Biological material and methods and solutions for preservation thereof
First Claim
1. A method for preserving a biological material selected from the group consisting of cells, cell aggregates, tissue, organs, natural liposomes and synthetic liposomes, the method comprising:
- (a) adding a preservation solution to said biological material, the preservation solution comprising one or more polyphenols and dextran;
(b) freeze drying the biological material; and
(c) storing the biological material under appropriate storing conditions.
4 Assignments
0 Petitions
Accused Products
Abstract
A preservation solution for preserving a biological material at a low temperature including one or more polyphenols, and a method for preserving a biological material are provided. The method includes adding the preservation solution to a biological material, cooling the biological material and storing it under appropriate storing conditions. The method can be used for hypothermic preservation or for cryopreservation, including freezing and lyophilization, of any biological material, including cells selected from RBC, WBC, MNC, UCB, HSC and bacteria. A method is also provided for freezing RBCs such that upon thawing, the RBCs include less than 2% free hemoglobin.
63 Citations
16 Claims
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1. A method for preserving a biological material selected from the group consisting of cells, cell aggregates, tissue, organs, natural liposomes and synthetic liposomes, the method comprising:
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(a) adding a preservation solution to said biological material, the preservation solution comprising one or more polyphenols and dextran; (b) freeze drying the biological material; and (c) storing the biological material under appropriate storing conditions. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 13)
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10. A method for preserving a biological material selected from the group consisting of cells, cell aggregates, tissue, organs, natural liposomes and synthetic liposomes, comprising:
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(a) adding a preservation solution to the biological material, the preservation solution comprising one or more polyphenols, dextran, and being free from any polyalcohol; (b) freeze drying the biological material; and (c) storing the biological material under appropriate storing conditions. - View Dependent Claims (14, 15, 16)
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Specification