Systems for controlling injection and/or imaging procedures

• US 7,937,134 B2
• Filed: 05/23/2007
• Issued: 05/03/2011
• Est. Priority Date: 09/21/1994
• Status: Expired due to Fees

• Current Assignee: Bayer Medical Care Inc. (Bayer AG)
• Original Assignee: Medrad Incorporated (Bayer AG)
• Inventors: Sciulli, Francis J., Hirschman, Alan, Grumski, Walter, Griffiths, David M., Pagano, Vera, Zelenski, Karen, Almon-Martin, Rosemary, Rhinehart, Edward J., Uber, Arthur E.
• Primary Examiner(s): Casler; Brian
• Assistant Examiner(s): KISH, JAMES M
• Application Number:
  US11/752,463
• Publication Number:
  US 20070282198A1
• Time in Patent Office: 1,441 Days
• Field of Search: 600/407, 600/410, 600419-420, 600/425, 600/427, 600431-433, 604/27, 604/31, 604/67, 604/181
• US Class Current: 600/431
• CPC Class Codes: A61B 6/481 involving the use of contrast agents
• CPC Class Codes: A61B 6/504 for diagnosis of blood vessels, e.g. by angiography
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/481 involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream analysis of echo signal exploiting properties of a contrast enhancer in devices for short-range imaging with acoustic waves G01S7/52039
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/80 voice-operated command
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/14546 Front-loading type injectors
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 30/20 for handling medical images, e.g. DICOM, HL7 or PACS

Abstract

A system for producing a contrast-enhanced medical image of a patient includes a source of a contrast or enhancement medium, a pressurizing unit in fluid connection with the source of contrast or enhancement medium, an energy source operable to apply energy to a region of the patient, an imaging unit providing a visual display of an internal view of the patient based upon a signal resulting from the energy applied to the region of the patient, and a control unit. In an embodiment, the signal is affected by a condition of the contrast or enhancement medium in the patient. To control the procedures, the control unit adjusts the condition of the contrast or enhancement medium in the patient based upon the signal. A communication interface preferably enables information between an injector subsystem and an imaging subsystem.

Claims

1. An injector system for use with an imaging system in producing a contrast-enhanced image of an internal region of a patient, the injector system comprising:

(a) first and second pressurizing units for pressurizing a contrast medium and a diluent, respectively, for injection into the patient during an injection procedure;

(b) an injector control unit including programming therefor, the injector control unit operating according to the programming and injection parameters programmed therein for controlling the pressurizing units so as to enable a desired ratio of the contrast medium to the diluent to be injected into the patient during the injection procedure; and

(c) an injector interface in communication with the injector control unit, the injector interface being connectable to the imaging system through an imager interface thereof so as to enable the injector and imaging systems to exchange digital information therebetween for the purpose of enabling at least one of (i) closed loop control of one of the systems by the other of the systems based upon at least one of (A) selected portions of the digital information from at least one of the imaging system and the injector system and (B) a physiological condition of the patient obtained from a sensor thereof and (ii) adjustment of the desired ratio in accordance with the programming and at least some of the digital information received from the imaging system so as to achieve a desired level of enhancement therewith within the internal region of the patient of which the images are acquired by the imaging system during an imaging procedure.

2. The injector system of claim 1 wherein the closed loop control is of the injector system by the imaging system and is based upon at least one of (i) the selected portions of the digital information from at least one of the imaging system and the injector system and (ii) a physiological condition of the patient obtained from a sensor thereof.

3. The injector system of claim 1 wherein the closed loop control is of the imaging system by the injector system and is based upon at least one of (i) the selected portions of the digital information from at least one of the injector system and the imaging system and (ii) a physiological condition of the patient obtained from a sensor thereof.

4. The injector system of claim 1 wherein the injector control unit according to the programming therefor modifies one or more of the injection parameters based on at least some of the digital information received from the imaging system.

5. The injector system of claim 4 wherein the injection parameters include at least one of concentration, flow rate, timing, volume, pressure, temperature, time since preparation, brand, type, number of phases, sequencing of mediums, therapeutic progress, and patient recirculation related data.

6. The injector system of claim 4 wherein the injector control unit according to the programming therefor modifies one or more of the injection parameters based on one or more physiological parameters of the patient.

7. The injector system of claim 4 further including a storage unit wherein the injection parameters are stored for use for subsequent or other injection procedures.

8. The injector system of claim 1 wherein the injector control unit modifies one or more parameters of the imaging system based on at least some of the digital information transmitted from the imaging system.

9. The injector system of claim 1 wherein the digital information includes control parameters, the control parameters comprising hold injection, start injection, start scan, stop injection, stop scan, reset injector subsystem, and gating control operation based on feedback from a physiological parameter of the patient.

