Apparatus and methods for delivery of braided prostheses

• US 7,938,852 B2
• Filed: 02/29/2008
• Issued: 05/10/2011
• Est. Priority Date: 12/03/2001
• Status: Expired due to Term

• Current Assignee: JW Medical Systems Ltd
• Original Assignee: XTENT, Inc.
• Inventors: French, Ron, Andreas, Bernard, Gifford, Hanson S. III, Deem, Mark E., Will, Allan
• Primary Examiner(s): GHERBI, SUZETTE JAIME J
• Application Number:
  US12/040,598
• Publication Number:
  US 20080147162A1
• Time in Patent Office: 1,166 Days
• Field of Search: 623 111- 158
• US Class Current: 623/1.11
• CPC Class Codes: A61B 1/00151 using everted tubes
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/9517 handle assemblies therefor
• CPC Class Codes: A61F 2/966 with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
• CPC Class Codes: Y10S 623/903 Blood vessel

Abstract

Blood vessels and other body lumens are expanded using an evertible braided prosthesis. The braided prosthesis is delivered to the blood vessel in a radially collapsed configuration. A leading edge of the braided prosthesis is then everted so that it expands as it is advanced through the blood vessel. Optionally, the prosthesis can be provided with a biologically active substance in order to inhibit hyperplasia or have other desired biological effects.

Claims

1. An apparatus for delivering a stent to a body lumen, said apparatus comprising:

an elongate flexible shaft having a proximal end, a distal end and a lumen therebetween;

self-expanding tubular stent having a sidewall defining a plurality of apertures therethrough, wherein the apertures are adapted to allow fluid flow therethrough, the stent carried in the flexible shaft lumen at least partially in a radially collapsed configuration and being separated into a first portion having a desired length for deployment and a second portion that remains in the flexible shaft lumen in the collapsed configuration after the apparatus has been removed from the body lumen, wherein upon deployment the first portion is radially expanded into an expanded configuration everted relative to the collapsed configuration;

a slidable member adjacent the flexible shaft for advancing the stent from the flexible shaft lumen so that said stent radially expands into engagement with an inner wall of the body lumen and applies a radially outward force against the inner wall; and

a separation element adjacent the flexible shaft, the separation element adapted to separate the stent into the first portion which is released from the flexible shaft so as to remain in the body lumen while the second portion remains disposed at least partially in the flexible shaft lumen after the apparatus has been removed from the body lumen.

2. The apparatus of claim 1, wherein the stent comprises a braided stent.

3. The apparatus of claim 1, wherein the stent comprises a patterned thin wall tube.

4. The apparatus of claim 1, wherein the stent comprises a metallic structure.

5. The apparatus of claim 1, wherein the-stent comprises a nickel titanium alloy.

6. The apparatus of claim 1, wherein the stent carries a therapeutic agent adapted to be released therefrom in a controlled manner.

7. The apparatus of claim 6, wherein the therapeutic agent inhibits restenosis.

8. The apparatus of claim 1, further comprising an expandable member disposed on the flexible shaft near the distal end.

9. The apparatus of claim 8, wherein the expandable member comprises a balloon.

10. The apparatus of claim 1, wherein the stent everts as it is advanced from the flexible shaft lumen.

11. The apparatus of claim 1, wherein the separation element comprises a severing element adapted to sever the stent into the first portion and the second portion.

12. A method for delivering a stent to a body lumen, said method comprising:

positioning a delivery catheter carrying self-expanding tubular stent having a sidewall defining a plurality of apertures therethrough adapted to allow fluid flow therethrough, to a target site within the body lumen, the stent being into a first portion having a desired length for deployment and a second portion that remains carried within the delivery catheter after the delivery catheter has been removed from the body lumen;

advancing the stent from the delivery catheter into the body lumen;

radially expanding the first portion of the stent from a contracted state to an expanded state, wherein in the expanded state the expanded first portion of the stent is in engagement with an inner wall of the body lumen so as to apply a radially outward force against the inner wall, and wherein the expanded first portion is everted relative to the second portion;

separating the stent into the first portion and the second portion; and

releasing the first portion into the target site while the second portion of the stent remains carried within the delivery catheter after the delivery catheter has been removed from the body lumen.

13. The method of claim 12, wherein the step of separating comprises severing the stent.

14. The method of claim 13, wherein the severing comprises severing the stent with a severing member coupled to the delivery catheter.

15. The method of claim 12, further comprising releasing a therapeutic agent from the first portion after deployment thereof.

16. The method of claim 15, wherein the therapeutic agent inhibits restenosis.

17. The method of claim 12, wherein the step of positioning the delivery catheter comprises carrying the stent in a radially collapsed configuration.

18. The method of claim 12, further comprising expanding an expandable member within the first portion so as to anchor the desired length into the body lumen.

19. The method of claim 18, wherein expanding the expandable member comprises inflating a balloon coupled to the delivery catheter.

20. The method of claim 12, wherein advancing the stent comprises everting the stent so that an inside surface is exposed radially outwardly and advanced over a desired length of a wall of the body lumen.

21. The method of claim 20, wherein the step of everting comprises pushing the stent from the delivery catheter.

22. The method of claim 12, wherein the body lumen is a blood vessel.

23. The method of claim 12, wherein the stent comprises a braided stent.

24. The method of claim 12, wherein the stent comprises a patterned thin wall tube.