Compositions and methods for increasing adipose metabolism, lipolysis or lipolytic metabolism via thermogenesis

• US 7,935,367 B2
• Filed: 03/08/2007
• Issued: 05/03/2011
• Est. Priority Date: 03/08/2006
• Status: Active Grant

• Current Assignee: Northern Innovations Holding Corp.
• Original Assignee: HHC Formulations Ltd.
• Inventors: Heuer, Marvin, Clement, Ken, Chaudhuri, Shan
• Primary Examiner(s): Mi; Qiuwen
• Application Number:
  US11/715,992
• Publication Number:
  US 20070212429A1
• Time in Patent Office: 1,517 Days
• Field of Search: None
• US Class Current: 424/725
• CPC Class Codes: A23F 3/18 Extraction of water soluble tea constituents A23F3/166 takes precedence; isolation of tea flavour or tea oil A23F3/42
• CPC Class Codes: A23L 33/105 Plant extracts, their artificial duplicates or their derivatives
• CPC Class Codes: A23L 33/11 Plant sterols or derivatives thereof, e.g. phytosterols
• CPC Class Codes: A23L 33/30 Dietetic or nutritional methods, e.g. for losing weight A23L33/10 takes precedence
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/332 Promoters of weight control and weight loss
• CPC Class Codes: A23V 2250/21 Plant extracts
• CPC Class Codes: A23V 2250/2108 Caffeine, coffee extract
• CPC Class Codes: A23V 2250/2136 Phytosterols, phytostanols
• CPC Class Codes: A23V 2250/214 Tea
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/133 having hydroxy groups, e.g. sphingosine
• CPC Class Codes: A61K 31/353 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• CPC Class Codes: A61K 31/475 having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine vincamine A61K31/4375
• CPC Class Codes: A61K 31/522 having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
• CPC Class Codes: A61K 31/6615 Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
• CPC Class Codes: A61K 31/7048 having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin , digitoxin or digoxin
• CPC Class Codes: A61K 36/67 Piperaceae (Pepper family), e.g. Jamaican pepper or kava
• CPC Class Codes: A61K 36/754 Evodia
• CPC Class Codes: A61K 36/82 Theaceae (Tea family), e.g. camellia
• CPC Class Codes: A61K 36/87 : Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
• CPC Class Codes: A61P 3/04 : Anorexiants; Antiobesity agents
• CPC Class Codes: A61P 3/06 : Antihyperlipidemics
• CPC Class Codes: A61P 39/06 : Free radical scavengers or antioxidants

Abstract

A composition and method for promoting weight loss through the mutual and simultaneously to promotion lipolysis, the expenditure of energy stored in the body as fat, the inhibition of lipolysis as well as affording the body of an individual protection from reactive oxygen species resulting from the β-oxidation of fats. The composition comprises at least a lipolytic substance, a thermogenic substance, a substance to inhibit the reformation of triglycerides in the bodily tissues of an individual and an antioxidant.

Claims

1. A diet supplement for promoting weight loss, comprising:

0.005-0.02 g of Evodia rutaecarpa extract;

0.02-0.1 g xanthinol nicotinate;

0.05-0.2 g deanol; and

0.01-0.04 g troxerutin.

2. The diet supplement of claim 1, which comprises 0.02 g troxerutin.

3. The diet supplement of claim 1 comprising 0.05 g xanthinol nicotinate.

4. The diet supplement of claim 1, which comprises at least one of 0.1-0.7 g green tea extract or 0.1-0.5 g caffeine anhydrous.

5. The diet supplement of claim 4, which comprises 0.02 g troxerutin.

6. The diet supplement of claim 4, comprising 0.05 g xanthinol nicotinate.

7. The diet supplement of claim 1 or 4, further comprising an antioxidant selected from the group consisting of an extract of black pepper, Cissus Quadrangularis, and inositol hexaphosphate.

8. The diet supplement of claim 7, which comprises 0.02 g troxerutin.

9. The diet supplement of claim 7, comprising 0.05 g xanthinol nicotinate.

10. The diet supplement of claim 7, further comprising 0.001-0.008 mg black pepper extract, 0.05-0.3 g Cissus Quadrangularis extract or 0.01-0.04 g inositol hexaphosphate.

11. The diet supplement of claim 10, which comprises 0.02 g troxerutin.

12. The diet supplement of claim 10, comprising 0.05 g xanthinol nicotinate.

13. The diet supplement of claim 1 or 7, further comprising 0.001-0.008 mg black pepper extract, 0.05-0.3 g Cissus Quadrangularis extract or 0.01-0.04 g inositol hexaphosphate.

14. The diet supplement of claim 13, which comprises 0.02 g troxerutin.

15. The diet supplement of claim 13, further comprising 0.05 g xanthinol nicotinate.

16. The diet supplement of claim 14, further comprising 0.05 g xanthinol nicotinate.

17. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 1.

18. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 4.

19. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 7.

20. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to any one of claim 1, 7, 4, 10, 2, 16, or 3-12.

21. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 8.

22. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 9.

23. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 10.

24. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 13.

25. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 11.

26. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 14.

27. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 15.

28. A method to aid in the bodily fat loss of an individual, the method comprising the steps of administering to the individual a composition according to claim 16.