Device for irradiating tumour tissue in a patient with a particle beam

• US 7,928,415 B2
• Filed: 12/08/2006
• Issued: 04/19/2011
• Est. Priority Date: 12/22/2005
• Status: Expired due to Fees

• Current Assignee: Gessellschaft Fur Schwerionenforschung MbH
• Original Assignee: Gessellschaft Fur Schwerionenforschung MbH
• Inventors: Kraft, Gerhard, Rietzel, Eike, Bert, Christoph
• Primary Examiner(s): NGUYEN, KIET TUAN
• Application Number:
  US12/086,940
• Publication Number:
  US 20090095921A1
• Time in Patent Office: 1,593 Days
• Field of Search: 250/492.3, 607/1, 607/2
• US Class Current: 250/492.3
• CPC Class Codes: A61N 2005/1059 using cameras imaging the patient
• CPC Class Codes: A61N 2005/1061 using an x-ray imaging system having a separate imaging source
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/103 Treatment planning systems
• CPC Class Codes: A61N 5/1037 taking into account the movement of the target, e.g. 4D-image based planning
• CPC Class Codes: A61N 5/1043 Scanning the radiation beam, e.g. spot scanning or raster scanning
• CPC Class Codes: A61N 5/1049 for verifying the position of the patient with respect to the radiation beam
• CPC Class Codes: A61N 5/1067 in real time, i.e. during treatment
• CPC Class Codes: G21K 1/10 Scattering devices; Absorbing devices; Ionising radiation filters

Abstract

There is proposed a device for the slice-by-slice irradiation of tumour tissue (3) in a patient using a particle beam, having—an accelerator (7) for generating a particle beam (5) with predetermined energy for each slice, —a raster scanning device (9), acting on the particle beam (5), for the slice-by-slice scanning of the tumour tissue (3), —a modulator (17) for modulating the energy of the particle beam (5), —a detection device (37) for the time-resolved detection of the position of the tumour tissue (3) and having—a first storage device for storing data relating to the tumour tissue (3), which were determined prior to the irradiation operation, and for releasing that data to the raster scanning device (9) and to the modulator (17). The device is characterized by—a module (39), which registers the data on the course of the irradiation and the data of the detection device (37) which have been obtained during an irradiation operation.

Claims

1. A method of dose calculation for scanned particle beams for a device for the irradiation with a particle beam of tumour tissue in a patient, the method comprising:

detecting different positions of the tumour tissue during the course of a movement,

dividing the movement into quasi-static movement phases that preferably do not overlap one another,

establishing a partial-irradiation plan of a reference irradiation plan per movement phase, the dose for a movement phase being calculated from the partial-irradiation plan and the associated movement phase,

converting, corresponding to the movement phase, partial doses associated with the movement phases to a reference state and

adding the individual doses to a total dose.

2. A method of claim 1 wherein, during an irradiation, a Bragg maximum from the reference state is converted by means of a correction value into other phases.

3. A method of claim 1 wherein, as correction value there is/are used a vector or a correction triplet to compensate for the movement and/or a pre-irradiation variable taking into account the pre-irradiation.