10. The injector system of claim 1 wherein the injector interface is for enabling the exchange of a desired portion of the information with at least one of:

(a) a processor unit of the injector control unit;

(b) an operator interface device associated with the injector system, the operator interface device for use in at least one of entering initial settings, entering programming for at least one of the injector and imaging systems, and functioning as a display for at least one of the injector and imaging systems;

(c) a hospital information system from which additional patient information is receivable;

(d) the sensor from which a physiological condition of the patient is receivable; and

(e) a fluid sensor from which a condition of the contrast medium is receivable.

11. The injector system of claim 1 further including a storage unit wherein one or more desired portions of the digital information are storable.

12. An injector system for use with an imaging system in producing a contrast-enhanced image of an internal region of a patient during an imaging procedure, the injector system comprising:

(a) first and second pressurizing units for pressurizing a contrast medium and a diluent, respectively, for injection into the patient during an injection procedure;

(b) an injector control unit including programming therefor, the injector control unit operating according to the programming and injection parameters programmed therein for controlling the pressurizing units so as to enable a desired ratio of the contrast medium to the diluent to be injected into the patient during the injection procedure; and

(c) an injector interface in communication with the injector control unit, the injector interface being connectable to the imaging system through an imager interface thereof so as to enable the injector and imaging systems to exchange digital information therebetween for the purpose of enabling at least one of (i) closed loop control of at least one of the injection and the imaging procedures during which the contrast medium and the diluent is injected into the patient and (ii) adjustment of the desired ratio in accordance with the programming and at least some of the digital information so exchanged so as to achieve a desired level of enhancement therewith within the internal region of the patient of which the images are acquired during the imaging procedure, wherein the closed loop control is based upon at least one of (A) selected portions of the digital information from at least one of the imaging system and the injector system and (B) a physiological condition of the patient obtained from a sensor thereof.

13. The injector system of claim 12 wherein the injector control unit according to the programming therefor modifies one or more of the injection parameters based on at least some of the digital information received from the imaging system.

14. The injector system of claim 13 wherein the injection parameters include at least one of concentration, flow rate, timing, volume, pressure, temperature, time since preparation, brand, type, number of phases, sequencing of mediums, therapeutic progress, and patient recirculation related data.

15. The injector system of claim 13 wherein the injector control unit according to the programming therefor modifies one or more of the injection parameters based on one or more physiological parameters of the patient.

16. The injector system of claim 13 further including a storage unit wherein the injection parameters are stored for use for subsequent or other injection procedures.

17. The injector system of claim 12 wherein the injector control unit modifies one or more parameters of the imaging system based on at least some of the digital information transmitted from the imaging system.

18. The injector system of claim 12 wherein the digital information includes control parameters, the control parameters comprising hold injection, start injection, start scan, stop injection, stop scan, reset injector subsystem, and gating control operation based on feedback from a physiological parameter of the patient.

19. The injector system of claim 12 wherein the injector interface is for enabling the exchange of a desired portion of the information with at least one of:

(a) a processor unit of the injector control unit;

(b) an operator interface device associated with the injector system, the operator interface device for use in at least one of entering initial settings, entering programming for at least one of the injector and imaging systems, and functioning as a display for at least one of the injector and imaging systems;

(c) a hospital information system from which additional patient information is receivable;

(d) the sensor from which a physiological condition of the patient is receivable; and

(e) a fluid sensor from which a condition of the contrast medium is receivable.

20. The injector system of claim 12 further including a storage unit wherein one or more desired portions of the digital information are storable.

21. An injector system for use with an imaging system in producing a contrast-enhanced image of an internal region of a patient, the injector system comprising:

(a) at least one pressurizing unit for pressurizing at least one of a contrast medium and a diluent for injection into the patient during an injection procedure;

(b) an injector control unit including programming therefor, the injector control unit operating according to the programming and injection parameters programmed therein for controlling the at least one pressurizing unit so as to enable a desired ratio of the contrast medium to the diluent to be injected into the patient during the injection procedure; and

(c) an injector interface in communication with the injector control unit, the injector interface being connectable to the imaging system through an imager interface thereof so as to enable the injector and imaging systems to exchange digital information therebetween for the purpose of enabling closed loop control of one of the systems by the other of the systems based upon selected portions of the digital information from at least one of the imaging system and the injector system so as to permit the desired ratio to be adjusted in accordance with the programming and the selected portion(s) of the digital information received from at least one of the imaging and injector systems to achieve a desired level of enhancement therewith within the internal region of the patient of which the images are acquired by the imaging system during an imaging procedure.

22. The injector system of claim 21 wherein the injector control unit according to the programming therefor modifies one or more of the injection parameters based on at least one of (A) at least some of the digital information received from the imaging system and (B) one or more physiological parameters of the patient.

23. The injector system of claim 22 further including a storage unit wherein the injection parameters are stored for use for subsequent or other injection procedures.

24. The injector system of claim 21 wherein the injector control unit modifies one or more parameters of the imaging system based on at least one of (A) at least some of the digital information received from the imaging system, (B) at least some of the digital information received from the injection system and (C) one or more physiological parameters of the patient.