a substantially constant speed, wherein the data-gathering probe gathers data while being moved at the substantially constant speed; and

computer code stored on a non-transitory computer readable medium configured to cause said computing device to;

acquire heartbeat data from said heart-monitoring device;

acquire blood-vessel data while the data-gathering probe is continuously moved through the blood vessel at the substantially constant speed during an interval substantially corresponding to a cyclical portion of said heartbeat data, said cyclical portion being a commonly reoccurring portion of said heartbeat data, wherein the computing device is adapted to acquire said blood-vessel data only during the interval in response to a probe-trigger marking a beginning of the cyclical portion; and

permit analysis of the blood vessel as if the blood vessel was standing.

12. The system of claim 11, wherein said computing device is further adapted to be connected to said data-gathering probe via an intra-vascular ultrasound (IVUS) device.

13. The system of claim 11, wherein said data-gathering probe is disposed on a distal end of a catheter having at least one transducer via an intravascular device.

14. The system of claim 11, wherein said heart monitoring device comprises an electrocardiograph (EKG) device.

15. The system of claim 11, wherein said computer code is further adapted to transmit probe-triggering data during said interval, said probe-triggering data signifying a desire to acquire said blood-vessel data from said data-gathering probe.

16. The system of claim 11, wherein said computer code is further adapted to identify a rotational orientation of said data gathering probe.

17. The system of claim 11, wherein said computer code is further adapted to identify a speed at which said retraction device is moving said data-gathering probe through said blood-vessel.

18. The system of claim 11, wherein the device adapted to move said at least one data-gathering probe through a blood vessel comprises a retraction device.

19. The system of claim 11, wherein said data-gathering probe comprises at least one transducer.

20. A method of acquiring blood-vessel data from a patient, comprising:

inserting a data-gathering probe into a blood vessel of a patient;

connecting said data-gathering probe to a data-gathering device;

attaching at least one heart-monitoring device to said patient;

connecting said at least one heart-monitoring device to said data-gathering device;

moving said data-gathering probe through said blood vessel continuously at a substantially constant speed, wherein said data-gathering probe gathers data while being moved at the substantially constant speed;

acquiring heartbeat data from said at least one heart-monitoring device;

identifying a cyclical portion of said heartbeat data that is substantially common to more than one set of heartbeat data;

acquiring blood-vessel data from said data-gathering probe during an interval that substantially corresponds to said cyclical portion of said heartbeat data, wherein the acquiring blood-vessel data step is performed only while the data-gathering probe is continuously moved through the blood vessel at the substantially constant speed and during the interval in response to a probe-trigger marking a beginning of the cyclical portion; and

analyzing the blood vessel as if the blood vessel was standing still.

21. The method of claim 20, wherein said step of inserting a data-gathering probe into a blood vessel further comprises inserting a catheter into said blood vessel.

22. The method of claim 21, wherein said step of connecting said data-gathering probe to a data-gathering device further comprises connecting said catheter to an intra-vascular ultrasound (IVUS) device.

23. The method of claim 22, wherein said step of attaching at least one heart-monitoring device further comprises attaching an electrocardiograph (EKG) device to said patient.

24. The method of claim 23, wherein said step of connecting said at least one heart-monitoring device to said data-gathering device further comprises connecting said EKG device to a computing device connected to said IVUS device.

25. The method of claim 20, wherein said step of acquiring blood-vessel data further comprises receiving blood-vessel data from said data-gathering probe during said interval.

26. The method of claim 20, wherein said step of acquiring blood-vessel data further comprises continuously receiving blood-vessel data from said data-gathering probe and storing blood-vessel data during said interval.

27. The method of claim 20, further comprising the step of rotating at least a portion of said data-gathering probe during the acquisition of said blood-vessel data.

28. The method of claim 27, wherein said step of acquiring blood-vessel data further comprises transmitting probe-triggering data at the beginning of said interval and receiving blood-vessel data from said data-gathering probe in response thereto.

29. The method of claim 27, wherein said step of acquiring blood-vessel data further comprises acquiring blood-vessel data during said interval and when said at least a portion of said data-gathering probe is rotationally oriented in a predetermined position.

30. A method of acquiring blood-vessel data, comprising:

inserting a data-gathering probe into a blood vessel of a patient;

connecting said data-gathering probe to a data-gathering device;

attaching at least one heart-monitoring device to said patient;

connecting said at least one heart-monitoring device to said data-gathering device;

moving said data-gathering probe through said blood vessel continuously at a substantially constant speed, wherein the data-gathering probe gathers data while being moved at the substantially constant speed;

acquiring heartbeat data from said at least one heart-monitoring device over multiple heart cycles;

identifying a cyclical portion of said heartbeat data; and

substantially synchronizing acquiring multiple sets of blood-vessel data to the cyclical portion of the heartbeat data, wherein the acquiring is performed while the data-gathering probe is continuously moved through the blood vessel at the substantially constant speed only during an interval in response to a probe-trigger marking a beginning of the cyclical portion.

31. The method of claim 30, wherein said step of inserting a data-gathering probe further comprises inserting a catheter having at least one transducer into said blood vessel of said patient.

32. The method of claim 31, further comprising the step of identifying a rotational orientation of said at least one transducer.

33. The method of claim 32, wherein said step of substantially synchronizing the acquisition of multiple sets of blood-vessel data to cyclical portions of said multiple sets of heartbeat data further comprises commencing the acquisition of each set of blood-vessel data when said transducer is rotationally oriented in a particular position.

34. The method of claim 30, wherein said step of connecting said data-gathering probe to a data-gathering device further comprises connecting a catheter having at least one transducer to an intra-vascular ultrasound (IVUS) device.

35. The method of claim 30, wherein said step of connecting said at least one heart-monitoring device to said data-gathering device further comprises connecting at least one electrocardiograph (EKG) to a computing device, said computing device further being connected to an intra-vascular ultrasound (IVUS) device.

36. The method of claim 30, further comprising tracking the movement of said data-gathering probe through said blood vessel.

37. A method for gated acquisition of intra-vascular ultrasound (IVUS) data, comprising the steps of:

monitoring a physiological signal of a patient, where the physiological signal correlates with a cardiac cycle for the patient;

advancing an IVUS catheter to a region of interest within a coronary artery;

moving the catheter continuously at a substantially constant speed;

acquiring data while the catheter is continuously moved at the substantially constant speed, wherein the acquiring is performed only during an interval in response to a probe-trigger marking a particular point in the cardiac cycle; and

analyzing the coronary artery as if the coronary artery was standing still.

38. The method of claim 37, wherein said IVUS catheter further comprises a rotating transducer.

39. The method of claim 37, wherein said IVUS catheter further comprises an array of transducers.

40. The method of claim 37 wherein moving the catheter comprises initiating a pullback of the catheter.

41. The method of claim 37, wherein acquiring data is performed while the catheter is pulled back.