Infusion pump comprising a computer for calculating the respective maximum permissible dosage

• US 7,931,642 B2
• Filed: 06/07/2004
• Issued: 04/26/2011
• Est. Priority Date: 09/18/1998
• Status: Expired due to Fees

• Current Assignee: Codman Neuro Sciences Sarl
• Original Assignee: Codman Neuro Sciences Sarl
• Inventors: Tonnies, Jan G.
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): Schell; Laura C
• Application Number:
  US10/862,543
• Publication Number:
  US 20050021006A1
• Time in Patent Office: 2,514 Days
• Field of Search: 604 65- 67, 604151-153, 604/246, 604/247, 604/503, 604/504, 604/506, 604/890.1, 604/891.1, 604/30
• US Class Current: 604/890.1
• CPC Class Codes: A61M 2005/1405 Patient controlled analgesia [PCA]
• CPC Class Codes: A61M 2205/3507 with implanted devices, e.g. external control
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence

Abstract

Infusion pump for the delivery of a quantity of a medicament to the body of a patient determinable by means of an electronic control device, the pump being provided with a computer for calculating the maximum permitted administration quantity for each case as a function of the previously delivered quantity and with a blocking device for preventing further administration of the medicament on exceeding a predetermined, permitted maximum value, in which the computer determines the quantity or concentration of the active substance in the body of the patient resulting from the delivered medicament quantity and its breaking down in the body and compares it with the predetermined maximum value.

Claims

1. An infusion pump for the delivery of an amount of a medicament to the body of a patient determinable by means of an electronic control device, the infusion pump comprising:

a) a first computer, the first computer calculating a maximum permitted quantity of the medicament to be administrated each time as a function of a previously delivered quantity and an expected breaking down rate of the medicament,

b) a blocking device, the blocking device preventing further administration of the medicament upon exceeding a predetermined, permitted maximum value, the predetermined, permitted maximum value being a time integral over the infused quantity, reduced by a breaking down resulting from a half-life of the medicament divided by a total quantity of the medicament delivered,

c) the first computer having a memory in which is stored a quantitative figure resulting from a summation of a total delivered medicament amount and a subtracting of a percentage of a quantity entered in the memory resulting from an expected breaking down of the medicament in the body,

d) the first computer having a comparator which constantly compares the quantity entered in the memory with the predetermined, permitted maximum value, and

e) the first computer having a device which, with a predetermined time interval corresponding to the expected breaking down of the medicament in the body, subtracts a fixed percentage of the quantity entered in the memory.

2. An infusion pump according to claim 1, wherein the infusion pump is implantable within the body of the patient and can be operated by an external control device.

3. An infusion pump according to claim 2, wherein the first computer operates the infusion pump and a second computer operates the external control device.

4. An infusion pump for the delivery of an amount of a medicament to the body of a patient determinable by means of an electronic control device, the infusion pump comprising:

a) a first computer, the first computer calculating a maximum permitted quantity of the medicament to be administrated each time as a function of a previously delivered quantity and an expected breaking down rate of the medicament,

b) a blocking device, the blocking device preventing further administration of the medicament upon exceeding a predetermined, permitted maximum value, the predetermined, permitted maximum value being a time integral over the infused quantity reduced by an amount resulting from a half-life of the medicament divided by a total quantity of the medicament delivered,

c) the first computer having a memory in which is stored a quantitative figure resulting from a summation of a total delivered medicament amount and a subtracting of a percentage of a quantity entered in the memory resulting from an expected breaking down of the medicament in the body,

d) the first computer having a comparator which constantly compares the quantity entered in the memory with the predetermined, permitted maximum value, and

e) the first computer having a device which with fixed, predetermined time intervals brings about a subtraction of a percentage of the quantity entered in the memory corresponding to the expected breaking down of the medicament.

5. An infusion pump according to claim 4, wherein the infusion pump is implantable within the body of the patient and can be controlled by an external control device.

6. An infusion pump according to claim 5, wherein the first computer operates the infusion pump and a second computer operates the external control device.