System and method for treating ischemic stroke

• US 7,931,659 B2
• Filed: 08/24/2005
• Issued: 04/26/2011
• Est. Priority Date: 09/10/2004
• Status: Active Grant

• Current Assignee: Penumbra, Inc.
• Original Assignee: Penumbra, Inc.
• Inventors: Gupta, Vikas, Hui, Delilah, Bose, Arani, Donahue, Sean
• Primary Examiner(s): Manahan; Todd E
• Assistant Examiner(s): BACHMAN, LINDSEY MICHELE
• Application Number:
  US11/210,636
• Publication Number:
  US 20060058838A1
• Time in Patent Office: 2,071 Days
• Field of Search: 606/200, 606/127, 606113-114, 606/128, 606/110, 606/111, 606/194, 606/198, 623/1.1, 623/1.23, 604/107
• US Class Current: 606/127
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/22044 with a pointed tip
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector

Abstract

A thromboembolic removal system for treating ischemic stroke includes an elongate member and a receiver on a distal portion of the elongate member. The receiver includes structural members arranged to form a sleeve having a central lumen. A plurality of the structural members form engaging elements having apex regions that extend into the central lumen. During use of the thromboembolic removal system, the receiver is advanced over a body of thromboembolic material within a blood vessel, causing the body to be received into the central lumen, and causing the engaging elements to engage the body within the lumen.

Claims

1. An apparatus for withdrawing thromboembolic material from a blood vessel, the apparatus comprising:

an elongate member; and

a receiver on a distal portion of the elongate member, the receiver formed of a plurality of structural members arranged to form a sleeve having a central lumen, a first plurality of the structural members comprising longitudinally extending struts, a second plurality of the structural members comprising v-shaped engaging elements, and a third set of structural members comprising a plurality of axially spaced-apart circumferential rings attached to the longitudinal struts, each of said v-shaped engaging elements being disposed between adjacent ones of the longitudinal struts and including a first leg extending into the central lumen from a first longitudinal strut and a second leg extending into the central lumen from a second, adjacent longitudinal strut, said first and second legs attached to one another within the central lumen to define a plurality of longitudinally oriented apexes extending into the central lumen, wherein at least a distal row and a proximal row of the v-shaped engaging elements are disposed between a distal circumferential ring and a proximal circumferential ring and each apex is unattached to any other structure within the central lumen.

2. The apparatus of claim 1, wherein the receiver is radially expandable from a compressed position in which the receiver is sized for passage into a blood vessel, to an expanded position in which the receiver is sized to contact an inner surface of the blood vessel when at body temperature.

3. The apparatus of claim 2, wherein, in the expanded position, the receiver is slidable over a body of thromboembolic material within the blood vessel to receive the body into the central lumen, and wherein the engaging elements are oriented to engage the body within the lumen.

4. The apparatus of claim 2, wherein, in the expanded position, the receiver has a maximum expanded diameter in the range of approximately 2-6 mm.

5. The apparatus of claim 2, wherein, in the expanded position, the receiver has a maximum expanded diameter in the range of approximately 6-9 mm.

6. The apparatus of claim 2, further including a catheter having a catheter lumen, the receiver insertable into the catheter lumen when in the compressed position, the receiver configured such that advancement of the receiver out of the catheter causes the receiver to self-expand to its expanded position.

7. The apparatus of claim 6, wherein the receiver is configured such that withdrawal of the receiver into the catheter causes the receiver to collapse to the compressed position.

8. The apparatus of claim 1, wherein the distal circumferential ring is positioned at a distal end of the receiver.

9. The apparatus of claim 1, wherein the proximal circumferential ring is positioned at a proximal end of the receiver.

10. The apparatus of claim 1, wherein a plurality of the longitudinal struts extend between the circumferential rings.

11. The apparatus of claim 1, wherein each longitudinal strut includes at least one spring region.

12. The apparatus of claim 1, wherein the plurality of circumferential rings includes an intermediate ring, and wherein the distal row of v-shaped elements is positioned between the distal ring and the intermediate ring, and the proximal row of v-shaped elements is positioned between the intermediate ring and the proximal ring.

13. The apparatus of claim 1, further including:

an elongate sheath having a sheath lumen proportioned to receive the elongate member; and

an occlusion balloon on the sheath, the balloon inflatable to occlude flow of blood within a blood vessel.

14. The apparatus of claim 1, wherein the receiver is expandable from a first position to a second, radially expanded position, and wherein the engaging elements are foldable during movement of the receiver from the second position to the first position.

15. The apparatus of claim 1, further comprising a plurality of v-shaped elements which include apex regions peripheral to the central lumen.

16. An apparatus for withdrawing thromboembolic material from a blood vessel, the apparatus comprising:

an elongate member; and

a receiver on a distal portion of the elongate member, the receiver formed of a plurality of structural members arranged to form a sleeve having a central lumen, the structural members including longitudinal strut members, v-shaped engaging elements and a plurality of axially spaced-apart circumferential rings attached to the longitudinal struts, each v-shaped engaging element being disposed between adjacent ones of the longitudinal struts and including a first leg extending from a first longitudinal strut member and a second leg extending from a second longitudinal strut member from a fixed position thereon, said second longitudinal strut member adjacent to the first longitudinal strut member, the first leg forming an apex with the second leg, the apex extending into the central lumen, wherein at least a distal row and a proximal row of the v-shaped engaging elements are disposed between a distal circumferential ring and a proximal circumferential ring and wherein the first and second legs extend from a position that is longitudinally fixed relative to the first and second strut members and each apex is unattached to any other structure within the central lumen.

17. The apparatus according to claim 16, wherein the longitudinal strut members have distal ends and the distal circumferential ring extends between the distal ends of the longitudinal strut members, the distal circumferential ring formed of a plurality of strut members extending generally perpendicular to the longitudinal strut members.

18. The apparatus of claim 17, wherein the receiver has a distal end, wherein the longitudinal strut members extend to the distal end of the receiver, and the distal circumferential ring is on the distal end of the receiver.

19. The apparatus of claim 18, wherein the receiver has a proximal end, and wherein the longitudinal strut members extend between the distal and proximal ends of the receiver.

20. The apparatus of claim 17, wherein the elongate member is a tubular member, wherein the longitudinal strut members include proximal ends coupled to the tubular member.

21. The apparatus of claim 17 wherein:

the receiver is radially expandable from a compressed position to an expanded position and the plurality of circumferential rings include a plurality of bend regions, the circumferential rings bendable at the bend regions during movement of the receiver from the expanded position to the compressed position.

22. The apparatus of claim 16, wherein the receiver is expandable from a first position to a second, radially expanded position, and wherein the engaging elements are foldable during movement of the receiver from the second position to the first position.

23. The apparatus of claim 16, wherein the distal circumferential ring defines an opening to the central lumen.